 | N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea | IC50 | 4.0 [1] |
| N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea | Ki | 1.58 [1], 1.8 [2], 2.95 [3] |
 | Sincalide | Ki | 0.28 [1], 0.3 [2], 0.64 [3], 0.65 [4] |
 | Devazepide | IC50 | 245.0 [1] |
| Devazepide | Ki | 3.69 [1], 29.51 [2], 51.29 [3], 62.0 [4], 87.1 [5] |
 | (4S)-6-[2-[(2R)-2-[(3,5-Dimethylphenyl)methyl]piperidin-1-yl]-2-oxoethyl]-4-(2H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[3,4-d][1,5]benzodiazepin-5-one | Ki | 69.18 [1], 213.8 [2], 1412.54 [3] |
 | Unii-1fgz6L9SF2 | Ki | 24.55 [1], 70.79 [2], 1000.0 [3] |
 | Boc-trp-met-asp-phe-NH2 | IC50 | 25.0 [1] |
| Boc-trp-met-asp-phe-NH2 | Ki | 42.0 [1] |
 | (3S)-1-Methyl-3-[3-(3-methylphenyl)ureido]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one | IC50 | 130.0 [1], 150.0 [2], 151.0 [3], 280.0 [4] |
 | CID 108187 | IC50 | 0.14 [1] |
| CID 108187 | Ki | 0.35 [1], 0.4 [2], 0.98 [3], 1.86 [4] |
 | 2-[2,4-Dioxo-5-phenyl-3-(phenylcarbamoylamino)-1,5-benzodiazepin-1-yl]-N-phenyl-N-propan-2-ylacetamide | IC50 | 23.99 [1], 25.12 [2] |
| 2-[2,4-Dioxo-5-phenyl-3-(phenylcarbamoylamino)-1,5-benzodiazepin-1-yl]-N-phenyl-N-propan-2-ylacetamide | Ki | 25.12 [1] |
 | 1-(4-Chlorophenyl)-3-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]urea | IC50 | 410.0 [1], 540.0 [2], 1100.0 [3] |
 | 1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea | IC50 | 5.5 [1], 12.0 [2], 19.6 [3] |
 | 1-(4-Chlorophenyl)-3-[2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)-5-phenyl-3H-1,4-benzodiazepin-3-yl]urea | IC50 | 0.28 [1], 0.5 [2], 1.6 [3] |
 | Ethyl 2-[3-[(4-chlorophenyl)carbamoylamino]-2-oxo-5-phenyl-3H-1,4-benzodiazepin-1-yl]acetate | IC50 | 1.0 [1], 3.3 [2] |
 | Pentagastrin | IC50 | 6000.0 [1] |
| Pentagastrin | Ki | 14.5 [1], 22.0 [2], 52.0 [3] |
 | Cholecystokinin (27-33), tert-butyloxycarbonyl-nle(28,31)- | IC50 | 0.2 [1], 0.29 [2] |
| Cholecystokinin (27-33), tert-butyloxycarbonyl-nle(28,31)- | Ki | 0.23 [1] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-6-[(2-methylphenyl)carbamoylamino]hexanoyl]-methylamino]-4-oxobutanoic acid | IC50 | 4500.0 [1], 4700.0 [2], 10000.0 [3] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-6-[(2-methylphenyl)carbamoylamino]hexanoyl]amino]-4-oxobutanoic acid | IC50 | 1400.0 [1], 1500.0 [2] |
 | Ethyl 2-[3-[(4-chlorobenzoyl)amino]-5-(2-fluorophenyl)-2-oxo-3H-1,4-benzodiazepin-1-yl]acetate | IC50 | 690.0 [1], 1900.0 [2] |
 | 1-[1-(1-Adamantylmethyl)-2,4-dioxo-5-phenyl-1,5-benzodiazepin-3-yl]-3-phenylurea | Ki | 0.37 [1], 0.71 [2], 2.29 [3], 83.18 [4] |
 | 1-[(3R)-5-Cyclohexyl-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea | IC50 | 0.28 [1] |
 | Tetragastrin | Ki | 10.4 [1], 19.5 [2] |
 | 1-(1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)-3-(3-methylphenyl)urea | IC50 | 3.1 [1], 5.2 [2], 7.1 [3] |
 | Lorglumide | IC50 | 1000.0 [1], 1900.0 [2], 25000.0 [3] |
 | Netazepide | Ki | 0.08 [1], 0.14 [2] |
 | 2-[2-(5-Bromo-1H-indol-3-YL)ethyl]-3-[3-(1-methylethoxy)phenyl]-4-(3H)-quinazolinone | IC50 | 81.0 [1], 160.0 [2] |
 | Spiroglumide | IC50 | 1223.0 [1], 1400.0 [2] |
 | 3-[[2-[5-Cyclohexyl-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-1,3,4-benzotriazepin-3-yl]acetyl]amino]benzoic acid | Ki | 1.0 [1], 5.13 [2] |
 | 4-Chloro-N-[(3S)-5-(2-fluorophenyl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]benzamide | IC50 | 800.0 [1], 2500.0 [2], 2900.0 [3] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-6-[(3-methylphenyl)carbamoylamino]hexanoyl]amino]-4-oxobutanoic acid | IC50 | 1900.0 [1] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-6-[(4-methylphenyl)carbamoylamino]hexanoyl]amino]-4-oxobutanoic acid | IC50 | 1200.0 [1] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-6-[(2-methoxyphenyl)carbamoylamino]hexanoyl]amino]-4-oxobutanoic acid | IC50 | 3400.0 [1], 3800.0 [2] |
 | 1-[2-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-4-bromobenzoyl]-piperidine | Ki | 25.12 [1] |
 | 1-(4-Chlorophenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea | IC50 | 22.0 [1], 23.0 [2], 81.3 [3] |
 | Ethyl 2-[3-[(4-chlorophenyl)carbamoylamino]-5-(2-fluorophenyl)-2-oxo-3H-1,4-benzodiazepin-1-yl]acetate | IC50 | 1.2 [1], 4.1 [2] |
 | 4-Chloro-N-[(3R)-5-(2-fluorophenyl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]benzamide | IC50 | 5200.0 [1], 7600.0 [2], 11000.0 [3] |
 | 1-Methyl-N-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)indole-2-carboxamide | IC50 | 2000.0 [1], 15000.0 [2] |
 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)benzamide | IC50 | 6700.0 [1], 40000.0 [2] |
 | 1-(4-Chlorophenyl)-3-[1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]urea | IC50 | 0.8 [1], 2.6 [2], 8.0 [3] |
 | 1-[1-[2-(3-Azabicyclo[3.2.2]nonan-3-yl)-2-oxoethyl]-5-(2-fluorophenyl)-9-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]-3-[3-(2H-tetrazol-5-yl)phenyl]urea | IC50 | 0.38 [1], 0.68 [2] |
 | (3S)-3-[[(2S)-2-[[(2R)-3-(1H-Indol-3-yl)-2-[[2-[[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-sulfophenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]propanoyl]amino]hexanoyl]amino]-4-oxo-4-(2-phenylethoxy)butanoic acid | IC50 | 7.0 [1], 210.0 [2], 500.0 [3] |
 | (2R,4R)-1-[(2R)-2-(2-Azatricyclo[3.3.1.13,7]decan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methylpropanoyl]-4-(2,4-difluorophenoxy)pyrrolidine-2-carboxylic acid | Ki | 6.8 [1], 17.6 [2], 324.3 [3] |
 | (2R,4R)-1-[(2R)-2-(2-Azatricyclo[3.3.1.13,7]decan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methylpropanoyl]-4-(2,4-dichlorophenoxy)pyrrolidine-2-carboxylic acid | Ki | 1.9 [1], 30.4 [2], 45.7 [3] |
 | (2R,4R)-1-[(2R)-2-(2-Azatricyclo[3.3.1.13,7]decan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methylpropanoyl]-4-(4-nitrophenoxy)pyrrolidine-2-carboxylic acid | Ki | 0.5 [1], 26.3 [2], 75.5 [3] |
 | 2-[2-[2-[2-[2-[[(4R,4As,7S,7aR,12bS)-4a,10-dihydroxy-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]hydrazinyl]-2-oxoethoxy]-N-[2-[3-[[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoylamino]phenoxy]ethyl]acetamide | Ki | 3.9 [1], 57.0 [2], 356.0 [3] |
 | N-[2-[[2-[2-[[(4R,4As,7S,7aR,12bS)-4a,10-dihydroxy-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]ethyl]-2-[2-[2-[3-[[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoylamino]phenoxy]ethylamino]-2-oxoethoxy]acetamide | Ki | 7.3 [1], 33.0 [2], 71.0 [3] |
 | N-[6-[[2-[2-[[(4R,4As,7S,7aR,12bS)-4a,10-dihydroxy-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]hexyl]-2-[2-[2-[3-[[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoylamino]phenoxy]ethylamino]-2-oxoethoxy]acetamide | Ki | 16.3 [1], 77.0 [2], 260.0 [3] |
 | 2-[2-[[(4R,4As,7S,7aR,12bS)-4a,10-dihydroxy-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]-N-[2-[3-[[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]carbamoylamino]phenoxy]ethyl]acetamide | Ki | 14.2 [1], 210.0 [2], 223.0 [3] |
 | (R)-3-Amino-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one | IC50 | 100000.0 [1] |
 | (R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one | IC50 | 100000.0 [1] |
 | Tert-butyl 2-[3-[(3-methylphenyl)carbamoylamino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetate | IC50 | 18.0 [1], 110.0 [2] |
 | Proglumide | IC50 | 900000.0 [1], 2500000.0 [2] |
 | beta-Carboline-3-carboxylic acid methyl ester | IC50 | 100000.0 [1], 150000.0 [2] |
 | Tifluadom | IC50 | 100000.0 [1] |
| Tifluadom | Ki | 100000.0 [1] |
 | CID 132980 | IC50 | 0.1 [1] |
 | Devazepida | IC50 | 720.0 [1] |
| Devazepida | Ki | 169.0 [1] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoic acid | IC50 | 300.0 [1], 500.0 [2] |
 | Gski181771X | IC50 | 2.7 [1], 5.6 [2] |
 | (3S)-3-Amino-4-[[(2S)-1-[[(2R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]-methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid | IC50 | 0.79 [1] |
| (3S)-3-Amino-4-[[(2S)-1-[[(2R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]-methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid | Ki | 2.1 [1] |
 | 2-(2-(1H-Indole-2-carboxamido)benzamido)-3-phenylpropanoic acid | Ki | 10000.0 [1], 22000.0 [2] |
 | 9H-Pyrido[3,4-b]indol-3-amine | IC50 | 100000.0 [1] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]-methylamino]hexanoyl]amino]-4-oxobutanoic acid | Ki | 0.8 [1] |
 | CID 5311148 | IC50 | 1000.0 [1] |
 | N-[4-Chloro-2-(piperidin-1-ylcarbonyl)phenyl]-2,1,3-benzothiadiazole-4-sulfonamide | Ki | 398.11 [1] |
 | 4-[4-Iodo-2-[(5-quinoxalinylsulfonyl)amino]benzoyl]-morpholine | Ki | 31.62 [1] |
 | N-[(3R)-1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide | IC50 | 1400.0 [1], 3700.0 [2] |
 | 2-[3-Methyl-2,4-dioxo-1-[2-oxo-2-(N-propan-2-ylanilino)ethyl]-5-phenyl-1,5-benzodiazepin-3-yl]-N-phenylacetamide | IC50 | 8317.64 [1] |
 | N,N-Diethyl-2-[3-[(3-methylphenyl)carbamoylamino]-2-oxo-5-pyridin-2-yl-3H-1,4-benzodiazepin-1-yl]acetamide | IC50 | 0.56 [1] |
 | (3S)-4-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]hexanoyl]amino]-4-oxobutanoic acid | IC50 | 65.0 [1] |
 | 1-(1-Methyl-2-oxo-5-pyridin-2-yl-3H-1,4-benzodiazepin-3-yl)-3-(3-methylphenyl)urea | IC50 | 66.0 [1] |
 | 1-(5-Azepan-1-yl-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-m-tolyl-urea | IC50 | 1.25 [1], 1.3 [2] |
 | (3S)-3-[[(2S)-2-[[(2S)-2-Acetamido-3-(1H-indol-3-yl)propanoyl]amino]-6-[(2-methylphenyl)carbamoylamino]hexanoyl]amino]-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-methylamino]-4-oxobutanoic acid | IC50 | 5011.87 [1], 6400.0 [2] |
 | 1-(1-Methyl-2-oxo-5-pyrrolidin-1-yl-3H-1,4-benzodiazepin-3-yl)-3-(3-methylphenyl)urea | IC50 | 137.0 [1] |
 | N-(4-Methoxyphenyl)-2-[3-[(1-methylindazol-3-yl)methyl]-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-propan-2-ylacetamide | IC50 | 2398.83 [1] |
 | 2-[3-[(1-Benzylindazol-3-yl)methyl]-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-(4-methoxyphenyl)-N-propan-2-ylacetamide | IC50 | 100000.0 [1] |
 | 2-[3-(1H-Indol-3-ylmethyl)-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-(4-methoxyphenyl)-N-propan-2-ylacetamide | IC50 | 5248.07 [1] |
 | 2-[2,4-Dioxo-5-phenyl-3-(phenylcarbamoylamino)-1,5-benzodiazepin-1-yl]-N-phenylacetamide | IC50 | 31.7 [1], 450.0 [2] |
 | 2-[3-(2H-Indazol-3-ylmethyl)-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-phenyl-N-propan-2-ylacetamide | IC50 | 177.83 [1] |
 | 2-[2,4-Dioxo-1-[2-oxo-2-(N-propan-2-ylanilino)ethyl]-5-phenyl-1,5-benzodiazepin-3-yl]-N-phenylacetamide | IC50 | 831.76 [1] |
| 2-[2,4-Dioxo-1-[2-oxo-2-(N-propan-2-ylanilino)ethyl]-5-phenyl-1,5-benzodiazepin-3-yl]-N-phenylacetamide | Ki | 794.33 [1] |
 | 2-[3-(2H-Indazol-3-ylmethyl)-3-methyl-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-(4-methoxyphenyl)-N-propan-2-ylacetamide | IC50 | 69183.1 [1] |
 | 2-[3-(1H-Indol-3-ylmethyl)-3-methyl-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-(4-methoxyphenyl)-N-propan-2-ylacetamide | IC50 | 17378.01 [1] |
 | Tyr-Gly-Gly-Trp-NMeNle-Asp-Phe-NH2 | Ki | 1.3 [1], 4.8 [2] |
 | 1-[2-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-4-chlorobenzoyl]-piperidine | Ki | 39.81 [1] |
 | Tyr-D-Ala-Gly-D-Trp-NMeNle-Asp-Phe-NH2 | Ki | 1.3 [1], 1.5 [2] |
 | (4R)-6-(2-Fluorophenyl)-4-(1H-indol-3-ylmethyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine | IC50 | 12000.0 [1] |
 | N-[(3S)-1-Methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-4-(trifluoromethyl)benzamide | IC50 | 4600.0 [1], 6200.0 [2] |
 | (3R)-1-Methyl-3-[[4-(trifluoromethyl)benzoyl]amino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one | IC50 | 3300.0 [1], 4200.0 [2] |
Calculator
