Name: Coagulation factor XI Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Coagulation factor XI Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	Methyl N-[4-[5-chloro-2-[(1S)-1-[[(E)-3-[5-chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]amino]-2-phenylethyl]-1H-imidazol-4-yl]phenyl]carbamate	Ki	2.7 ^[1], 3.7 ^[2], 5.8 ^[3]
	Methyl N-[(14S)-14-[[(E)-3-[5-chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]amino]-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate	Ki	1.0 ^[1], 5.0 ^[2]
	(2S)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyacetyl]amino]-N-[(2S)-5-(diaminomethylideneamino)-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]-3-methylbutanamide	IC50	116.0 ^[1], 120.0 ^[2]
	4-[[(1S)-2-[(E)-3-[3-Chloro-2-fluoro-6-(tetrazol-1-yl)phenyl]prop-2-enoyl]-3,4-dihydro-1H-isoquinoline-1-carbonyl]amino]benzoic acid	Ki	3.7 ^[1], 5.0 ^[2]
	4-[[(3S)-2-[(E)-3-[5-Chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]benzoic acid	Ki	1700.0 ^[1], 1737.0 ^[2]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Coagulation factor XI Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 15 Mar. 2026, https://www.aatbio.com/data-sets/coagulation-factor-xi-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2026, March 15). Quest Database™ Coagulation factor XI Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/coagulation-factor-xi-inhibitors-ic50-ki.
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