Name: Complement factor D Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Complement factor D Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	1-[2-[(1R,3S,5R)-3-[[(1S)-1-(3-Chloro-2-fluorophenyl)ethyl]carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxoethyl]pyrazolo[3,4-c]pyridine-3-carboxamide	IC50	29.0 ^[1], 30.0 ^[2], 70.0 ^[3], 144.0 ^[4]
	Methyl (S)-2-((2-((3-(trifluoromethoxy)phenyl)carbamoyl)pyrrolidine-1-carboxamido)-methyl)benzoate	IC50	14000.0 ^[1]
	Danicopan	IC50	4.0 ^[1], 15.0 ^[2]
	(1R,3S,5R)-3-N-(6-Bromopyridin-2-yl)-2-N-(1-carbamoylindol-3-yl)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxamide	IC50	5.0 ^[1], 6.0 ^[2], 9.0 ^[3]
	(2S)-N-(6-Bromopyridin-2-yl)-3-[2-(3-carbamoylpyrazolo[3,4-b]pyridin-1-yl)acetyl]-1,3-thiazolidine-2-carboxamide	IC50	19.0 ^[1], 27.31 ^[2], 205.0 ^[3]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Complement factor D Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 19 Dec. 2025, https://www.aatbio.com/data-sets/complement-factor-d-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 19). Quest Database™ Complement factor D Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/complement-factor-d-inhibitors-ic50-ki.
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