Name: Dihydrofolate reductase Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Dihydrofolate reductase Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	Methotrexate	IC50	20.0 ^[1]
	Methotrexate	Ki	0.01 ^[1]
	Trimethoprim	IC50	198000.0 ^[1]
	Trimethoprim	Ki	1380.0 ^[1]
	Pemetrexed	IC50	6600.0 ^[1]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Dihydrofolate reductase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 2 Jan. 2026, https://www.aatbio.com/data-sets/dihydrofolate-reductase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2026, January 2). Quest Database™ Dihydrofolate reductase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dihydrofolate-reductase-inhibitors-ic50-ki.
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