Endoplasmic reticulum aminopeptidase 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	[(2S)-2-[[(2S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamoyl]-4-methylpentyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	11.0 [1], 50.0 [2], 80.0 [3]
	Methyl N-[4-Amino-3-(L-Arginylamino)benzene-1-Carbonyl]-L-Tyrosinate	IC50	518.0 [1], 2000.0 [2]
	[(2S)-2-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4,4-diphenylbutyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	IC50	740.0 [1]
	[(2S)-2-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4,4-diphenylbutyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acid	Ki	200.0 [1]
	Leucine Phosphonic Acid	Ki	250000.0 [1]
	Phosphonic acid, (1-amino-3-phenylpropyl)-	Ki	250000.0 [1]
	2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	350.0 [1]
	2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-(4-hydroxyphenyl)propanoic acid	Ki	1040.0 [1]
	CID 118720630	Ki	152.0 [1]
	CID 127052870	Ki	1680.0 [1]
	[(1S)-1-Amino-3-methylbutyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(cyclohexylamino)ethyl]phosphonic acid	Ki	8190.0 [1]
	2-[[[1-Amino-3-(3,5-dimethylphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	7670.0 [1]
	2-[[[1-Amino-3-(3-hydroxyphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	4570.0 [1]
	2-[[[1-Amino-3-(4-hydroxyphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	2180.0 [1]
	2-[[[1-Amino-3-[4-(hydroxymethyl)phenyl]propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	185.0 [1]
	2-[[(1-Amino-3-pyridin-3-ylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	205.0 [1]
	2-[[(1-Amino-3-pyridin-4-ylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	241.0 [1]
	2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-(3,5-dimethylphenyl)propanoic acid	Ki	250000.0 [1]
	2-[[3-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-phenylpropyl)-hydroxyphosphoryl]propanoic acid	Ki	250000.0 [1]
	2-[[4-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-phenylpropyl)-hydroxyphosphoryl]propanoic acid	Ki	250000.0 [1]
	(1-Amino-2-morpholin-4-ylethyl)phosphonic acid	Ki	250000.0 [1]
	2-[[[1-Amino-2-(2-methylpropylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	55300.0 [1]
	2-[[[1-Amino-2-(cyclohexylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	7940.0 [1]
	[1-Amino-2-(oxolan-2-ylmethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	(1-Amino-2-piperidin-1-ylethyl)phosphonic acid	Ki	622.0 [1]
	[1-Amino-2-[(2-aminocyclohexyl)amino]ethyl]phosphonic acid	Ki	10300.0 [1]
	[1-Amino-2-(1-phenylethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-[2-(dimethylamino)ethylamino]ethyl]phosphonic acid	Ki	250000.0 [1]
	2-Benzyl-3-[1,2-diaminoethyl(hydroxy)phosphoryl]propanoic acid	Ki	3020.0 [1]
	[1-Amino-2-(cycloheptylamino)ethyl]phosphonic acid	Ki	10600.0 [1]
	[1-Amino-2-(2-phenylethylamino)ethyl]phosphonic acid	Ki	1020.0 [1]
	2-[[[1-Amino-2-(propylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	5540.0 [1]
	[1-Amino-2-(2-piperazin-1-ylethylamino)ethyl]phosphonic acid	Ki	7700.0 [1]
	[1-Amino-2-[(4-tert-butylphenyl)methylamino]ethyl]phosphonic acid	Ki	11500.0 [1]
	[1-Amino-2-[(4-aminophenyl)methylamino]ethyl]phosphonic acid	Ki	24900.0 [1]
	2-[[[1-Amino-2-(cycloheptylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	9510.0 [1]
	[1-Amino-2-[(4-methoxyphenyl)methylamino]ethyl]phosphonic acid	Ki	8230.0 [1]
	2-[[[1-Amino-2-[2-(4-methoxyphenyl)ethylamino]ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid	Ki	1300.0 [1]
	[1-Amino-2-(hexylamino)ethyl]phosphonic acid	Ki	632.0 [1]
	[1-Amino-2-[[4-(aminomethyl)phenyl]methylamino]ethyl]phosphonic acid	Ki	3470.0 [1]
	[1-Amino-2-(piperidin-4-ylmethylamino)ethyl]phosphonic acid	Ki	1420.0 [1]
	[1-Amino-2-(benzylamino)ethyl]phosphonic acid	Ki	106000.0 [1]
	[1-Amino-2-(methylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	(1,2-Diaminoethyl)phosphonic acid	Ki	16900.0 [1]
	(2s)-3-[(S)-[(1r)-1-Amino-3-Phenylpropyl](Hydroxy)phosphoryl]-2-Benzylpropanoic Acid	Ki	1030.0 [1]
	N-Benzyl-2-[(4-fluorophenyl)methyl]-N'-hydroxypropanediamide	IC50	100000.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]hexanoate	IC50	24900.0 [1]
	CID 71817810	IC50	8900.0 [1]
	[(1r)-1-Amino-3-Phenylpropyl]phosphonic Acid	Ki	47000.0 [1]
	[1-Amino-2-(propylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	[1-Amino-2-(2-aminoethylamino)ethyl]phosphonic acid	Ki	250000.0 [1]
	Methyl 3-amino-4-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoate	IC50	100000.0 [1]
	Methyl 4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoate	IC50	100000.0 [1]
	4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoic acid	IC50	3200.0 [1]
	Methyl 4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoate	IC50	9800.0 [1]
	Methyl 4-amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoate	IC50	3700.0 [1]
	4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoic acid	IC50	100000.0 [1]
	(2S)-6-Amino-2-[[4-amino-3-[[(2S)-2-amino-3-phenylpropanoyl]amino]benzoyl]amino]hexanoic acid	IC50	2600.0 [1]
	(2S)-6-Amino-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]hexanoic acid	IC50	4500.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]hexanoate	IC50	4800.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]hexanoate	IC50	13000.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoyl]amino]hexanoate	IC50	52000.0 [1]
	(2S)-6-Amino-2-[[4-amino-3-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoyl]amino]hexanoic acid	IC50	2100.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]hexanoate	IC50	8300.0 [1]
	Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]hexanoate	IC50	17000.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-methylbutanoate	IC50	50000.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-methylbutanoic acid	IC50	100000.0 [1]
	Methyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	33000.0 [1]
	Methyl (2S,3R)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-hydroxybutanoate	IC50	39000.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	40000.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	100000.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	100000.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	100000.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoate	IC50	100000.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoic acid	IC50	100000.0 [1]
	Methyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	6400.0 [1]
	Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	1600.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	3800.0 [1]
	Methyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-5-(diaminomethylideneamino)pentanoate	IC50	2500.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]-3-methylbutanoic acid	IC50	5000.0 [1]
	(2S)-2-[[4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	589.0 [1]
	Methyl 3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoate	IC50	58000.0 [1]
	Methyl 3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoate	IC50	58000.0 [1]
	Methyl 3-amino-4-[[(2S)-2-aminohexanoyl]amino]benzoate	IC50	1100.0 [1]
	Methyl 3-amino-4-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoate	IC50	2500.0 [1]
	Benzyl (2S)-2-[(3,4-diaminobenzoyl)amino]-3-(1H-indol-3-yl)propanoate	IC50	100000.0 [1]
	(2S)-2-[(3,4-Diaminobenzoyl)amino]-3-(1H-indol-3-yl)propanoic acid	IC50	1900.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-methylbutanoate	IC50	100000.0 [1]
	(2S)-2-[[3-Amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-methylbutanoic acid	IC50	100000.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	5500.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	11000.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-5-(diaminomethylideneamino)pentanoate	IC50	11800.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-phenylmethoxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	16000.0 [1]
	Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoate	IC50	15100.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-phenylmethoxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	20500.0 [1]
	(2S)-2-[[3-Amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	4800.0 [1]
	Methyl (2S)-6-amino-2-[[3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]hexanoate	IC50	100000.0 [1]
	Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoate	IC50	70000.0 [1]
	(2S)-2-[[3-Amino-4-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acid	IC50	9400.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Endoplasmic reticulum aminopeptidase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/endoplasmic-reticulum-aminopeptidase-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Endoplasmic reticulum aminopeptidase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/endoplasmic-reticulum-aminopeptidase-2-inhibitors-ic50-ki.
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