 | Quinidine | IC50 | 20.0 [1] |
| Quinidine | Ki | 9.8 [1], 40.0 [2], 43.0 [3], 60.0 [4], 80.0 [5] |
 | Yohimbine | IC50 | 8.4 [1] |
| Yohimbine | Ki | 180.0 [1] |
 | (S)-alpha-[(2R)-8-Vinylquinuclidine-2-yl]-4-quinolinemethanol | Ki | 7500.0 [1] |
 | Ajmalicine | Ki | 4.6 [1] |
 | alpha-Naphthoflavone | IC50 | 10000.0 [1] |
 | Quinine | IC50 | 1800.0 [1] |
| Quinine | Ki | 5500.0 [1], 15000.0 [2] |
 | Indinavir | IC50 | 30000.0 [1] |
 | Duloxetine | IC50 | 1000.0 [1], 1580.0 [2], 1600.0 [3], 1995.26 [4] |
 | (-)-Dimethyl-{2-[3-((R)-1-pyrazin-2-yl-ethyl)-1H-inden-2-yl]-ethyl}-amine | IC50 | 10000.0 [1], 50000.0 [2], 50500.0 [3], 51000.0 [4] |
 | 2-[(1-Hydroxycyclohexyl)methylamino]-1-[(1R)-6-methoxy-1-propan-2-yl-3,4-dihydro-1H-isoquinolin-2-yl]ethanone | IC50 | 2900.0 [1], 37000.0 [2], 41000.0 [3], 50000.0 [4] |
 | Quercetin | IC50 | 18800.0 [1], 20000.0 [2] |
 | CID 57345320 | IC50 | 320.0 [1] |
 | Hydrocinchonine | Ki | 1600.0 [1], 2800.0 [2], 3200.0 [3] |
 | Auglurant | IC50 | 30000.0 [1], 200000.0 [2] |
 | 1-[(1R,2S)-2-[[(3S)-3-[(4-Fluorophenyl)methyl]piperidin-1-yl]methyl]cyclohexyl]-3-[3-(1-methyltetrazol-5-yl)phenyl]urea | IC50 | 30.0 [1], 200.0 [2], 210.0 [3] |
 | 1-((1R,2S)-2-(((S)-3-(4-Fluorobenzyl)piperidin-1-yl)methyl)cyclohexyl)-3-(3-acetylphenyl)urea | IC50 | 30.0 [1], 40.0 [2], 60.0 [3] |
 | N,N-Dimethyl-2-[3-(pyrazin-2-ylmethyl)-1H-inden-2-yl]ethanamine | IC50 | 6679.0 [1], 6700.0 [2], 6800.0 [3] |
 | Benzo[B]thiophene-2-ethanamine, N,N-dimethyl-3-[(1R)-1-(2-pyridinyl)ethyl]- | IC50 | 28000.0 [1], 28200.0 [2] |
 | Antihistamine-1 | IC50 | 5219.0 [1], 5400.0 [2] |
 | 4-[4-[2-[(3S)-3-Hydroxy-1-azabicyclo[2.2.2]octan-3-yl]ethynyl]phenoxy]-N-(pyrimidin-4-ylmethyl)benzamide | IC50 | 10000.0 [1], 50118.72 [2] |
 | (R)-(5-Ethyl-1-azabicyclo[2.2.2]octan-2-yl)-quinolin-4-ylmethanol | Ki | 8000.0 [1], 9600.0 [2], 24000.0 [3] |
 | Propranolol | IC50 | 1900.0 [1], 5011.87 [2] |
 | Verapamil | IC50 | 30000.0 [1], 43300.0 [2] |
 | Chlorpromazine | IC50 | 1490.0 [1] |
| Chlorpromazine | Ki | 7000.0 [1] |
 | Haloperidol | IC50 | 3640.0 [1], 30000.0 [2] |
 | Metoprolol | IC50 | 24000.0 [1], 50000.0 [2] |
 | Quinidine sulfate dihydrate | IC50 | 20.0 [1] |
 | Linezolid | IC50 | 20000.0 [1] |
 | Sertraline | IC50 | 1400.0 [1], 2880.0 [2] |
 | Nicardipine | IC50 | 1590.0 [1], 1780.0 [2] |
 | Pentamidine | IC50 | 24800.0 [1] |
 | Nortriptyline | IC50 | 2300.0 [1], 2600.0 [2] |
 | Atomoxetine | IC50 | 2000.0 [1] |
 | Dextromethorphan | IC50 | 1800.0 [1], 3400.0 [2] |
 | Fluvoxamine | Ki | 8000.0 [1], 17000.0 [2] |
 | Cinacalcet | IC50 | 50.0 [1], 100.0 [2] |
 | Amsacrine | IC50 | 10200.0 [1] |
| Amsacrine | Ki | 7500.0 [1] |
 | 4-[(7-Chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;hydrochloride | IC50 | 6100.0 [1] |
 | Mibefradil | IC50 | 63.0 [1], 840.0 [2] |
 | Bepridil | IC50 | 30000.0 [1], 50000.0 [2] |
 | Dolutegravir | IC50 | 100000.0 [1] |
 | Daclatasvir | IC50 | 100000.0 [1] |
 | Saxagliptin | IC50 | 50000.0 [1] |
 | Ivacaftor | IC50 | 20000.0 [1] |
 | 6-Chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline | IC50 | 100000.0 [1] |
 | Shogaol | IC50 | 87000.0 [1], 100000.0 [2] |
 | Pleconaril | IC50 | 1258.93 [1], 50118.72 [2] |
 | Cinchonine | IC50 | 1800.0 [1] |
| Cinchonine | Ki | 21000.0 [1] |
 | Traxoprodil | IC50 | 4250.0 [1], 10000.0 [2] |
 | Desethylamodiaquine | IC50 | 6400.0 [1] |
 | N-Hydroxy-N'-(4-butyl-2-methylphenyl)formamidine | IC50 | 83900.0 [1], 84500.0 [2] |
 | (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine | IC50 | 1600.0 [1], 1640.0 [2] |
 | S1RA | IC50 | 10000.0 [1] |
 | Bms-536924 | IC50 | 40000.0 [1] |
 | Paradol | IC50 | 30000.0 [1] |
 | N-[4-(4-Chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide | IC50 | 30000.0 [1] |
 | Temsavir | IC50 | 25000.0 [1], 40000.0 [2] |
 | 1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane | IC50 | 780.0 [1], 7000.0 [2] |
 | (8)-Gingerol | IC50 | 42700.0 [1], 74500.0 [2] |
 | MK-7246 | IC50 | 30000.0 [1], 100000.0 [2] |
 | 4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine | IC50 | 660.0 [1], 1000.0 [2] |
 | (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile | IC50 | 200000.0 [1] |
 | 4-(8-Fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide | IC50 | 1600.0 [1], 25000.0 [2] |
 | Isoquine | IC50 | 7000.0 [1] |
 | (S)-7-Hydroxy-2-(4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl)-8-(3-methylbut-2-en-1-yl)chroman-4-one | IC50 | 20000.0 [1] |
 | 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide | IC50 | 100000.0 [1] |
 | SB 221284 | IC50 | 110.0 [1] |
 | 2,3-Dimethyl-8-(2-ethyl-6-methylbenzylamino)-imidazo[1,2-a]pyridine-6-carboxamide | IC50 | 9200.0 [1] |
 | Unii-pon9ofp69G | IC50 | 2600.0 [1] |
| Unii-pon9ofp69G | Ki | 2600.0 [1] |
 | N-[2-(Diethylamino)ethyl]-2-[2-[(4-fluorophenyl)methylsulfanyl]-5-[(1-methylpyrazol-4-yl)methyl]-4-oxopyrimidin-1-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide | IC50 | 37000.0 [1] |
 | 4-Methoxy-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide | IC50 | 30000.0 [1] |
 | N-(4-(Trifluoromethyl)oxazol-2-yl)-9H-xanthene-9-carboxamide | IC50 | 30000.0 [1] |
 | (3R)-N-Isoquinolin-3-ylspiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine | IC50 | 40000.0 [1] |
 | 2-(2-(4-Tert-Butylphenylthio)ethyl)-1H-imidazole | IC50 | 680.0 [1] |
 | CID 46244454 | IC50 | 10000.0 [1] |
 | 1-Cyclohexyl-2-(furan-3-yl)-N-[(1S)-2-(5-hydroxy-1H-indol-3-yl)-1-(1,3-thiazol-4-yl)ethyl]benzimidazole-5-carboxamide | IC50 | 4000.0 [1] |
 | 3-(1-Naphthyl)-1-(4-pyridinyl)-2-propen-1-one | IC50 | 10000.0 [1], 18000.0 [2] |
 | 5-(4-Chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide | IC50 | 20000.0 [1] |
 | (E)-3-(2-Chlorophenyl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one | IC50 | 10000.0 [1], 12000.0 [2] |
 | Benzamide, 2,3-dichloro-N-(2-methylpropyl)-N-(3S)-3-pyrrolidinyl- | IC50 | 30000.0 [1] |
 | 1-Cyano-3-(2-methyl-1-benzofuran-5-yl)-2-[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]guanidine | IC50 | 40000.0 [1], 200000.0 [2] |
 | 2-(2-Amino-1,3-thiazol-4-yl)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]acetamide | IC50 | 2200.0 [1] |
 | Bms-344577 | IC50 | 40000.0 [1], 200000.0 [2] |
 | 2-(4-Fluorophenyl)-N-[6-methoxy-5-(4-methylimidazol-1-yl)pyridin-2-yl]-1-methylbenzimidazol-4-amine | IC50 | 3600.0 [1] |
 | (2S)-2-[2-Methyl-4-(2-oxa-8-azatricyclo[7.3.1.05,13]trideca-1(13),5,7,9,11-pentaen-10-yl)quinolin-3-yl]-2-[(2-methylpropan-2-yl)oxy]acetic acid | IC50 | 30000.0 [1] |
 | N-[4-[(1R,2R)-2-(Dimethylamino)-1-imidazol-1-ylpropyl]phenyl]-1,3-benzothiazol-2-amine | IC50 | 3900.0 [1] |
 | Linaprazan | IC50 | 46000.0 [1], 58000.0 [2] |
 | (5-Pyrid-3-ylthien-2-YL)methylamine | IC50 | 168000.0 [1] |
| (5-Pyrid-3-ylthien-2-YL)methylamine | Ki | 84500.0 [1] |
 | (5-(Pyridin-3-YL)furan-2-YL)methanamine | IC50 | 11300.0 [1] |
| (5-(Pyridin-3-YL)furan-2-YL)methanamine | Ki | 5700.0 [1] |
 | (S)-N-(2,3-Dichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide | IC50 | 3000.0 [1], 27100.0 [2] |
 | 3-[(E)-[3-[(E)-2-[4-[(Dimethylamino)methyl]phenyl]ethenyl]indazol-6-ylidene]methyl]-1H-indol-2-ol | IC50 | 8900.0 [1], 9000.0 [2] |
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