 | Cocaine | IC50 | 301.0 [1] |
| Cocaine | Ki | 330.0 [1] |
 | Duloxetine | IC50 | 870.0 [1] |
| Duloxetine | Ki | 240.0 [1], 251.19 [2], 370.0 [3], 435.0 [4], 240000.0 [5] |
 | Fluoxetine | IC50 | 6000.0 [1] |
| Fluoxetine | Ki | 1900.0 [1], 6000.0 [2], 6670.0 [3] |
 | Mazindol | IC50 | 13.0 [1], 22.0 [2], 43.0 [3] |
| Mazindol | Ki | 22.1 [1], 34.6 [2], 45.0 [3], 74.2 [4] |
 | Vanoxerine | IC50 | 27.0 [1] |
| Vanoxerine | Ki | 0.36 [1], 3.7 [2], 5.07 [3], 22.0 [4] |
 | Bupropion | IC50 | 945.0 [1] |
| Bupropion | Ki | 441.0 [1], 821.4 [2], 871.0 [3] |
 | Methyl (1R,2S,3S,5R)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | IC50 | 11.0 [1], 21.0 [2] |
| Methyl (1R,2S,3S,5R)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | Ki | 10.6 [1], 14.7 [2] |
 | Nomifensine | IC50 | 15.0 [1], 30.2 [2], 31.62 [3], 281.84 [4] |
| Nomifensine | Ki | 10.0 [1], 23.5 [2], 79.0 [3], 84.0 [4] |
 | Venlafaxine | IC50 | 4430.0 [1], 7340.0 [2], 9120.11 [3], 15767.0 [4] |
| Venlafaxine | Ki | 890.0 [1], 5300.0 [2] |
 | 1-[1-(1-Benzothiophen-2-yl)cyclohexyl]piperidine | IC50 | 12.0 [1] |
| 1-[1-(1-Benzothiophen-2-yl)cyclohexyl]piperidine | Ki | 2.2 [1], 6.2 [2] |
 | Methyl (2S,3S,5R)-8-methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylate;hydrochloride | IC50 | 23.0 [1], 65.0 [2], 373.0 [3] |
| Methyl (2S,3S,5R)-8-methyl-3-phenyl-8-azabicyclo[3.2.1]octane-2-carboxylate;hydrochloride | Ki | 33.0 [1], 314.0 [2] |
 | Desipramine | IC50 | 9900.0 [1], 17700.0 [2], 47900.0 [3], 50500.0 [4], 82000.0 [5] |
| Desipramine | Ki | 0.49 [1], 3000.0 [2] |
 | Atomoxetine | IC50 | 3000.0 [1] |
 | Nisoxetine | IC50 | 1150.0 [1], 2400.0 [2] |
| Nisoxetine | Ki | 30.0 [1], 1000.0 [2] |
 | Modafinil | IC50 | 11500.0 [1] |
| Modafinil | Ki | 927.0 [1], 1456.0 [2], 2000.0 [3], 3090.0 [4], 13000.0 [5] |
 | 2-[(2-Ethoxyphenoxy)-phenylmethyl]morpholine | IC50 | 25000.0 [1] |
| 2-[(2-Ethoxyphenoxy)-phenylmethyl]morpholine | Ki | 60.0 [1], 10000.0 [2] |
 | Midalcipran | IC50 | 6100.0 [1], 10000.0 [2] |
| Midalcipran | Ki | 854.0 [1], 31622.78 [2] |
 | 1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane | IC50 | 78.0 [1], 93.8 [2], 394.0 [3] |
| 1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane | Ki | 251.0 [1] |
 | Rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-azabicyclo[4.1.0]heptane | IC50 | 2.0 [1], 8.0 [2] |
| Rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-azabicyclo[4.1.0]heptane | Ki | 10.0 [1], 12.02 [2], 25.12 [3] |
 | (R)-3-Benzoyloxy-2-methoxycarbonyl-8-methyl-8-azonia-bicyclo[3.2.1]octane | IC50 | 350.0 [1], 470.0 [2], 490.0 [3], 717.0 [4], 1161.0 [5] |
 | 6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,1-a]isoindol-6-ol | IC50 | 3.7 [1], 4.2 [2] |
| 6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,1-a]isoindol-6-ol | Ki | 1.7 [1] |
 | Methylphenidate | IC50 | 17.0 [1], 79.0 [2] |
| Methylphenidate | Ki | 34.0 [1], 110.0 [2] |
 | Vanoxerine dihydrochloride | IC50 | 14.0 [1], 190.0 [2] |
| Vanoxerine dihydrochloride | Ki | 2.42 [1] |
 | Dexmethylphenidate | IC50 | 88.0 [1], 156.0 [2] |
| Dexmethylphenidate | Ki | 16.0 [1], 25.0 [2] |
 | Madam | IC50 | 100.0 [1] |
| Madam | Ki | 532.0 [1], 1000.0 [2], 10000.0 [3] |
 | Pyrovalerone | IC50 | 32.0 [1], 52.0 [2] |
| Pyrovalerone | Ki | 8.0 [1], 21.4 [2] |
 | Amitifadine | IC50 | 96.0 [1], 159.3 [2] |
| Amitifadine | Ki | 79.43 [1], 125.89 [2] |
 | 3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester | IC50 | 1.4 [1], 1.7 [2], 2.4 [3] |
| 3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester | Ki | 1.1 [1] |
 | 3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester | IC50 | 1.3 [1] |
| 3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester | Ki | 0.48 [1], 1.3 [2] |
 | Methyl 3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | IC50 | 0.38 [1], 0.4 [2], 1.09 [3] |
 | 3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester | IC50 | 1.1 [1] |
| 3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester | Ki | 0.2 [1], 2.3 [2] |
 | (R)-Sila-Venlafaxine | IC50 | 4900.0 [1], 5270.0 [2] |
 | 4-(3,4-Dimethoxy-phenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one | IC50 | 100000.0 [1] |
| 4-(3,4-Dimethoxy-phenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one | Ki | 100000.0 [1] |
 | (S)-N-(2,3-Dimethylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine | IC50 | 727.0 [1] |
 | (1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-(ethoxymethyl)-3-azabicyclo[3.1.0]hexane | IC50 | 5.01 [1] |
| (1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-(ethoxymethyl)-3-azabicyclo[3.1.0]hexane | Ki | 7.94 [1], 25.12 [2] |
 | 2-[5-[3-(5-Fluoro-2-methoxyphenyl)propyl]oxolan-2-yl]ethanamine | IC50 | 16987.0 [1], 41260.0 [2] |
| 2-[5-[3-(5-Fluoro-2-methoxyphenyl)propyl]oxolan-2-yl]ethanamine | Ki | 7307.0 [1], 21190.0 [2] |
 | Dimethyl-((2S,3S)-3-naphthalen-2-yl-bicyclo[2.2.1]hept-2-ylmethyl)-amine | IC50 | 76.0 [1] |
| Dimethyl-((2S,3S)-3-naphthalen-2-yl-bicyclo[2.2.1]hept-2-ylmethyl)-amine | Ki | 25.0 [1] |
 | Methyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate | Ki | 1900.0 [1], 5500.0 [2], 512861383991366.0 [3] |
 | (cis)-2-(5-Bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one | IC50 | 100000.0 [1] |
| (cis)-2-(5-Bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one | Ki | 100000.0 [1] |
 | 3-(4-Chloro-phenyl)-2-(2-chloro-vinyl)-8-methyl-8-aza-bicyclo[3.2.1]octane | IC50 | 0.73 [1], 1.3 [2] |
| 3-(4-Chloro-phenyl)-2-(2-chloro-vinyl)-8-methyl-8-aza-bicyclo[3.2.1]octane | Ki | 0.22 [1], 0.88 [2] |
 | Cocaine hydrochloride | IC50 | 89.1 [1] |
| Cocaine hydrochloride | Ki | 46.3 [1] |
 | 3,4-Methylenedioxymethamphetamine | IC50 | 1442.0 [1], 2398.83 [2] |
 | Sertraline | IC50 | 310.0 [1] |
| Sertraline | Ki | 25.8 [1] |
 | Tenamfetamine | IC50 | 890.0 [1], 6165.95 [2] |
 | Benztropine | IC50 | 312.0 [1] |
| Benztropine | Ki | 193.0 [1] |
 | 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine;hydrochloride | IC50 | 1.7 [1], 5.0 [2] |
| 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine;hydrochloride | Ki | 16.2 [1] |
 | 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine | IC50 | 18.0 [1] |
| 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine | Ki | 3.7 [1], 73.0 [2] |
 | Reboxetine | IC50 | 10000.0 [1] |
| Reboxetine | Ki | 2000.0 [1], 19952.62 [2] |
 | 2-((2-((Dimethylamino)methyl)phenyl)thio)-5-iodophenylamine | Ki | 840.0 [1], 10000.0 [2] |
 | Benzonitrile, 3-amino-4-((2-((dimethylamino)methyl)phenyl)thio)- | Ki | 1000.0 [1], 1423.0 [2], 10000.0 [3] |
 | N,N-Diallyl-5-methoxytryptamine | IC50 | 32359.37 [1] |
| N,N-Diallyl-5-methoxytryptamine | Ki | 3162.28 [1], 10000.0 [2] |
 | Methyl (3S,5R)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | IC50 | 1.1 [1], 1.7 [2], 3.2 [3] |
 | (S)-Venlafaxine | IC50 | 4430.0 [1], 6670.0 [2] |
 | 3-Amino-4-[[2-[(dimethylamino)methyl]phenyl]thio]benzenemethanol | Ki | 1000.0 [1], 3608.0 [2] |
 | BMS-505130 free base | IC50 | 4200.0 [1] |
| BMS-505130 free base | Ki | 2100.0 [1] |
 | 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindole | IC50 | 6.0 [1], 29.7 [2] |
| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindole | Ki | 23.0 [1] |
 | (1S,5R)-1-(3,4-Dichlorophenyl)-3-azabicyclo(3.1.0)hexane | IC50 | 129.0 [1] |
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