Name: Dual specificity mitogen-activated protein kinase kinase; MEK1/2 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Dual specificity mitogen-activated protein kinase kinase; MEK1/2 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide	IC50	16.0 ^[1], 46.0 ^[2]
	3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)benzamide	IC50	1.2 ^[1], 2.0 ^[2]
	4-(2-Fluoro-4-iodoanilino)-1-methyl-6-oxopyridine-3-carboxamide	IC50	4.0 ^[1], 23.0 ^[2]
	3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide	IC50	17.4 ^[1], 30.0 ^[2]
	4-(2-Fluoro-4-iodoanilino)-6-oxo-1-propylpyridine-3-carboxamide	IC50	430.0 ^[1], 2540.0 ^[2]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Dual specificity mitogen-activated protein kinase kinase; MEK1/2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 15 Dec. 2025, https://www.aatbio.com/data-sets/dual-specificity-mitogen-activated-protein-kinase-kinase-mek1-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 15). Quest Database™ Dual specificity mitogen-activated protein kinase kinase; MEK1/2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dual-specificity-mitogen-activated-protein-kinase-kinase-mek1-2-inhibitors-ic50-ki.
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