Dual-specificity tyrosine-phosphorylation regulated kinase 1A Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Harmine	IC50	56.0 [1]
	Harmine	Ki	33.0 [1]
	Seliciclib	IC50	3100.0 [1]
	(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one	IC50	830.0 [1]
	Leucettine L41	IC50	21.0 [1], 55.0 [2], 60.0 [3]
	2-(4-Fluorophenyl)-N-[5-(4-pyridin-3-ylthiophen-2-yl)pyridin-3-yl]acetamide	IC50	14.3 [1], 79.0 [2]
	(-)-Epigallocatechin gallate	IC50	330.0 [1], 13440.0 [2]
	(1z)-1-(3-Ethyl-5-Hydroxy-1,3-Benzothiazol-2(3h)-Ylidene)propan-2-One	IC50	240.0 [1]
	4,5,6,7-Tetrabromobenzotriazole	IC50	1000.0 [1], 4360.0 [2]
	4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine	IC50	120.0 [1], 400.0 [2]
	5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione	IC50	30.0 [1], 1600.0 [2]
	O6-Cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine	IC50	900.0 [1]
	Leucettamine B	IC50	600.0 [1], 950.0 [2]
	6-(1,3-Benzodioxol-5-yl)-N-(thiophen-2-ylmethyl)-4-quinazolinamine	IC50	27.0 [1], 62.0 [2]
	Paprotrain	IC50	5500.0 [1]
	CID 46926514	IC50	282.0 [1], 2600.0 [2]
	CID 71529770	IC50	1.13 [1]
	Ethyl 3-[(E)-2-Amino-1-Cyanoethenyl]-6,7-Dichloro-1-Methyl-1h-Indole-2-Carboxylate	IC50	55.0 [1]
	CID 71529752	IC50	0.16 [1], 3.6 [2]
	1-Methyl-7-(pyridin-3-ylmethoxy)-9H-pyrido[3,4-b]indole	IC50	10000.0 [1]
	7-(2-Methoxyethoxy)-1-methyl-9H-pyrido[3,4-b]indole	IC50	15500.0 [1], 16000.0 [2]
	1-(6-Oxo-2,3,4,10b-tetrahydro-1H-pyrido[2,1-a]isoindol-10-yl)-3-pyridin-2-ylurea	IC50	10000.0 [1]
	(7-Methoxy-9H-pyrido[3,4-b]indol-1-yl)methanol	IC50	54.8 [1], 106.0 [2]
	5-(4-Pyridin-3-ylthiophen-2-yl)pyridin-3-amine	IC50	101.0 [1]
	3-(4-Pyridin-3-ylthiophen-2-yl)pyridine	IC50	300.0 [1]
	CID 46926513	IC50	4.0 [1], 50.0 [2]
	1-Methyl-7-cyclohexylmethyloxy-9-cyclohexylmethyl-beta-carboline	IC50	10000.0 [1]
	1-(6-Oxo-2,3,4,10b-tetrahydro-1H-pyrido[2,1-a]isoindol-10-yl)-3-pyrazin-2-ylurea	IC50	10000.0 [1]
	Methyl 9-(2-bromo-4-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	0.16 [1], 3.6 [2]
	1-Methyl-7-benzyloxy-9-benzyl-beta-carboline	IC50	16000.0 [1], 16300.0 [2]
	(5Z)-5-(Quinolin-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	20.0 [1], 1400.0 [2]
	(3E)-3-(2,3-Dihydro-1-benzofuran-5-ylmethylidene)-5-methyloxolan-2-one	IC50	170.0 [1], 2100.0 [2]
	(5Z)-5-(1,3-Benzothiazol-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	40.0 [1], 2100.0 [2]
	(3E)-3-(1,3-Benzothiazol-6-ylmethylidene)oxolan-2-one	IC50	130.0 [1], 200.0 [2]
	Methyl 9-(3-fluoro-4-hydroxyanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	8.63 [1]
	Methyl 9-(4-hydroxy-3-nitroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	4.91 [1]
	4-[5-(4-Aminophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenol	IC50	43.0 [1], 711.0 [2]
	5-(1,3-Benzodioxol-5-yl)-N-(pyridin-3-ylmethyl)pyrimidin-4-amine	IC50	10000.0 [1], 26020.0 [2]
	N-[(3,4-Dichlorophenyl)methyl]-4-(3-methoxyphenyl)pyrimidin-2-amine	IC50	4654.0 [1], 5820.0 [2]
	N-[(4-Chlorophenyl)methyl]-4-(3-methoxyphenyl)pyrimidin-2-amine	IC50	6361.0 [1], 7330.0 [2]
	N-[(3,4-Dichlorophenyl)methyl]-4-(4-methoxyphenyl)pyrimidin-2-amine	IC50	203.0 [1], 1160.0 [2]
	N-[(4-Chlorophenyl)methyl]-4-(4-methoxyphenyl)pyrimidin-2-amine	IC50	558.0 [1], 2070.0 [2]
	4-(1,3-Benzodioxol-5-yl)-N-[3-bromo-5-(trifluoromethyl)phenyl]pyrimidin-2-amine	IC50	107.0 [1], 520.0 [2]
	4-(1,3-Benzodioxol-5-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidin-2-amine	IC50	10.0 [1], 70.0 [2]
	4-(1,3-Benzodioxol-5-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amine	IC50	7.0 [1], 40.0 [2]
	N-[(3,4-Dichlorophenyl)methyl]-4-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimidin-2-amine	IC50	18.0 [1], 210.0 [2]
	5-(1,3-Benzodioxol-5-yl)-N-[(3,4-dichlorophenyl)methyl]pyrimidin-4-amine	IC50	3454.0 [1], 4120.0 [2]
	N,4-Bis(1,3-benzodioxol-5-yl)pyrimidin-2-amine	IC50	25.0 [1], 130.0 [2]
	4-(1,3-Benzodioxol-5-yl)-N-[(3,5-dibromophenyl)methyl]pyrimidin-2-amine	IC50	11.0 [1], 70.0 [2]
	4-(1,3-Benzodioxol-5-yl)-N-[(3,4-dichlorophenyl)methyl]pyrimidin-2-amine	IC50	26.0 [1], 160.0 [2]
	5-(1,3-Benzodioxol-5-yl)-N-[(4-chlorophenyl)methyl]pyrimidin-4-amine	IC50	4579.0 [1], 26020.0 [2]
	4-(1,3-Benzodioxol-5-yl)-N-(4-chlorophenyl)pyrimidin-2-amine	IC50	273.0 [1], 520.0 [2]
	4-(1,3-Benzodioxol-5-yl)-N-[(3,4-dibromophenyl)methyl]pyrimidin-2-amine	IC50	79.0 [1], 820.0 [2]
	N-[(3,4-Dichlorophenyl)methyl]-4-(1H-indazol-6-yl)pyrimidin-2-amine	IC50	169.0 [1], 1640.0 [2]
	N-[(3,4-Dichlorophenyl)methyl]-2-(1H-indazol-5-yl)pyrimidin-4-amine	IC50	2352.0 [1], 4630.0 [2]
	2-(1H-Indazol-6-yl)-N-(pyridin-3-ylmethyl)pyrimidin-4-amine	IC50	1434.0 [1], 2070.0 [2]
	4-(1H-Indazol-5-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amine	IC50	61.0 [1], 150.0 [2]
	N-[(3,4-Dichlorophenyl)methyl]-4-(1H-indazol-5-yl)pyrimidin-2-amine	IC50	129.0 [1], 330.0 [2]
	2-(1H-Indazol-5-yl)-N-(pyridin-3-ylmethyl)pyrimidin-4-amine	IC50	349.0 [1], 650.0 [2]
	Methyl 9-(2,4-dichloroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboxylate	IC50	5.1 [1]
	9-(4-Bromo-2-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboxamide	IC50	194.4 [1]
	9-(2-Bromo-4-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboxamide	IC50	26.2 [1]
	Methyl 9-(3,4,5-trimethoxyanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	436.1 [1]
	Methyl 9-(2,4-dimethoxyanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	9.53 [1]
	Methyl 9-anilino-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	1.81 [1]
	Methyl 9-(4-methylanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	0.98 [1]
	Methyl 9-(4-fluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	6.06 [1]
	Methyl 9-(3-cyanoanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	42.7 [1]
	Methyl 9-(4-cyanoanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	3.89 [1]
	Methyl 9-(2,4-dichloroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	0.22 [1]
	Methyl 9-(4-tert-butylanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	39.03 [1]
	Methyl 9-(3-chloroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	13.64 [1]
	Methyl 9-[4-(dimethylamino)anilino]-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	35.64 [1]
	Methyl 9-(2,4-difluoroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	0.94 [1]
	Methyl 9-[4-(trifluoromethyl)anilino]-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	18.26 [1]
	Ethyl 9-(1,3-benzodioxol-5-ylamino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	6.02 [1]
	Benzyl 9-(1,3-benzodioxol-5-ylamino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	33.93 [1]
	9-(1,3-Benzodioxol-5-ylamino)-N'-[2-(dimethylamino)ethyl]-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidamide	IC50	431.2 [1]
	Methyl 9-(4-methoxyanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	13.08 [1]
	Methyl 9-(1,3-benzodioxol-5-ylamino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate	IC50	1.65 [1]
	10-Iodo-11h-Indolo[3,2-C]quinoline-6-Carboxylic Acid	IC50	6.0 [1], 500.0 [2]
	2,9-Dibenzyl-1-methyl-7-phenylmethoxypyrido[3,4-b]indol-2-ium	IC50	21000.0 [1], 21200.0 [2]
	2-Benzyl-7-(cyclohexylmethoxy)-9-(cyclohexylmethyl)-1-methylpyrido[3,4-b]indol-2-ium	IC50	43000.0 [1]
	Staurosporine	IC50	19.0 [1]
	Ellagic acid	IC50	40000.0 [1]
	6-Bromoindirubin-3'-oxime	IC50	52.0 [1]
	Silmitasertib	IC50	6.8 [1]
	Harmol	IC50	90.0 [1]
	Purvalanol A	IC50	300.0 [1]
	4,5,6,7-Tetrabromobenzimidazole	IC50	2100.0 [1]
	1,4-Diaminoanthraquinone	IC50	3600.0 [1]
	4-(1H-Indol-3-yl)pyrimidin-2-amine	IC50	588.0 [1]
	4-[1-Ethyl-7-[(piperidin-4-ylamino)methyl]imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine	IC50	4900.0 [1]
	JNK Inhibitor VIII	Ki	6900.0 [1]
	(5-Oxo-5,6-dihydro-indolo[1,2-A]quinazolin-7-YL)-acetic acid	IC50	8000.0 [1]
	(2S,3S)-3-((7-(Benzylamino)-3-isopropylpyrazolo[1,5-a]pyrimidin-5-yl)amino)butane-1,2,4-triol	IC50	2100.0 [1]
	4-(Pyridin-3-ylmethylene)-2-styryloxazol-5(4H)-one	IC50	10000.0 [1]
	Butyrolactonei	IC50	100000.0 [1]
	3-(4-Methoxy-benzylidene)-dihydro-furan-2-one	IC50	1810.0 [1]
	6-(3-Methoxyphenyl)-N-(thiophen-2-ylmethyl)-4-quinazolinamine	IC50	5697.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Dual-specificity tyrosine-phosphorylation regulated kinase 1A Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/dual-specificity-tyrosine-phosphorylation-regulated-kinase-1a-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Dual-specificity tyrosine-phosphorylation regulated kinase 1A Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dual-specificity-tyrosine-phosphorylation-regulated-kinase-1a-inhibitors-ic50-ki.
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