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Cytidine deaminase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
ZebularineKi2000.0 [1], 2300.0 [2], 38000.0 [3]
TetrahydrouridineIC50113.0 [1]
TetrahydrouridineKi100.0 [1], 400.0 [2]
2H-1,3-Diazepin-2-one, hexahydro-1-beta-D-ribofuranosyl-Ki400.0 [1]
(4R)-1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC50340.0 [1]
(4R)-1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneKi440000.0 [1]
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-1,3-diazepan-2-oneKi40.0 [1]
3-[(3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,7-dihydro-1H-1,3-diazepin-2-oneKi25.0 [1]
CytarabineKi190000.0 [1]
UridineKi0.0 [1]
5,6-DihydrouridineKi40000.0 [1]
Diazepinone ribosideIC50101.0 [1]
4-Amino-1-[(4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methylideneoxolan-2-yl]pyrimidin-2-oneKi7690000.0 [1]
CedazuridineIC50400.0 [1]
2'-Deoxy-2'-methylidene-5-fluorocytidineKi25100000.0 [1]
4-[(3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]piperazin-2-oneKi2800.0 [1]
4-Amino-1-(3-hydroxy-5-hydroxymethyl-4-methylene-tetrahydro-furan-2-yl)-1H-pyrimidin-2-oneKi1600000.0 [1]
(4S)-1-[(2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC505000.0 [1]
(4R)-1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC50400.0 [1]
(4S)-1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC505000.0 [1]
(4R)-1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC50200.0 [1]
(4S)-1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC504000.0 [1]
1-((4R,5S)-4,5-Dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-oneKi100000.0 [1]
1-[(3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazolidin-2-oneKi300000.0 [1]
1-[(3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazepane-2,5-dioneKi9000.0 [1]
1-[(3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazocan-2-oneKi15000.0 [1]
1-[(2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dioneIC5020000.0 [1]
1-[(2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinan-2-oneIC50100000.0 [1]
1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinan-2-oneIC50100000.0 [1]
1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dioneIC5077000.0 [1]
1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dioneIC5013000.0 [1]
3-[(2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,7-dihydro-1H-1,3-diazepin-2-oneIC50237.0 [1]
3-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,7-dihydro-1H-1,3-diazepin-2-oneIC50140.0 [1]
1-[(3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC502000.0 [1]
1-[(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC502000.0 [1]
1-[(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC50400.0 [1]
3-[(2S,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,7-dihydro-1H-1,3-diazepin-2-oneIC501616.0 [1]
(4S)-1-[(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC504000.0 [1]
(4R)-1-[(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC50400.0 [1]
(4R)-1-[(3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC50200.0 [1]
(4S)-1-[(3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC505000.0 [1]
(4S)-1-[(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC505000.0 [1]
(4R)-1-[(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-oneIC50400.0 [1]
Items per page: 1 - 10 of 43
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References

This online tool may be cited as follows

MLA

"Quest Database™ Cytidine deaminase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/cytidine-deaminase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Cytidine deaminase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cytidine-deaminase-inhibitors-ic50-ki.
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