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Endothelin receptor ET-A Inhibitors (IC50, Ki)
Structure
Compound Name
Standard Type
Standard Values (in nM)
EndothelinIC500.05 [1], 0.2 [2], 0.38 [3]
EndothelinKi0.14 [1]
BosentanIC5040.0 [1]
BosentanKi6.5 [1], 8.0 [2]
5-(Dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamideIC505.8 [1], 50.12 [2], 150.0 [3], 570.0 [4]

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References
This online resource may be cited as follows
MLA
"Quest Database™ Endothelin receptor ET-A Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 15 May. 2026, https://www.aatbio.com/data-sets/endothelin-receptor-et-a-inhibitors-ic50-ki.
APA
AAT Bioquest, Inc. (2026, May 15). Quest Database™ Endothelin receptor ET-A Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/endothelin-receptor-et-a-inhibitors-ic50-ki.
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