DNA topoisomerase II beta Inhibitors (IC50, Ki)

Name: DNA topoisomerase II beta Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Doxorubicin	IC50	3500.0 ^[1]
	Etoposide	IC50	69.8 ^[1], 790.0 ^[2]
	Amsacrine	IC50	2760.0 ^[1]
	[2,4-Dibromo-6-[(E)-3-(2-carbamothioylhydrazinyl)-3-oxo-2-[(3,4,5-trimethoxybenzoyl)amino]prop-1-enyl]phenyl] acetate	IC50	81.42 ^[1]
	[2,4-Dibromo-6-[(Z)-[6-oxo-2-phenyl-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazin-5-ylidene]methyl]phenyl] acetate	IC50	12.6 ^[1]
	[2,4-Dibromo-6-[(Z)-[1-methyl-8-oxo-3-sulfanylidene-5-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[1,2-a][1,2,4]triazin-7-ylidene]methyl]phenyl] acetate	IC50	110.45 ^[1]
	[2,4-Dibromo-6-[(Z)-[6-oxo-2-(5-phenyl-1,3-thiazol-2-yl)-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazin-5-ylidene]methyl]phenyl] acetate	IC50	6.85 ^[1]
	[2,4-Dibromo-6-[(Z)-[2-carbamothioyl-6-oxo-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazin-5-ylidene]methyl]phenyl] acetate	IC50	31.68 ^[1]
	1-Cyclopropyl-6-fluoro-7-[4-[2-[(2E)-2-[(2-hydroxyphenyl)methylidene]hydrazinyl]-2-oxoethyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid	IC50	580.0 ^[1]
	1-Cyclopropyl-6-fluoro-7-[4-[2-[(2E)-2-(1H-indol-2-ylmethylidene)hydrazinyl]-2-oxoethyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acid	IC50	860.0 ^[1]
	1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[4-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-ylamino)phenyl]urea	IC50	9290.0 ^[1]
	Ethyl 7-[4-[4-[(5S)-5-(acetamidomethyl)-2-oxo-1,3-oxazolidin-3-yl]-2-fluorobenzoyl]piperazin-1-yl]-1-ethyl-6-fluoro-4-oxoquinoline-3-carboxylate	IC50	12500.0 ^[1]

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References

MLA	"Quest Database™ DNA topoisomerase II beta Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/dna-topoisomerase-ii-beta-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ DNA topoisomerase II beta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dna-topoisomerase-ii-beta-inhibitors-ic50-ki.
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