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Cystine/glutamate transporter Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
L-CysteineIC50116000.0 [1]
L-CysteineKi59000.0 [1]
(S)-4-CarboxyphenylglycineIC505000.0 [1], 15000.0 [2]
4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acidIC50290000.0 [1]
4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acidKi147000.0 [1]
5-Methyl-4-[(E)-C-methyl-N-(4-nitroanilino)carbonimidoyl]-1,2-oxazole-3-carboxylic acidIC50127000.0 [1]
5-Methyl-4-[(E)-C-methyl-N-(4-nitroanilino)carbonimidoyl]-1,2-oxazole-3-carboxylic acidKi60000.0 [1]
4-[(E)-N-[3,5-Bis(trifluoromethyl)anilino]-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acidIC50129000.0 [1]
4-[(E)-N-[3,5-Bis(trifluoromethyl)anilino]-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acidKi64000.0 [1]
4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-(2-naphthalen-2-ylethyl)-1,2-oxazole-3-carboxylic acidIC50225000.0 [1]
4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-(2-naphthalen-2-ylethyl)-1,2-oxazole-3-carboxylic acidKi113000.0 [1]
SulfasalazineIC5030000.0 [1]
MesalamineIC501000000.0 [1]
Quisqualic acidIC505000.0 [1]
SulfapyridineIC501000000.0 [1]
L-Homocysteic acidIC5035000.0 [1]
ErastinIC50200.0 [1]
L-Serine O-sulfateIC5026000.0 [1]
SusalimodIC5070000.0 [1]
2-Hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethynyl]benzoic acidIC5030000.0 [1]
3-Phenylethynyl-benzoic acidIC50270000.0 [1]
5-(Phenylazo)salicylic acidIC50200000.0 [1]
Imidazole ketone erastinIC5030.0 [1]
3-(5-Acetyl-2-propan-2-yloxyphenyl)-2-[[4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl]methyl]quinazolin-4-oneIC5030.0 [1]
2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-(2-piperazin-1-ylacetyl)-2-propan-2-yloxyphenyl]quinazolin-4-oneIC50100.0 [1]
2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-[2-(4-methylpiperazin-1-yl)acetyl]-2-propan-2-yloxyphenyl]quinazolin-4-oneIC50300.0 [1]
2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-(2-morpholin-4-ylacetyl)-2-propan-2-yloxyphenyl]quinazolin-4-oneIC5010.0 [1]
2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[2-propan-2-yloxy-5-[2-(4-prop-2-enylpiperazin-1-yl)acetyl]phenyl]quinazolin-4-oneIC5010.0 [1]
2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-[2-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]acetyl]-2-propan-2-yloxyphenyl]quinazolin-4-oneIC504.0 [1]
2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-(2-fluoroacetyl)-2-propan-2-yloxyphenyl]quinazolin-4-oneIC5040.0 [1]
2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[2-propan-2-yloxy-5-(2,2,2-trifluoroacetyl)phenyl]quinazolin-4-oneIC5020.0 [1]
Methyl 2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]ethynyl]benzoateIC501000000.0 [1]
2-Hydroxy-5-[(E)-2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethenyl]benzoic acidIC5070000.0 [1]
Methyl 2-hydroxy-5-[(E)-2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethenyl]benzoateIC50900000.0 [1]
2-Hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoic acidIC50700000.0 [1]
2-Hydroxy-5-(phenylethynyl)benzoic acidIC50150000.0 [1]
3-[3-Carboxy-5-[2-(1-naphthyl)ethyl]isoxazole-4-yl]-L-alanineKi117000.0 [1]
3-[3-Carboxy-5-[2-(2-naphthyl)ethyl]isoxazole-4-yl]-L-alanineKi52000.0 [1]
3-[2-[4-(Pyridin-2-ylsulfamoyl)phenyl]ethynyl]benzoic acidIC5075000.0 [1]
3-[2-[4-(Pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoic acidIC50920000.0 [1]
Methyl 2-hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoateIC501000000.0 [1]
(R)-4-CarboxyphenylglycineIC501000000.0 [1]
Piperazine ErastinIC50800.0 [1]
3-[2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-4-oxoquinazolin-3-yl]-4-propan-2-yloxybenzaldehydeIC5060.0 [1]
Items per page: 1 - 10 of 44
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References

This online tool may be cited as follows

MLA

"Quest Database™ Cystine/glutamate transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/cystine-glutamate-transporter-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Cystine/glutamate transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cystine-glutamate-transporter-inhibitors-ic50-ki.
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