Cyclin-dependent kinase 1/cyclin B1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Seliciclib	IC50	2400.0 [1]
	Staurosporine	IC50	1.63 [1]
	Alvocidib	IC50	30.0 [1]
	Olomoucine	IC50	7000.0 [1]
	6-O-Cyclohexylmethyl guanine	IC50	7000.0 [1], 26000.0 [2]
	6-O-Cyclohexylmethyl guanine	Ki	5000.0 [1]
	Abemaciclib	IC50	371.0 [1], 1487.0 [2], 1627.0 [3]
	Abemaciclib	Ki	1627.0 [1]
	Sns-032	IC50	480.0 [1]
	Kenpaullone	IC50	400.0 [1]
	4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide	IC50	190.0 [1], 200.0 [2]
	4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide	Ki	190.0 [1]
	O6-Cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine	IC50	9.0 [1], 250.0 [2]
	Quercetin	IC50	20000.0 [1]
	Palbociclib	IC50	10000.0 [1]
	Palbociclib	Ki	5000.0 [1]
	o6-Benzylguanine	IC50	24000.0 [1]
	Indirubin	IC50	10000.0 [1], 20000.0 [2]
	Dinaciclib	IC50	3.0 [1], 72.0 [2]
	Fascaplysin	IC50	100000.0 [1], 250000.0 [2]
	Purvalanol A	IC50	4.0 [1], 610.0 [2]
	6-Cyclohexylmethyloxy-5-nitroso-pyrimidine-2,4-diamine	IC50	2900.0 [1]
	6-Butoxy-9H-purin-2-amine	IC50	32000.0 [1]
	Butyrolactonei	IC50	600.0 [1]
	O6-Allylguanine	IC50	68000.0 [1]
	9H-Purin-2-amine, 6-(2-propyn-1-yloxy)-	IC50	91000.0 [1]
	Purine, 2-amino-6-propoxy-	IC50	75000.0 [1]
	1H-Purin-2-amine, 6-(1-methylethoxy)-	IC50	75000.0 [1]
	{[(2,6-Difluorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide	IC50	980.0 [1]
	6-Bromo-3-[(3E)-3-(2-piperazin-1-ylethoxyimino)indol-2-yl]-1H-indol-2-ol	IC50	200.0 [1], 300.0 [2]
	6-Pentoxy-7H-purin-2-amine	IC50	37000.0 [1]
	9H-Purin-2-amine, 6-(heptyloxy)-	IC50	62000.0 [1]
	9H-Purin-2-amine, 6-(1-methylpropoxy)-	IC50	27000.0 [1]
	O6-Substituted Guanine Deriv. 11	IC50	21000.0 [1]
	9H-Purin-2-amine, 6-(5-hexen-1-yloxy)-	IC50	41000.0 [1]
	O6-Substituted Guanine Deriv. 14	IC50	76000.0 [1]
	9H-Purin-2-amine, 6-[(2-methyl-2-propen-1-yl)oxy]-	IC50	32000.0 [1]
	O6-Substituted Guanine Deriv. 17	IC50	19000.0 [1]
	O6-Substituted Guanine Deriv. 18	IC50	11000.0 [1]
	O6-Substituted Guanine Deriv. 19	IC50	25000.0 [1]
	6-(Cyclopentylmethoxy)-9H-purin-2-amine	IC50	15000.0 [1]
	9H-Purin-2-amine, 6-(1-cyclopenten-1-ylmethoxy)-	IC50	19000.0 [1]
	9H-Purin-2-amine, 6-(1-cyclohexen-1-ylmethoxy)-	IC50	11000.0 [1]
	9H-Purin-2-amine, 6-(3-cyclohexen-1-ylmethoxy)-	IC50	6000.0 [1]
	O6-Substituted Guanine Deriv. 36	IC50	59000.0 [1]
	O6-Substituted Guanine Deriv. 42	IC50	19000.0 [1]
	O6-Substituted Guanine Deriv. 48	IC50	39000.0 [1]
	6-Bromo-3-[(3E)-3-(2-morpholin-4-ylethoxyimino)indol-2-yl]-1H-indol-2-ol	IC50	1100.0 [1], 1800.0 [2]
	6-Bromo-3-[(3E)-3-[2-[4-(2-methoxyethyl)piperazin-1-yl]ethoxyimino]indol-2-yl]-1H-indol-2-ol	IC50	1000.0 [1], 2800.0 [2]
	6-Hydroxy-3-methoxy-4-phenylbenzo[4,3-b]pyridine	IC50	64300.0 [1]
	6-Hydroxy-3-methoxy-4-phenylbenzo[4,3-b]pyridine	Ki	5300.0 [1]
	O6-Substituted Guanine Deriv. 9	IC50	45000.0 [1]
	9H-Purin-2-amine, 6-(2-methylbutoxy)-	IC50	17000.0 [1]
	O6-Substituted Guanine Deriv. 30	IC50	37000.0 [1]
	3-[2-(5-Fluoro-1-methyl-1H-indol-3-yl)-1,3-thiazol-4-yl]-1-methyl-1H-pyrrolo[2,3-b]pyridine	IC50	860.0 [1], 970.0 [2]
	6-Bromo-3-[(3E)-3-[2-(dimethylamino)ethoxyimino]indol-2-yl]-1H-indol-2-ol	IC50	190.0 [1], 490.0 [2]
	8-(4-Methylcyclohexyl)-N-(5-piperazin-1-ylpyridin-2-yl)-4,6,8,11-tetrazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-5-amine	IC50	2660.0 [1], 5200.0 [2]
	6-Methoxy-4-phenyl-3-phenylmethoxy-[1]benzofuro[2,3-b]pyridine	Ki	1000000.0 [1]
	7-Methyl-4-phenyl-3-phenylmethoxy-[1]benzofuro[2,3-b]pyridin-6-ol	Ki	1300.0 [1]
	12-Phenyl-13-phenylmethoxy-17-oxa-15-azatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,8,11,13,15-octaen-8-ol	Ki	90.0 [1]
	Imatinib	IC50	10000.0 [1]
	Genistein	IC50	370000.0 [1]
	Baicalein	IC50	6530.0 [1]
	Baicalin	IC50	14360.0 [1]
	Crizotinib	IC50	10000.0 [1]
	6-Bromoindirubin-3'-oxime	IC50	320.0 [1]
	Doramapimod	IC50	30000.0 [1]
	Purvalanol B	IC50	6.0 [1]
	CID 11612883	IC50	486.0 [1]
	(5e)-5-(Quinolin-6-Ylmethylidene)-2-[(Thiophen-2-Ylmethyl)amino]-1,3-Thiazol-4(5h)-One	Ki	35.0 [1]
	1-Azakenpaullone	IC50	2000.0 [1]
	Hymenialdisine	IC50	22.0 [1]
	Plinabulin	IC50	10100.0 [1]
	9H-Purine-2,6-diamine, N2-(2-aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-, cis-	IC50	382.0 [1]
	Milciclib	IC50	398.0 [1]
	Paullone	IC50	7000.0 [1]
	4-Methyl-5-(2-((4-morpholinophenyl)amino)-pyrimidin-4-yl)thiazol-2-amine	Ki	10000.0 [1]
	Pha-793887	IC50	60.0 [1]
	BS-181	IC50	14000.0 [1]
	2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine	IC50	340.0 [1]
	CID 46209401	IC50	790.0 [1]
	3-(3-Hydroxy-4-methoxyphenyl)-8h-thieno[2,3-b]pyrrolizin-8-one	IC50	5500.0 [1]
	CID 23643976	IC50	79.0 [1]
	CID 44219749	IC50	50000.0 [1]
	Cdk4 Inhibitor	IC50	2100.0 [1]
	RGB-286638 free base	IC50	2.0 [1]
	4-[(E)-(3,5-Diamino-1h-Pyrazol-4-Yl)diazenyl]phenol	IC50	44000.0 [1]
	2'-Hydroxy-4'-Methoxychalcone	IC50	20000.0 [1]
	(3-((6-(2-Methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methanesulfonamide	IC50	3950.0 [1]
	Nms-P937 (nms1286937)	IC50	10000.0 [1]
	Voruciclib	IC50	25.0 [1]
	(2S,3S)-3-((7-(Benzylamino)-3-isopropylpyrazolo[1,5-a]pyrimidin-5-yl)amino)butane-1,2,4-triol	IC50	33.0 [1]
	Amg-925	IC50	2220.0 [1]
	CID 71561915	Ki	4.0 [1]
	4-[[6-(Ethylamino)-2-[[1-(phenylmethyl)-5-indolyl]amino]-4-pyrimidinyl]amino]-1-cyclohexanol	IC50	100000.0 [1]
	IP3K Inhibitor	IC50	100000.0 [1]
	2-(3-Hydroxy-4-methoxystyryl)-8-hydroxyquinoline-7-carboxylic acid	IC50	10000.0 [1]
	(3Z)-3-[(3E)-3-(2,3-Dihydroxypropoxyimino)indolin-2-ylidene]indolin-2-one	IC50	1650.0 [1]
	2,4-Pyrimidinediamine, 5-nitroso-6-(phenylmethoxy)-	IC50	27000.0 [1]
	8-[2-Methoxy-5-(4-methylpiperazin-1-yl)anilino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide	IC50	160.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Cyclin-dependent kinase 1/cyclin B1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/cyclin-dependent-kinase-1-cyclin-b1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Cyclin-dependent kinase 1/cyclin B1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cyclin-dependent-kinase-1-cyclin-b1-inhibitors-ic50-ki.
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