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Common CD markers used for the differentiation of leukocytes by flow cytometry.

Cluster of differentiation (CD) molecules are cell surface markers widely used in flow cytometry for the identification and characterization of leukocytes and their subsets. These markers, which behave in a variety of sorts, typically act as receptors, co-receptors, ligands or cell adhesion molecules that mediate various immune responses. Since cells often express multiple CD markers at any given time, utilizing a combination of CD markers is especially useful in determining a subpopulation.

Cell Type
Common Human CD Markers
Common Mouse CD Markers
T CellCD3, CD4, CD8CD3, CD4, CD8
B CellCD19, CD20CD45R/B220, CD19, CD 22 (B cell activation marker)
Dendritic CellCD11c, CD123CD11c, CD123
Natural Killer (NK) CellCD56CD335 (NKp46)
Stem Cell/PrecursorCD34 (hematopoietic stem cell only)CD34 (hematopoietic stem cell only)
Monocyte/MacrophageCD14, CD33CD11b/Mac-1, Ly-71 (F4/80)
GranulocyteCD66bCD66b, Gr-1/Ly6G, Ly6C
PlateletCD41, CD61, CD62CD41, CD61 (Integrin Β3), CD9, CD62P (activated platelets)
ErythrocyteCD235aCD235a, Ter-119
Endothelial CellCD146CD146 MECA-32, CD106, CD31, CD62E (activated endothelial cells)
Epithelial CellCD326CD326 (EPCAM1)



References

This online tool may be cited as follows

MLA

"Quest Database™ Common CD markers used for the differentiation of leukocytes by flow cytometry.." AAT Bioquest, Inc.3 May2024https://www.aatbio.com/data-sets/common-cd-markers-used-for-the-differentiation-of-leukocytes-by-flow-cytometry.

APA

AAT Bioquest, Inc. (2024May 3). Quest Database™ Common CD markers used for the differentiation of leukocytes by flow cytometry.. AAT Bioquest. https://www.aatbio.com/data-sets/common-cd-markers-used-for-the-differentiation-of-leukocytes-by-flow-cytometry.
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