 | Celecoxib | IC50 | 80.0 [1] |
 | Indomethacin | IC50 | 900.0 [1] |
| Indomethacin | Ki | 1500.0 [1] |
 | Rofecoxib | IC50 | 300.0 [1] |
 | Ibuprofen | IC50 | 1400.0 [1] |
 | 5-Bromo-2-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)thiophene | IC50 | 30.0 [1] |
 | N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide | IC50 | 610.0 [1] |
 | Aspirin | IC50 | 19800.0 [1] |
| Aspirin | Ki | 52000.0 [1] |
 | Diclofenac | IC50 | 50.0 [1] |
 | Nimesulide | IC50 | 700.0 [1] |
 | 1-((4-Methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole | IC50 | 100.0 [1] |
 | Etoricoxib | IC50 | 810.0 [1] |
 | Valdecoxib | IC50 | 40.0 [1] |
 | Resveratrol | IC50 | 1300.0 [1] |
 | 1-Fluoro-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene | IC50 | 26.0 [1] |
 | Naproxen | IC50 | 12400.0 [1] |
 | Lumiracoxib | IC50 | 130.0 [1] |
| Lumiracoxib | Ki | 320.0 [1] |
 | Carprofen | IC50 | 100.0 [1], 102.0 [2], 3900.0 [3], 38000.0 [4] |
 | 3-(3,4-Difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone | IC50 | 30.0 [1], 230.0 [2], 480.0 [3], 900.0 [4] |
 | 1-Methoxy-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene | IC50 | 0.5 [1], 5.0 [2], 5.01 [3], 7.0 [4] |
 | Ketoprofen | IC50 | 26.0 [1], 61.0 [2], 690.0 [3], 3800.0 [4] |
 | Flurbiprofen | IC50 | 10.0 [1], 1060.0 [2], 1995.26 [3] |
 | Flufenamic acid | IC50 | 16.0 [1], 20.0 [2], 9300.0 [3] |
 | 4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide | IC50 | 0.45 [1], 10.0 [2] |
 | Thioflosulide | IC50 | 20.0 [1], 23.0 [2], 29.0 [3], 140.0 [4] |
 | 4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide | IC50 | 32.0 [1], 32.36 [2], 160.0 [3] |
 | 3-(5-Chlorofuran-2-yl)-4-phenyl-5-methylisoxazole | IC50 | 100000.0 [1] |
 | 3-[[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]methyl]-1-(4-methylsulfonylphenyl)-5-phenylpyrazole | IC50 | 45.0 [1], 50.0 [2], 9700.0 [3] |
 | N-(3-Phenoxy-4-pyridinyl)trifluoromethanesulfonamide | IC50 | 400.0 [1], 620.0 [2] |
 | 1-Fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-dimethyl-1-cyclopentenyl]benzene | IC50 | 15.0 [1], 15.14 [2], 15000.0 [3] |
 | 4-[6-(4-Fluorophenyl)spiro[2.4]hept-5-en-5-yl]benzenesulfonamide | IC50 | 3.0 [1], 3.02 [2] |
 | 1-(5-Chloro-1,3-benzoxazol-2-yl)-N-[(1S,2S)-2-phenylmethoxycyclopentyl]piperidine-4-carboxamide | IC50 | 34.7 [1], 934.0 [2], 7560.0 [3], 100000.0 [4] |
 | 5-(4-Fluorophenyl)-6-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene | IC50 | 1.1 [1], 7.59 [2], 8.0 [3] |
 | Oleanolic acid | IC50 | 87000.0 [1], 295000.0 [2] |
 | Meloxicam | IC50 | 160.0 [1], 490.0 [2], 700.0 [3] |
 | Wogonin | IC50 | 46000.0 [1] |
 | 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole | IC50 | 6300.0 [1], 10000.0 [2], 74900.0 [3] |
 | (1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one | IC50 | 11060.0 [1], 79200.0 [2], 100000.0 [3] |
 | Licofelone | IC50 | 370.0 [1], 30000.0 [2] |
 | Indolo[2,1-b]quinazoline-6,12-dione | IC50 | 64.0 [1] |
 | Cimicoxib | IC50 | 5.0 [1], 66.0 [2], 100.0 [3] |
 | Tebufelone | IC50 | 100.0 [1] |
 | Mavacoxib | IC50 | 40.74 [1], 41.0 [2] |
 | 4-[5-(4-Amino-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 338.84 [1], 340.0 [2] |
 | 2-(4,6-Diphenethoxypyrimidin-2-ylthio)hexanoic acid | IC50 | 10.0 [1], 40000.0 [2] |
 | 4-[5-(4-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 7.94 [1], 8.0 [2] |
 | COX-2 Inhibitor I | IC50 | 650.0 [1], 4300.0 [2] |
 | 4-Desmethyl-2-methyl Celecoxib | IC50 | 69.0 [1], 69.18 [2] |
 | 1,1-Diphenyl-2-(4-mesylphenyl)-1-hexene | IC50 | 14.0 [1], 2700.0 [2] |
 | N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide | IC50 | 100000.0 [1], 263000.0 [2] |
 | 4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 120.0 [1], 120.23 [2] |
 | 4-[5-(4-Methylamino-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 15.85 [1], 16.0 [2] |
 | 1-(4-Methanesulfonyl-phenyl)-2-p-tolyl-4-trifluoromethyl-1H-imidazole | IC50 | 158.49 [1], 160.0 [2], 180.0 [3] |
 | 4-Desmethyl-3-methyl Celecoxib | IC50 | 109.65 [1], 110.0 [2] |
 | 4-[5-(4-Nitrophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide | IC50 | 2630.0 [1], 2630.27 [2] |
 | 4-[5-(3,4-Dimethoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 600.0 [1], 602.56 [2] |
 | 4-[5-(2-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 56.0 [1], 56.23 [2] |
 | 4-[5-(3,4-Dichloro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 15.0 [1], 15.14 [2] |
 | 4-[5-(2-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 57.54 [1], 58.0 [2] |
 | 4-[5-(2-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 288.4 [1], 290.0 [2] |
 | 4-[4-Chloro-5-(4-chloro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 5.25 [1], 5.3 [2] |
 | 4-(4-Methoxy-5-phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide | IC50 | 79.43 [1], 80.0 [2] |
 | 4-[3-Carbamoyl-4-chloro-5-(4-chlorophenyl)-1H-pyrazole-1-yl]benzenesulfonamide | IC50 | 1090.0 [1], 1096.48 [2] |
 | 4-[5-(4-Methoxy-3-methyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 9.3 [1], 9.33 [2] |
 | 4-(4-Cyano-5-p-tolyl-pyrazol-1-yl)-benzenesulfonamide | IC50 | 75.86 [1], 76.0 [2] |
 | 4-[5-(4-Chloro-phenyl)-4-methyl-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 21.88 [1], 22.0 [2] |
 | 4-[5-(4-Chloro-phenyl)-4-ethyl-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 28.0 [1], 28.18 [2] |
 | 4-[5-(3-Chloro-4-methylamino-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 26.92 [1], 27.0 [2] |
 | 2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole | IC50 | 170.0 [1], 280.0 [2], 281.84 [3] |
 | 4-[2-(3-Fluoro-4-methoxyphenyl)phenyl]benzenesulfonamide | IC50 | 33.0 [1], 33.11 [2] |
 | 3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic Acid | IC50 | 100000.0 [1] |
 | 1-(4-(Methylsulfonyl)phenyl]-2-phenyl-4-trifluoromethyl-1H-imidazole | IC50 | 120.0 [1], 120.23 [2], 130.0 [3] |
 | 4-[3-Cyano-5-(4-fluoro-phenyl)-pyrazol-1-yl]-benzenesulfonamide | IC50 | 338.84 [1], 340.0 [2] |
 | 1-(4-Methanesulfonyl-phenyl)-2-m-tolyl-4-trifluoromethyl-1H-imidazole | IC50 | 60.0 [1], 60.26 [2], 80.0 [3] |
 | 3-(4-Bromo-2-fluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one | IC50 | 149.97 [1], 150.0 [2] |
 | 4-[5-(2,4-Dichloro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 56.0 [1], 56.23 [2] |
 | N-(3-Phenoxy-4-pyridinyl)methanesulfonamide | IC50 | 37500.0 [1], 100000.0 [2] |
 | 6,8-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid | IC50 | 18.0 [1], 300.0 [2] |
 | 4-Chloro-5-(3-fluoro-4-methoxyphenyl)-1-(4-(methylsulfonyl)phenyl)-1H-imidazole | IC50 | 4.0 [1], 90.0 [2], 156.0 [3] |
 | 4-(4-Chloro-3-methyl-5-phenyl-pyrazol-1-yl)-benzenesulfonamide | IC50 | 28.0 [1], 28.18 [2] |
 | 4-[2-(3-Chloro-4-methoxyphenyl)phenyl]benzenesulfonamide | IC50 | 19.0 [1], 19.05 [2] |
 | 4-[2-(4-Methoxyphenyl)-1-cyclopentenyl]benzenesulfonamide | IC50 | 2.0 [1] |
 | 4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 66.0 [1], 66.07 [2] |
 | 1-(4-Chlorophenyl)-2-[4-(methylsulfonyl)phenyl]benzene | IC50 | 140.0 [1], 141.25 [2] |
 | 4-[4-Chloro-5-(4-chloro-phenyl)-3-hydroxymethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 338.84 [1], 340.0 [2] |
 | 4-[4-Bromo-5-(4-chloro-phenyl)-pyrazol-1-yl]-benzenesulfonamide | IC50 | 30.9 [1], 31.0 [2] |
 | 4-[2-(4-Fluorophenyl)phenyl]benzenesulfonamide | IC50 | 61.0 [1], 61.66 [2] |
 | 4-[2-(3-Chloro-4-fluorophenyl)phenyl]benzenesulfonamide | IC50 | 16.98 [1], 17.0 [2] |
 | 1-(4-Fluorophenyl)-4-formyl-5-methyl-2-(4-methylsulfonylphenyl)pyrrole | IC50 | 3230.0 [1], 3235.94 [2] |
 | 2-Chloro-1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]phenyl]benzene | IC50 | 360.0 [1], 363.08 [2] |
 | 4-[5-(3-Ethyl-4-methoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide | IC50 | 426.58 [1], 430.0 [2] |
 | 3-(4-Chloro-2-fluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one | IC50 | 199.99 [1], 200.0 [2] |
 | N-(3-Phenylamino-4-pyridinyl)trifluoromethanesulfonamide | IC50 | 90.0 [1] |
 | 1-(4-Fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole-3-carbonitrile | IC50 | 750.0 [1], 758.58 [2] |
 | 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R)-1-hydroxypropan-2-yl]acetamide | IC50 | 170.0 [1] |
 | 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2S)-1-hydroxypropan-2-yl]acetamide | IC50 | 270.0 [1] |
 | 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(1R)-2-hydroxy-1-phenylethyl]acetamide | IC50 | 440.0 [1] |
 | 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(1S)-2-hydroxy-1-phenylethyl]acetamide | IC50 | 85.0 [1] |
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