Name: Cyclin-dependent kinase 8/19 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Cyclin-dependent kinase 8/19 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	8-(3-Chloro-5-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one	IC50	5.0 ^[1]
	8-[2-Azanyl-3-Chloranyl-5-(1-Methylindazol-5-Yl)pyridin-4-Yl]-2,8-Diazaspiro[4.5]decan-1-One	IC50	11.8 ^[1]
	8-[3-(3-Azanyl-2~{h}-Indazol-6-Yl)-5-Chloranyl-Pyridin-4-Yl]-2,8-Diazaspiro[4.5]decan-1-One	IC50	13.6 ^[1]
	8-[3-Chloro-5-(1-methyl-2,2-dioxo-3H-2,1-benzothiazol-5-yl)pyridin-4-yl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one	IC50	1.4 ^[1]
	5-[5-Chloro-4-[1-(2-methoxyethyl)-1,8-diazaspiro[4.5]decan-8-yl]pyridin-3-yl]-1-methyl-3H-2,1-benzothiazole 2,2-dioxide	IC50	73.5 ^[1]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Cyclin-dependent kinase 8/19 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 13 Dec. 2025, https://www.aatbio.com/data-sets/cyclin-dependent-kinase-8-19-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 13). Quest Database™ Cyclin-dependent kinase 8/19 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cyclin-dependent-kinase-8-19-inhibitors-ic50-ki.
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