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Cytochrome P450 11B1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
FadrozoleIC509.7 [1]
MetyraponeIC5015.0 [1]
KetoconazoleIC50127.0 [1]
OsilodrostatIC502.9 [1]
5-Imidazol-1-ylmethyl-2-phenyl-pyridineIC50107.0 [1], 152.0 [2]
3-(6-Methoxynaphthalen-2-yl)pyridineIC50574.0 [1], 1577.0 [2], 2950.0 [3]
3-(Naphthalen-2-yl)pyridineIC502395.0 [1], 3449.0 [2], 5826.0 [3]
EtomidateIC500.5 [1]
AbirateroneIC501608.0 [1], 1610.0 [2]
4-[(5r)-5,6,7,8-Tetrahydroimidazo[1,5-A]pyridin-5-Yl]benzonitrileIC509.5 [1], 9.9 [2], 119.0 [3]
5-Imidazol-1-ylmethyl-2-naphthalen-1-yl-pyridineIC5042.0 [1], 68.0 [2]
6-Pyridin-3-yl-2-naphthonitrileIC50691.0 [1]
3-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-phenylamineIC50110.0 [1]
6-Pyridin-3-yl-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-oneIC50715.0 [1]
3-(1-Chloro-7-methoxy-2-naphthyl)pyridineIC50771.0 [1], 2724.0 [2]
2-Fluoro-4-(5-imidazol-1-ylmethyl-pyridin-2-yl)-phenolIC5017.0 [1]
2-Benzo[b]thiophen-3-yl-5-imidazol-1-ylmethyl-pyridineIC5040.0 [1]
2-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-phenylamineIC50101.0 [1]
3-Imidazol-1-ylmethyl-2-thiophen-2-yl-pyridineIC5016.0 [1]
2-Bromo-3-imidazol-1-ylmethyl-pyridineIC5061.0 [1]
3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridineIC50213.0 [1], 578.0 [2]
5-Imidazol-1-ylmethyl-2-thiophen-3-yl-pyridineIC50126.0 [1], 181.0 [2]
4-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-phenylamineIC50106.0 [1]
1-BenzylimidazoleIC50135.0 [1], 602.56 [2]
6-(Pyridin-3-yl)-3,4-dihydroquinolin-2(1H)-oneIC506746.0 [1]
1-(4-Chlorobenzyl)-1H-imidazoleIC50140.0 [1], 1000.0 [2]
2-Phenyl-5-(5-methyl-3-pyridinylmethyl)pyridineIC502.0 [1]
7-Benzyloxy-4-(1H-imidazol-1-ylmethyl)-2H-chromen-2-oneIC5072.0 [1]
4-[(5S)-5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrileIC5040.0 [1], 171.0 [2]
6-Pyridin-3-ylnaphthalen-2-olIC50715.0 [1], 2671.0 [2]
1-Imidazol-1-ylmethylxanthen-9-oneIC5099.1 [1]
3-[4-(Pyridin-4-ylmethyl)phenyl]anilineIC50287.0 [1]
4-[4-(Pyridin-4-ylmethyl)phenyl]benzene-1,2-diolIC501400.0 [1]
1-(5-Pyridin-3-yl-2,3-dihydroindol-1-yl)ethanoneIC502848.0 [1]
1-(Naphthalen-2-yl)-1H-imidazoleIC501052.0 [1], 1317.0 [2]
7-Pyridin-3-yl-2H-1,4-benzothiazin-3(4H)-oneIC50525.0 [1]
2-(3,4-Dimethoxy-phenyl)-5-imidazol-1-ylmethyl-pyridineIC501000.0 [1]
5-Imidazol-1-ylmethyl-2-(2-methoxy-phenyl)pyridineIC50167.0 [1]
2-(3,4-Difluoro-phenyl)-5-imidazol-1-ylmethyl-pyridineIC50329.0 [1]
5-Imidazol-1-ylmethyl-2-(4-methoxy-phenyl)pyridineIC50782.0 [1]
2-(4-Fluoro-phenyl)-5-imidazol-1-ylmethyl-pyridineIC50213.0 [1]
4-[4-(Pyridin-4-ylmethyl)phenyl]benzene-1,2-diamineIC50502.0 [1], 902.0 [2]
3-[4-(Pyridin-4-ylmethyl)phenyl]phenolIC50342.0 [1]
2-Fluoro-4-[4-(pyridin-4-ylmethyl)phenyl]phenolIC50351.0 [1], 850.0 [2]
Cyp11B2-IN-1IC50100.0 [1], 142.0 [2]
6-[Cyclopropyl(imidazol-1-yl)methyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-oneIC501.5 [1], 2.2 [2]
7-Methoxy-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-oneIC502487.0 [1], 2867.0 [2]
7-Isoquinolin-4-yl-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolineIC50407.0 [1]
9-Fluoro-7-(5-fluoropyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolineIC5029540.0 [1]
7-Phenylmethoxy-6-pyridin-3-yl-3,4-dihydro-1H-quinolin-2-oneIC5044.0 [1]
7-[5-(2-Methoxypropan-2-yl)pyridin-3-yl]-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolineIC50108.0 [1], 219.0 [2]
(3-Methoxyphenyl)-(5-pyridin-3-yl-2,3-dihydroindol-1-yl)methanoneIC502300.0 [1]
5-(Naphthalen-2-yl)-1,3-oxazoleIC50805.0 [1]
1H-Imidazole, 1-(3-methoxy-2-naphthalenyl)-IC5081.0 [1], 5015.0 [2]
3-(5-Chloro-6-methoxy-2-naphthyl)pyridineIC50569.0 [1], 2517.0 [2]
3-(1,5-Dichloro-6-methoxy-2-naphthyl)pyridineIC501545.0 [1], 4898.0 [2]
3-(6-Ethoxynaphthalen-2-yl)pyridineIC50883.0 [1], 5419.0 [2]
3-(6-Bromonaphthalen-2-yl)pyridineIC50899.0 [1], 2939.0 [2]
Methyl 6-pyridin-3-yl-2-naphthoateIC5010505.0 [1]
3-(5-Bromo-6-methoxy-2-naphthyl)pyridineIC501531.0 [1], 4481.0 [2]
4-(1-Imidazolylmethyl)pyridineIC50663.0 [1]
3-(1-Imidazolylmethyl)pyridineIC50816.0 [1]
4-(2-Naphthyl)-1H-imidazoleIC50206.0 [1], 207.0 [2]
1H-Imidazole, 1-(3,4-dihydro-2-naphthalenyl)-IC50638.0 [1], 639.0 [2]
1H-Imidazole, 1-(3,4-dihydro-6-methoxy-2-naphthalenyl)-IC50763.0 [1]
5-Imidazol-1-ylmethyl-2-naphthalen-2-yl-pyridineIC50246.0 [1]
Pyridine, 2-(3-furanyl)-5-(1H-imidazol-1-ylmethyl)-IC5076.0 [1]
2,3-Di-furan-2-yl-5-imidazol-1-ylmethyl-pyridineIC5029.0 [1]
2-(2-Fluoro-phenyl)-5-imidazol-1-ylmethyl-pyridineIC5072.0 [1]
5-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-thiophene-2-carbaldehydeIC5062.0 [1]
5-(Imidazol-1-ylmethyl)-2-thiophen-2-ylpyridineIC5075.0 [1]
3-Imidazol-1-ylmethyl-pyridine-2-carbonitrileIC50971.0 [1]
3-(1H-Inden-2-yl)pyridineIC50862.0 [1], 2391.0 [2]
3-(3,4-Dihydronaphthalen-2-yl)pyridineIC50411.0 [1], 1729.0 [2]
3-(1-Methyl-3,4-dihydronaphthalen-2-yl)pyridineIC501268.0 [1]
3-(1-Ethyl-3,4-dihydronaphthalen-2-yl)pyridineIC502117.0 [1]
3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridineIC50503.0 [1]
3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridineIC50437.0 [1], 1291.0 [2]
2-Furan-2-yl-5-imidazol-1-ylmethyl-pyridineIC50167.0 [1]
2-(3-Fluoro-phenyl)-5-imidazol-1-ylmethyl-pyridineIC50320.0 [1]
2-(5-Chloro-thiophen-2-yl)-5-imidazol-1-ylmethyl-pyridineIC50362.0 [1]
4-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-benzonitrileIC50782.0 [1]
5-Imidazol-1-ylmethyl-2,3-diphenyl-pyridineIC50362.0 [1]
3-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-benzonitrileIC50409.0 [1]
5-(Imidazol-1-ylmethyl)-2-pyridin-3-ylpyridineIC50502.0 [1]
5-(Imidazol-1-ylmethyl)-2-(6-methoxypyridin-3-yl)pyridineIC501000.0 [1]
5-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-pyrimidineIC50971.0 [1]
4-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-isoquinolineIC5095.0 [1]
5-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-2-methyl-phenylamineIC50542.0 [1]
5-(Imidazol-1-ylmethyl)-2-pyridin-4-ylpyridineIC50139.0 [1]
5-((1H-Imidazol-1-yl)methyl)-2-bromopyridineIC50500.0 [1]
3-Bromo-2-chloro-5-imidazol-1-ylmethyl-pyridineIC50168.0 [1]
4-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-benzaldehydeIC50246.0 [1]
[4-(5-Imidazol-1-ylmethyl-pyridin-2-yl)-phenyl]-diphenyl-amineIC50611.0 [1]
2-Benzo[b]thiophen-2-yl-5-imidazol-1-ylmethyl-pyridineIC50269.0 [1]
2-Benzo[b]furan-2-yl-5-imidazol-1-ylmethyl-pyridineIC50500.0 [1]
9-Fluoro-7-(5-fluoro-4-methylpyridin-3-yl)-1-methyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolineIC501424.0 [1], 4520.0 [2]
1-[4-[[2-(2-Chlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxan-5-yl]oxymethyl]phenyl]-4-methylsulfonylpiperazineIC50100.0 [1], 10000.0 [2]
Ethyl 2-[[4-[4-[[2-(2-chlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxan-5-yl]oxymethyl]phenyl]piperazine-1-carbonyl]amino]acetateIC50107.0 [1], 5800.0 [2]
1-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxan-5-yl]oxymethyl]phenyl]piperazin-1-yl]ethanoneIC5012.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Cytochrome P450 11B1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/cytochrome-p450-11b1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Cytochrome P450 11B1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cytochrome-p450-11b1-inhibitors-ic50-ki.
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