Dual specificty protein kinase CLK1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Harmine	IC50	26.0 [1], 72.0 [2], 220.0 [3]
	(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one	IC50	17.0 [1], 49.0 [2], 170.0 [3]
	6-Bromoindirubin-3'-oxime	IC50	2100.0 [1]
	Kenpaullone	IC50	10000.0 [1]
	5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione	IC50	70.0 [1]
	9H-Purine-2,6-diamine, N2-(2-aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-, cis-	IC50	148.0 [1]
	Paullone	IC50	10000.0 [1]
	4-(1H-Indol-3-yl)pyrimidin-2-amine	IC50	530.0 [1]
	Leucettine L41	IC50	71.0 [1]
	N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine	IC50	7600.0 [1]
	4-(5-Bromo-1H-indol-3-yl)pyrimidin-2-amine	IC50	220.0 [1]
	Cdk1/2 Inhibitor III	IC50	8.9 [1]
	6,7-Dimethoxy-N-phenylquinazolin-4-amine	IC50	10000.0 [1]
	CID 53246941	IC50	512.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(thiophen-2-ylmethyl)-4-quinazolinamine	IC50	59.0 [1]
	CID 46926514	IC50	68.0 [1]
	3-(4-Methoxy-benzylidene)-dihydro-furan-2-one	IC50	10000.0 [1]
	Ethyl 3-[(E)-2-Amino-1-Cyanoethenyl]-6,7-Dichloro-1-Methyl-1h-Indole-2-Carboxylate	IC50	20.0 [1]
	6,7-Dimethoxy-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine	IC50	10000.0 [1]
	2-(3-Hydroxy-4-methoxystyryl)-8-hydroxyquinoline-7-carboxylic acid	IC50	8300.0 [1]
	4-(4-Hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1H)-one	IC50	210.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(2-furanylmethyl)-N-methyl-4-quinazolinamine	IC50	22.0 [1]
	(5Z)-5-(4-Methoxybenzylidene)imidazolidine-2,4-dione	IC50	10000.0 [1]
	3-(1,3-Benzodioxol-5-ylmethylene)dihydro-2(3H)-furanone	IC50	10000.0 [1]
	Meridianin D	IC50	120.0 [1]
	[5-[4-[(5-Methyl-2-furanyl)methylamino]-6-quinazolinyl]-2-furanyl]methanol	IC50	1522.0 [1]
	6,11-Dihydroxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one	IC50	10000.0 [1]
	Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amine	IC50	680.0 [1]
	2-(2,4-Dihydroxybenzylcarbamoyl)-8-hydroxyquinoline-7-carboxylic acid	IC50	10000.0 [1]
	2,2-Dimethyl-7-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-1-[(1R)-1-phenylethyl]-3H-quinazolin-4-one	IC50	10.0 [1]
	(4-Fluoro-3-hydroxyphenyl)-(5-hydroxy-1-benzothiophen-2-yl)methanone	IC50	300.0 [1]
	1-[5-Amino-4-(3,4-dichlorophenyl)-3-methylpyrazol-1-yl]ethanone	IC50	100000.0 [1]
	12-Phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	190.0 [1]
	N-Phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	4500.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[(2-methyl-4-thiazolyl)methyl]-4-quinazolinamine	IC50	96.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-[(2-methyl-4-thiazolyl)methyl]-4-quinazolinamine	IC50	20.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-(1,3-thiazol-2-ylmethyl)quinazolin-4-amine	IC50	28.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-(thiophen-2-ylmethyl)-4-quinazolinamine	IC50	11.0 [1]
	6-(Benzo[d][1,3]dioxol-5-yl)-N-(furan-3-ylmethyl)quinazolin-4-amine	IC50	111.0 [1]
	5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamide	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(3-oxolanylmethyl)-4-quinazolinamine	IC50	522.0 [1]
	CID 46926513	IC50	2.0 [1]
	(Z)-2-(4-Methoxy-1H-indol-3-yl)-3-pyridin-3-yl-acrylonitrile	IC50	3000.0 [1]
	(Z)-2-(6-Methoxy-1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile	IC50	1300.0 [1]
	(Z)-3-Pyridin-3-yl-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-enenitrile	IC50	16.0 [1]
	4-(7-Bromo-1H-indol-3-yl)pyrimidin-2-amine	IC50	65.0 [1]
	4-(7-Nitro-1H-indol-3-yl)pyrimidin-2-amine	IC50	70.0 [1]
	6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	10000.0 [1]
	N-(3,4-Dimethoxyphenyl)-6,7-dimethoxyquinazolin-4-amine	IC50	1500.0 [1]
	CID 71553154	IC50	1630.0 [1]
	N-(4-(6,7-Dimethoxyquinazolin-4-ylamino)phenyl)acetamide	IC50	10000.0 [1]
	(Z)-2-(7-Methoxy-1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile	IC50	1500.0 [1]
	5,17-Dihydroxy-4,4,10,10,15-pentamethyl-3,9-dioxa-15-azapentacyclo[12.8.0.02,7.08,13.016,21]docosa-1,5,7,11,13,16(21),17,19-octaen-22-one	IC50	10000.0 [1]
	6,7-Dimethoxy-N-[4-(trifluoromethyl)phenyl]quinazolin-4-amine	IC50	10000.0 [1]
	12-(2,4-Dichlorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	88.0 [1]
	12-(4-Methylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	2500.0 [1]
	12-(4-Methoxyphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	280.0 [1]
	12-(4-Chlorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	1100.0 [1]
	12-(3-Chlorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	690.0 [1]
	12-(3,4-Dichlorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	2400.0 [1]
	1-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)ethanone	IC50	10000.0 [1]
	(6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hydrochloride	IC50	10000.0 [1]
	3-(6-Chloroimidazo[1,2-a]pyridine-2-yl)benzamide	IC50	10000.0 [1]
	(5Z)-5-(Quinolin-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	200.0 [1]
	4-[[4-Cyclopentyloxy-5-(2-methyl-1,3-benzoxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methylbenzamide	IC50	300.0 [1]
	(5-Hydroxy-1-benzothiophen-2-yl)-(3-hydroxyphenyl)methanone	IC50	100.0 [1]
	(5-Hydroxy-1-benzofuran-2-yl)-(3-hydroxyphenyl)methanone	IC50	1900.0 [1]
	(5-Hydroxy-1H-indol-2-yl)-(3-hydroxyphenyl)methanone	IC50	2000.0 [1]
	(5-Hydroxy-1-methylindol-2-yl)-(3-hydroxyphenyl)methanone	IC50	2100.0 [1]
	(5-Hydroxy-1-benzothiophen-2-yl)-(4-hydroxyphenyl)methanone	IC50	300.0 [1]
	(5-Hydroxy-1-benzofuran-2-yl)-(4-hydroxyphenyl)methanone	IC50	1000.0 [1]
	(5-Hydroxy-1-benzothiophen-2-yl)-(3-hydroxy-4-methylphenyl)methanone	IC50	50.0 [1]
	(2-Fluoro-5-hydroxyphenyl)-(5-hydroxy-1-benzothiophen-2-yl)methanone	IC50	50.0 [1]
	3-(5-Hydroxy-1-benzothiophene-2-carbonyl)benzonitrile	IC50	400.0 [1]
	(5-Hydroxy-1-benzothiophen-2-yl)-phenylmethanone	IC50	200.0 [1]
	(6-Hydroxynaphthalen-2-yl)-(3-hydroxyphenyl)methanone	IC50	1900.0 [1]
	12-[4-(Trifluoromethyl)phenyl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	1700.0 [1]
	12-(2,4-Difluorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	130.0 [1]
	12-(4-Chloro-2-fluorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	110.0 [1]
	12-(2-Chloro-4-fluorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	190.0 [1]
	12-(2-Fluoro-4-methoxyphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	71.0 [1]
	12-(4-Bromophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	910.0 [1]
	12-(4-Nitrophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	500.0 [1]
	12-(1,3-Benzodioxol-5-yl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	520.0 [1]
	12-Thiophen-2-yl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	180.0 [1]
	12-Pyrimidin-5-yl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	950.0 [1]
	11-(2,4-Dichlorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine	IC50	100.0 [1]
	Pyrido[3,4-G]quinazoline-2,10-Diamine	IC50	41.0 [1]
	Pyrido[3,4-G]quinazolin-2-Amine	IC50	190.0 [1]
	1-(5-Hydroxy-1-benzothiophen-2-yl)ethan-1-one	IC50	60.0 [1]
	(E)-2-(1H-Indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile	IC50	10000.0 [1]
	11H-Pyrido[3,4-a]carbazole-6-carbonitrile	IC50	170.0 [1]
	(3E)-3-[(4-Methoxyphenyl)methylidene]oxan-2-one	IC50	7520.0 [1]
	(5E)-2-Mercapto-5-(4-methoxybenzylidene)-1,3-thiazol-4(5H)-one	IC50	5700.0 [1]
	(3E)-3-(2,3-Dihydro-1-benzofuran-5-ylmethylidene)-5-methyloxolan-2-one	IC50	10000.0 [1]
	(3E)-3-(2,3-Dihydro-1,4-benzodioxin-6-ylmethylidene)oxolan-2-one	IC50	10000.0 [1]
	(3E)-3-(1,3-Benzothiazol-6-ylmethylidene)-5-methyloxolan-2-one	IC50	170.0 [1]
	(5Z)-5-(1,3-Benzothiazol-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	100.0 [1]
	(3E)-3-(3,4-Dihydro-2H-chromen-6-ylmethylidene)oxolan-2-one	IC50	3900.0 [1]
	(3E)-3-(1,3-Benzothiazol-6-ylmethylidene)oxolan-2-one	IC50	10000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Dual specificty protein kinase CLK1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/dual-specificty-protein-kinase-clk1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Dual specificty protein kinase CLK1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dual-specificty-protein-kinase-clk1-inhibitors-ic50-ki.
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