Endoplasmic reticulum aminopeptidase 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	[(2S)-2-[[(2S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamoyl]-4-methylpentyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	33.0 [1], 48.0 [2]
	[(2S)-2-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4,4-diphenylbutyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	3694.0 [1]
	[(2S)-2-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4,4-diphenylbutyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	Ki	3500.0 [1]
	Leucine Phosphonic Acid	Ki	5080.0 [1]
	Phosphonic acid, (1-amino-3-phenylpropyl)-	Ki	26900.0 [1]
	2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	19100.0 [1]
	2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-(4-hydroxyphenyl)propanoic acid	Ki	6470.0 [1]
	CID 118720630	Ki	530.0 [1]
	CID 127052870	Ki	250000.0 [1]
	[(1S)-1-Amino-3-methylbutyl]phosphonic acid	Ki	249000.0 [1]
	[1-Amino-2-(cyclohexylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	2-[[[1-Amino-3-(3,5-dimethylphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	31600.0 [1]
	2-[[[1-Amino-3-(3-hydroxyphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	87100.0 [1]
	2-[[[1-Amino-3-(4-hydroxyphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	11300.0 [1]
	2-[[[1-Amino-3-[4-(hydroxymethyl)phenyl]propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	991.0 [1]
	2-[[(1-Amino-3-pyridin-3-ylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	12300.0 [1]
	2-[[(1-Amino-3-pyridin-4-ylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	2540.0 [1]
	2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-(3,5-dimethylphenyl)propanoic acid	Ki	250000.0 [1]
	2-[[3-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-phenylpropyl)-hydroxyphosphoryl]propanoic acid	Ki	18600.0 [1]
	2-[[4-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-phenylpropyl)-hydroxyphosphoryl]propanoic acid	Ki	3730.0 [1]
	Methyl N-[4-Amino-3-(L-Arginylamino)benzene-1-Carbonyl]-L-Tyrosinate	IC50	9600.0 [1]
	(1-Amino-2-morpholin-4-ylethyl)phosphonic acid	Ki	250000.0 [1]
	2-[[[1-Amino-2-(2-methylpropylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	250000.0 [1]
	2-[[[1-Amino-2-(cyclohexylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	250000.0 [1]
	[1-Amino-2-(oxolan-2-ylmethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	(1-Amino-2-piperidin-1-ylethyl)phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-[(2-aminocyclohexyl)amino]ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(1-phenylethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-[2-(dimethylamino)ethylamino]ethyl]phosphonic acid	Ki	250000.0 [1]
	2-Benzyl-3-[1,2-diaminoethyl(hydroxy)phosphoryl]propanoic acid	Ki	250000.0 [1]
	[1-Amino-2-(cycloheptylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(2-phenylethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	2-[[[1-Amino-2-(propylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	250000.0 [1]
	[1-Amino-2-(2-piperazin-1-ylethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-[(4-tert-butylphenyl)methylamino]ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-[(4-aminophenyl)methylamino]ethyl]phosphonic acid	Ki	250000.0 [1]
	2-[[[1-Amino-2-(cycloheptylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	250000.0 [1]
	[1-Amino-2-[(4-methoxyphenyl)methylamino]ethyl]phosphonic acid	Ki	250000.0 [1]
	2-[[[1-Amino-2-[2-(4-methoxyphenyl)ethylamino]ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	250000.0 [1]
	[1-Amino-2-(hexylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-[[4-(aminomethyl)phenyl]methylamino]ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(piperidin-4-ylmethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(benzylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(methylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	(1,2-Diaminoethyl)phosphonic acid	Ki	250000.0 [1]
	(2s)-3-[(S)-[(1r)-1-Amino-3-Phenylpropyl](Hydroxy)phosphoryl]-2-Benzylpropanoic Acid	Ki	6270.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]hexanoate	IC50	2000.0 [1]
	CID 71817810	IC50	2600.0 [1]
	[(1r)-1-Amino-3-Phenylpropyl]phosphonic Acid	Ki	5550.0 [1]
	[1-Amino-2-(propylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(2-aminoethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoic acid	IC50	100000.0 [1]
	Methyl 4-amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoate	IC50	100000.0 [1]
	Methyl 4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoate	IC50	100000.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]hexanoate	IC50	100000.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]hexanoate	IC50	100000.0 [1]
	(2S)-6-Amino-2-[[4-amino-3-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoyl]amino]hexanoic acid	IC50	6800.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]hexanoate	IC50	18300.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]hexanoate	IC50	42000.0 [1]
	Methyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	110000.0 [1]
	Methyl (2S,3R)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-hydroxybutanoate	IC50	100000.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	9800.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	12100.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	100000.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	38400.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoate	IC50	100000.0 [1]
	Methyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	100000.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	920.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	3600.0 [1]
	Methyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-5-(diaminomethylideneamino)pentanoate	IC50	10700.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	1200.0 [1]
	Methyl 3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoate	IC50	100000.0 [1]
	Methyl (2S)-6-amino-2-[(3,4-diaminobenzoyl)amino]hexanoate	IC50	100000.0 [1]
	(2S)-2-[(3,4-Diaminobenzoyl)amino]-3-(1H-indol-3-yl)propanoic acid	IC50	100000.0 [1]
	Methyl (2S)-2-[(3,4-diaminobenzoyl)amino]-5-(diaminomethylideneamino)pentanoate	IC50	35000.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	9400.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	13400.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-5-(diaminomethylideneamino)pentanoate	IC50	12000.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	16700.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-phenylmethoxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	1100.0 [1]
	(2S)-2-[[3-Amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	19500.0 [1]
	Methyl (2S)-6-amino-2-[[3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]hexanoate	IC50	100000.0 [1]
	(2S)-2-[[3-Amino-4-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	800.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	8900.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoate	IC50	100000.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	100000.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	2500.0 [1]
	(2S)-2-[[3-Amino-4-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	2800.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	2600.0 [1]
	(2S)-2-[[3-Amino-4-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	38200.0 [1]
	[(1R)-1-Amino-3-phenylpropyl]-[(2S)-2-carbamoyl-4-methylpentyl]phosphinic acid	IC50	520.0 [1]
	2-[[4-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-pyridin-4-ylpropyl)-hydroxyphosphoryl]propanoic acid	Ki	1520.0 [1]
	2-[[3-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-pyridin-3-ylpropyl)-hydroxyphosphoryl]propanoic acid	Ki	4940.0 [1]
	[(2S)-2-[[(2S)-1-Amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]carbamoyl]-4-methylpentyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	1969.0 [1]
	[(2S)-3-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-oxo-2-[(3-phenyl-1,2-oxazol-5-yl)methyl]propyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	126.0 [1]
	[(2S)-3-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]amino]-2-[[3,5-bis(3-chlorophenyl)phenyl]methyl]-3-oxopropyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	25111.0 [1]
	[(2S)-2-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]carbamoyl]-4,4-diphenylbutyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	31212.0 [1]
	[(2S)-2-[[(2S)-1-Amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]-4-methylpentyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	7473.0 [1]
	[(2R)-3-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-2-[(3,5-diphenylphenyl)methyl]-3-oxopropyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	100000.0 [1]
	[(2S)-2-(1-Adamantylmethyl)-3-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-oxopropyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	726.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Endoplasmic reticulum aminopeptidase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/endoplasmic-reticulum-aminopeptidase-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Endoplasmic reticulum aminopeptidase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/endoplasmic-reticulum-aminopeptidase-1-inhibitors-ic50-ki.
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