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Cyclin-dependent kinase 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
O6-Cyclohexylmethoxy-2-(4'-sulphamoylanilino) purineIC5080.0 [1]
SeliciclibIC50500.0 [1]
4-Nitro-2-{[4-(methylsulfanyl)benzylidene]amino}phenolIC5069800.0 [1]
OlomoucineIC507000.0 [1]
StaurosporineIC500.1 [1], 0.36 [2], 1.4 [3], 2.6 [4], 3.8 [5]
AlvocidibIC5040.0 [1], 170.0 [2]
AlvocidibKi190.0 [1]
Purvalanol AIC504.0 [1], 35.0 [2], 70.0 [3]
Sns-032IC5038.0 [1], 46.0 [2], 48.0 [3]
Sns-032Ki38.0 [1]
6-O-Cyclohexylmethyl guanineIC5017000.0 [1]
6-O-Cyclohexylmethyl guanineKi1200.0 [1], 12000.0 [2]
Cdk2 Inhibitor IIIC5060.0 [1]
Oxindole-Based Inhibitor 20IC5030.0 [1], 43.0 [2]
2-(2-Chloro-N-[6-[4-[(2S)-3-(dimethylamino)-2-hydroxypropoxy]anilino]pyrimidin-4-yl]-5-methylanilino)acetonitrileIC50140.0 [1], 640.0 [2], 2600.0 [3], 7300.0 [4]
DinaciclibIC501.0 [1]
(3Z)-3-(1H-Imidazol-5-ylmethylene)-5-methoxy-1H-indol-2(3H)-oneIC5022.0 [1], 35.0 [2], 110.0 [3]
6-Cyclohexylmethyloxy-5-nitroso-pyrimidine-2,4-diamineIC502200.0 [1]
6-Cyclohexylmethyloxy-5-nitroso-pyrimidine-2,4-diamineKi1300.0 [1]
4-(1-Isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(methylsulfonyl)phenyl)pyrimidin-2-amineIC506.0 [1]
MilciclibIC5045.0 [1], 363.0 [2]
4-[(7-Hydroxy-6H-pyrrolo[2,3-g][1,3]benzothiazol-8-yl)methylideneamino]-N-pyridin-2-ylbenzenesulfonamideIC509.7 [1], 10.0 [2]
Oxindole-Based Inhibitor 29IC501.5 [1]
Oxindole-Based Inhibitor 22IC502.3 [1]
4-[1-(2-Hydroxy-1H-indol-3-yl)ethylideneamino]benzenesulfonamideIC50360.0 [1]
4-[[5-(Dimethylamino)-2-hydroxy-1H-indol-3-yl]methylideneamino]benzenesulfonamideIC50310.0 [1]
4-[(7-Hydroxy-6H-pyrrolo[2,3-g][1,3]benzothiazol-8-yl)methylideneamino]benzenesulfonamideIC502.8 [1]
Oxindole-Based Inhibitor 60IC508.9 [1]
Oxindole-Based Inhibitor 66IC5075.0 [1]
Oxindole-Based Inhibitor 43IC5046.0 [1]
TrkA InhibitorIC50690.0 [1]
Oxindole-Based Inhibitor 27IC502.5 [1]
Oxindole-Based Inhibitor 31IC503.4 [1]
Oxindole-Based Inhibitor 49IC5016.0 [1]
Oxindole-Based Inhibitor 50IC5043.0 [1]
Oxindole-Based Inhibitor 56IC504.5 [1]
[4-(2-Amino-4-methyl-thiazol-5-YL)-pyrimidin-2-YL]-(3-nitro-phenyl)-amineKi2.0 [1]
1-(Dimethylamino)-3-[4-[[4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]phenoxy]propan-2-olIC501.0 [1], 10.0 [2], 32.0 [3]
(2S)-1-N-(5-Isoquinolin-6-yl-1,3,4-thiadiazol-2-yl)-3-[4-(trifluoromethyl)phenyl]propane-1,2-diamineIC5050.0 [1], 53.0 [2]
Oxindole-Based Inhibitor 57IC5017.0 [1]
4-[(2-Hydroxy-7-methyl-1H-indol-3-yl)methylideneamino]benzenesulfonamideIC501000.0 [1], 10000.0 [2]
Oxindole-Based Inhibitor 44IC5010.0 [1]
Oxindole-Based Inhibitor 61IC502.1 [1]
4-[[2-Hydroxy-4-(hydroxymethyl)-1H-indol-3-yl]methylideneamino]benzenesulfonamideIC5054.0 [1]
4-[1-(5-Chloro-2-hydroxy-1H-indol-3-yl)ethylideneamino]benzenesulfonamideIC5022.0 [1]
4-[[5-(Methoxycarbonyl)-2-oxoindoline-3-ylidenemethyl]amino]benzenesulfonamideIC502.1 [1]
4-[[2-Hydroxy-6-(hydroxymethyl)-1H-indol-3-yl]methylideneamino]benzenesulfonamideIC5061.0 [1]
Oxindole-Based Inhibitor 40IC501000.0 [1]
Oxindole-Based Inhibitor 17IC50120.0 [1]
Oxindole-Based Inhibitor 25IC504.6 [1]
Oxindole-Based Inhibitor 26IC507.9 [1]
Oxindole-Based Inhibitor 28IC501.2 [1]
Oxindole-Based Inhibitor 30IC5093.0 [1]
Oxindole-Based Inhibitor 32IC5013.0 [1]
Oxindole-Based Inhibitor 35IC5012.0 [1]
Oxindole-Based Inhibitor 36IC5019.0 [1]
Oxindole-Based Inhibitor 39IC502400.0 [1]
Oxindole-Based Inhibitor 41IC5034.0 [1]
Oxindole-Based Inhibitor 42IC5011.0 [1]
Oxindole-Based Inhibitor 45IC5012.0 [1]
Oxindole-Based Inhibitor 46IC5015.0 [1]
4-[(5-Amino-2-hydroxy-1H-indol-3-yl)diazenyl]benzenesulfonamideIC5074.0 [1]
Oxindole-Based Inhibitor 64IC5043.0 [1]
Oxindole-Based Inhibitor 65IC5021.0 [1]
Oxindole-Based Inhibitor 69IC501000.0 [1], 10000.0 [2]
Oxindole-Based Inhibitor 73IC5013.0 [1]
Oxindole-Based Inhibitor 74IC5054.0 [1]
Oxindole-Based Inhibitor 75IC504.6 [1]
4-[(5-Chloro-2-hydroxy-7-methyl-1H-indol-3-yl)methylideneamino]benzenesulfonamideIC501000.0 [1], 10000.0 [2]
4-[(4-Imidazo[1,2-A]pyridin-3-ylpyrimidin-2-YL)amino]benzenesulfonamideIC501.0 [1], 2.0 [2], 3.0 [3]
Benzofuranone deriv. 4IC501280.0 [1]
Benzofuranone deriv. 5IC503970.0 [1]
Benzofuranone deriv. 6IC50310.0 [1]
Benzofuranone deriv. 7IC5030.0 [1]
DasatinibIC505000.0 [1]
TofacitinibIC5010000.0 [1]
PalbociclibIC5010.0 [1], 5000.0 [2]
IndazoleIC50185000.0 [1]
N-(4-Methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-YL)ureaIC50100000.0 [1]
Purvalanol BIC506.0 [1], 9.0 [2]
FascaplysinIC50500000.0 [1]
4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamideIC5047.0 [1]
(16E)-14-Methyl-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8,10,12(26),16,21,23-decaeneIC503.0 [1], 130.0 [2]
PDGF Receptor Tyrosine Kinase Inhibitor IVIC5010000.0 [1]
1-Tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amineIC505.0 [1], 29000.0 [2]
1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amineIC5015.0 [1], 18000.0 [2]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 13IC505.0 [1]
N-[5-Bromo-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamideIC501000.0 [1]
Aristolactam AIIIaIC50140.0 [1]
N-(6-Phenyl-1H-indazol-3-yl)cyclopropanecarboxamideIC501000.0 [1]
Oxindole-Based Inhibitor 81IC501.6 [1]
N-[6-(Furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamideIC501000.0 [1]
N-[6-(3-Sulfamoylphenyl)-1H-indazol-3-yl]cyclopropanecarboxamideIC501000.0 [1]
N-(2-Chloro-6-methylphenyl)-2-[(2,6-dimethylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamideIC5025000.0 [1]
4-[[5-(Isobutoxycarbonyl)-2-oxoindoline-3-ylidenemethyl]amino]benzenesulfonamideIC503.0 [1]
Oxindole-Based Inhibitor 33IC5021.0 [1]
Oxindole-Based Inhibitor 58IC5012.0 [1]
Oxindole-Based Inhibitor 59IC5025.0 [1]
Oxindole-Based Inhibitor 62IC506.8 [1]
N'-(Pyrrolidino[2,1-B]isoindolin-4-ON-8-YL)-N-(pyridin-2-YL)ureaIC5080.0 [1], 440.0 [2]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Cyclin-dependent kinase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/cyclin-dependent-kinase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Cyclin-dependent kinase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cyclin-dependent-kinase-2-inhibitors-ic50-ki.
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