Cell division cycle 7-related protein kinase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-(Pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one	IC50	10.0 [1]
	8-Chloro-2-[(2s)-Pyrrolidin-2-Yl][1]benzofuro[3,2-D]pyrimidin-4(3h)-One	IC50	3.4 [1], 118.0 [2], 140.0 [3]
	N-[5-(1-Benzyltriazol-4-yl)-1H-indazol-3-yl]benzamide	Ki	0.4 [1], 0.5 [2], 0.6 [3]
	4-(4-Hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1H)-one	IC50	1.4 [1], 3.0 [2]
	2-(2-Amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one	IC50	7.0 [1]
	8-Bromanyl-2-[[(3s)-3-Oxidanylpyrrolidin-1-Yl]methyl]-3h-[1]benzofuro[3,2-D]pyrimidin-4-One	IC50	7.7 [1], 1471.0 [2]
	2-[[(3S)-3-Aminopyrrolidin-1-yl]methyl]-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one	IC50	10.0 [1], 625.0 [2]
	8-Bromo-2-(pyrrolidin-1-ylmethyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	3.7 [1], 353.0 [2]
	8-Bromo-2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one	IC50	5.5 [1], 1805.0 [2]
	1-(2-Aminopyrimidin-4-yl)indole-6-carbonitrile	IC50	75.0 [1], 5000.0 [2]
	1-[(8-Bromo-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl)methyl]pyrrolidine-3-carboxylic acid	IC50	13.0 [1], 40000.0 [2]
	8-Bromo-2-[(2S,4R)-4-hydroxypyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	9.1 [1], 440.0 [2]
	2-Azetidin-3-yl-8-bromo[1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	7.7 [1], 2536.0 [2]
	8-Bromo-2-{[(3S)-3-(methyloxy)pyrrolidin-1-yl]methyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	11.0 [1], 362.0 [2]
	8-Bromo-2-piperidin-4-yl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	6.2 [1], 1434.0 [2]
	8-Bromo-2-piperidin-3-yl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	15.0 [1], 2356.0 [2]
	8-Bromo-2-[(2S,4S)-4-fluoropyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	11.0 [1], 566.0 [2]
	2-[(2S,4R)-4-Fluoropyrrolidin-2-yl]-8-(methyloxy)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	3.9 [1], 292.0 [2]
	8-Chloro-2-[(2S,4R)-4-fluoropyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	4.0 [1], 167.0 [2]
	2-(1-Aminoethyl)-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one	IC50	7.9 [1], 874.0 [2]
	8-(Methyloxy)-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	6.1 [1], 1374.0 [2]
	8-Bromo-2-[(2R)-pyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one	IC50	70.0 [1], 4592.0 [2]
	8-Bromo-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	4.8 [1], 75.0 [2]
	8-Bromo-2-[(2S,4R)-4-fluoropyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	3.7 [1], 82.0 [2]
	8-Bromo-2-[(2S)-1-methylpyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one	IC50	7.3 [1], 802.0 [2]
	4-(1H-Indol-1-yl)pyrimidin-2-amine	IC50	4700.0 [1], 50000.0 [2]
	5-(1-Benzyl-5-phenyltriazol-4-yl)-1H-indazol-3-amine	Ki	1.2 [1], 2.1 [2]
	5-[1-Benzyl-5-(4-fluorophenyl)triazol-4-yl]-1H-indazol-3-amine	Ki	0.8 [1], 2.2 [2]
	5-(1-Benzyl-5-methyltriazol-4-yl)-1H-indazol-3-amine	Ki	17.0 [1], 23.0 [2]
	N-[5-(1-Benzyltriazol-4-yl)-1H-indazol-3-yl]-3-fluorobenzamide	Ki	0.5 [1], 1.0 [2]
	1-(6-Aminopyrimidin-4-yl)pyrrolo[2,3-b]pyridine-6-carbonitrile	IC50	9.0 [1], 1370.0 [2]
	1-(2-Aminopyridin-4-yl)indole-6-carbonitrile	IC50	9000.0 [1], 50000.0 [2]
	2-Pyrimidinamine, 4-(1H-pyrrolo[2,3-b]pyridin-1-yl)-	IC50	26700.0 [1], 50000.0 [2]
	2-Pyrimidinamine, 4-(6-chloro-1H-pyrrolo[3,2-c]pyridin-1-yl)-	IC50	360.0 [1], 50000.0 [2]
	4-[3-(2-Chloropyridin-3-yl)pyrrolo[3,2-c]pyridin-1-yl]pyrimidin-2-amine	IC50	7.0 [1], 850.0 [2]
	4-[6-Chloro-3-(2-chloropyridin-3-yl)pyrrolo[3,2-c]pyridin-1-yl]pyrimidin-2-amine	IC50	30.0 [1], 2300.0 [2]
	N-[5-(1-Benzyl-5-phenyltriazol-4-yl)-1H-indazol-3-yl]benzamide	Ki	0.8 [1], 0.9 [2]
	N-[5-(1-Benzyl-5-cyclopropyltriazol-4-yl)-1H-indazol-3-yl]-3-fluorobenzamide	Ki	0.9 [1], 2.4 [2]
	Milciclib	IC50	10000.0 [1]
	Pha-793887	IC50	10000.0 [1]
	CID 59604787	IC50	3500.0 [1]
	5-[2,4-Dihydroxy-6-(4-Nitrophenoxy)phenyl]-N-(1-Methylpiperidin-4-Yl)-1,2-Oxazole-3-Carboxamide	IC50	10.0 [1]
	8-[2-Methoxy-5-(4-methylpiperazin-1-yl)anilino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide	IC50	10000.0 [1]
	5-(2-Aminopyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide	IC50	22.0 [1]
	8-Bromo[1]benzofuro[3,2-d]pyrimidin-4(3H)-one	IC50	2000.0 [1]
	4-(1H-Indazol-5-yl)-6-phenylpyrimidin-2(1H)-one	IC50	10.0 [1]
	2-(2-Chloropyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one	IC50	147.0 [1]
	(7S)-2-(2-Aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one	IC50	2.0 [1]
	1H,4H,5H,6H,7H-Pyrrolo[3,2-c]pyridin-4-one	IC50	5000.0 [1]
	2,2-Dimethyl-7-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-1-[(1R)-1-phenylethyl]-3H-quinazolin-4-one	IC50	1000.0 [1]
	3-[(4-Morpholin-4-ylbenzoyl)amino]-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]-1H-thieno[3,2-c]pyrazole-5-carboxamide	IC50	1970.0 [1]
	2-[[(3R)-3-Aminopyrrolidin-1-yl]methyl]-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one	IC50	207.0 [1]
	5-(1-Benzyl-1h-1,2,3-triazol-4-yl)-1h-indazol-3-amine	Ki	12.0 [1]
	4-[[4-Chloro-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amino]cyclohexan-1-ol	Ki	0.16 [1]
	1-N-[4-Chloro-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]-4-N,4-N-dimethylcyclohexane-1,4-diamine	Ki	0.32 [1]
	N-[5-(1-Benzyltriazol-4-yl)-1H-indazol-3-yl]-3-chlorobenzamide	Ki	0.79 [1]
	3-Amino-6-{4-Chloro-3-[(2,3-Difluorophenyl)sulfamoyl]phenyl}-N-Methylpyrazine-2-Carboxamide	IC50	3600.0 [1]
	6-(Cyclohexylamino)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1H-pyridin-2-one	Ki	0.28 [1]
	3-Amino-6-[4-chloro-3-[(3-fluoro-2-methylphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide	IC50	3600.0 [1]
	4-(6-Chloro-1H-indol-1-yl)pyrimidin-2-amine	IC50	66.0 [1]
	4-(6-Bromoindol-1-yl)pyrimidin-2-amine	IC50	350.0 [1]
	N-[5-(2,2-Dimethylpropanoyl)-6,6-dimethyl-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3,5-difluorobenzamide	IC50	10000.0 [1]
	2-(9H-Purin-6-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	178.0 [1]
	2-(2-Aminopyrimidin-4-yl)-7-methyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	6.0 [1]
	2-(2-Aminopyrimidin-4-yl)-7-phenyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	19.0 [1]
	2-(2-Aminopyrimidin-4-yl)-6,6-dimethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	64.0 [1]
	2-[2-(Benzylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	220.0 [1]
	2-[2-(Phenylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	7.0 [1]
	2-(2-Aminopyrimidin-4-yl)-6-(propan-2-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	12.0 [1]
	2-{2-[(Cyclohexylmethyl)amino]pyrimidin-4-yl}-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	655.0 [1]
	2-(2-Aminopyrimidin-4-yl)-7-(propan-2-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	4.0 [1]
	7-Ethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	2.0 [1]
	8,9,10,11-Tetrahydro-3,8,11-triaza-benzo[a]fluoren-7-one	IC50	2.0 [1]
	N-[4-(4-Oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyrimidin-2-yl]benzamide	IC50	262.0 [1]
	2-(2-Aminopyrimidin-4-yl)-6-methyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	26.0 [1]
	2-[2-(Propylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	259.0 [1]
	2-(2-Aminopyrimidin-4-yl)-6-(2-methylpropyl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	8.0 [1]
	2-{2-[(2-Methylpropyl)amino]pyrimidin-4-yl}-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	636.0 [1]
	2-(2-Aminopyrimidin-4-yl)-7,7-diethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	5.0 [1]
	3-Methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	45.0 [1]
	2-{1H-Pyrrolo[2,3-b]pyridin-4-yl}-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	14.0 [1]
	2-(3-Fluoropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	9.0 [1]
	7,7-Dimethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	3.0 [1]
	7-Methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	10.0 [1]
	7,7-Diethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one	IC50	6.0 [1]
	2-(4-Piperazin-1-ylphenyl)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile	IC50	60.0 [1]
	1-Methyl-2-(4-piperazin-1-ylphenyl)pyrrolo[2,3-b]pyridine-4-carbonitrile	IC50	10000.0 [1]
	2-Phenyl-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	50.0 [1]
	2-(2-Methylmorpholin-4-yl)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	66.0 [1]
	2-(4-Methylpiperidin-1-yl)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	105.0 [1]
	2-(Cyclohexylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	21.0 [1]
	2-(Benzylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	20.0 [1]
	2-(2-Hydroxyethylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	37.0 [1]
	2-(3,3-Dimethylbutylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	24.0 [1]
	2-(Furan-2-ylmethylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	15.0 [1]
	2-(Cyclopropylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	33.0 [1]
	5-[(Z)-Pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-2-(thiophen-2-ylmethylamino)-1H-imidazol-4-ol	IC50	18.0 [1]
	2-(Oxolan-2-ylmethylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	21.0 [1]
	2-(Pentylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	35.0 [1]
	2-(Heptylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol	IC50	247.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Cell division cycle 7-related protein kinase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/cell-division-cycle-7-related-protein-kinase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Cell division cycle 7-related protein kinase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cell-division-cycle-7-related-protein-kinase-inhibitors-ic50-ki.
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