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Cellular tumor antigen p53 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
Nutlin-3AIC501390.0 [1], 7100.0 [2]
Sgc-cbp30IC501500.0 [1], 1540.0 [2]
IscheminIC505000.0 [1]
AlpelisibIC5010000.0 [1]
LeniolisibIC503000.0 [1]
2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acidIC50760.0 [1]
2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-1-pentan-3-ylpiperidin-3-yl]acetic acidIC505500.0 [1]
2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acidIC501900.0 [1]
2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-2-oxopiperidin-3-yl]acetic acidIC5034400.0 [1]
2-[(1S)-1-[(2R,3R,4R,5S)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxyhexyl]-1,3,6,8-tetrahydroxyanthracene-9,10-dioneIC506200.0 [1]
[(2R,3R,4S,5S)-5-[(1R)-1,2-Dihydroxyethyl]-4-hydroxy-2-[(1S)-1-(1,3,6,8-tetrahydroxy-9,10-dioxoanthracen-2-yl)hexoxy]oxolan-3-yl] acetateIC506200.0 [1]
9,11-Bis(4-bromophenyl)-4,17-dimethyl-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaeneIC503000.0 [1]
9,11-Bis(4-bromophenyl)-3-ethoxy-17-methyl-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaeneIC506500.0 [1]
9,11-Bis(4-bromophenyl)-4-fluoro-17-methyl-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaeneIC5044300.0 [1]
9,11-Bis(4-chlorophenyl)-17-methyl-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaeneIC509370.0 [1]
11-(4-Bromophenyl)-9-(4-chlorophenyl)-17-methyl-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaeneIC5015000.0 [1]
9,11-Bis(4-bromophenyl)-5-fluoro-4,17-dimethyl-8-oxa-12,13,15,17-tetrazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,13,15-hexaeneIC5011400.0 [1]
2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-ethoxy-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acidIC5010700.0 [1]
2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acidIC504300.0 [1]
2-[(3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-hydroxybutan-2-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acidIC501500.0 [1]
Tert-butyl (2S)-2-[(2S,3R,5R)-3-(3-chlorophenyl)-2-(4-chlorophenyl)-6-oxo-5-(2H-tetrazol-5-ylmethyl)piperidin-1-yl]butanoateIC503100.0 [1]
Tert-butyl (2S)-2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-3-(2H-tetrazol-5-ylmethyl)piperidin-1-yl]butanoateIC501600.0 [1]
Items per page: 1 - 10 of 22
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References

This online tool may be cited as follows

MLA

"Quest Database™ Cellular tumor antigen p53 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/cellular-tumor-antigen-p53-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Cellular tumor antigen p53 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cellular-tumor-antigen-p53-inhibitors-ic50-ki.
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