 | Xct790 | IC50 | 270.0 [1], 370.0 [2] |
 | 4-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile | IC50 | 40.0 [1], 600.0 [2] |
 | Estradiol | IC50 | 3.6 [1], 6.0 [2] |
 | 1-Cyclohexyl-N-{[1-(4-Methylphenyl)-1h-Indol-3-Yl]methyl}methanamine | IC50 | 190.0 [1] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-nitrobenzoic Acid Methyl Ester | IC50 | 470.0 [1], 10000.0 [2] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-2-trifluoromethylbenzonitrile | IC50 | 470.0 [1], 10000.0 [2] |
 | Methyl 4-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]-2-(trifluoromethyl)benzoate | IC50 | 57.0 [1], 10000.0 [2] |
 | Methyl 4-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]-3-(trifluoromethyl)benzoate | IC50 | 16.0 [1], 1500.0 [2] |
 | Methyl 2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]-5-(trifluoromethyl)benzoate | IC50 | 70.0 [1], 9300.0 [2] |
 | 2-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-5-trifluoromethylbenzonitrile | IC50 | 240.0 [1], 4500.0 [2] |
 | 5-[4-(2-Chloro-4-trifluoromethylphenoxy)-3-methoxybenzylidene]thiazolidine-2,4-dione | IC50 | 165.0 [1], 2300.0 [2] |
 | Methyl 4-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]naphthalene-1-carboxylate | IC50 | 13.0 [1], 90.0 [2] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-naphthalene-1-carbonitrile | IC50 | 62.0 [1], 2300.0 [2] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-bromobenzonitrile | IC50 | 720.0 [1], 6300.0 [2] |
 | 5-[4-(2-Bromo-4-trifluoromethylphenoxy)-3-methoxybenzylidene]thiazolidine-2,4-dione | IC50 | 140.0 [1], 2700.0 [2] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-chlorobenzonitrile | IC50 | 540.0 [1], 10000.0 [2] |
 | (6Z)-6-[[4-[2-(2,6-Dimethylphenoxy)ethoxy]-3-methoxyphenyl]methylidene]-2-ethyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | IC50 | 1400.0 [1], 2300.0 [2] |
 | 5-[3-Methoxy-4-(2-nitro-4-trifluoromethylphenoxy)benzylidene]-thiazolidine-2,4-dione | IC50 | 270.0 [1], 3600.0 [2] |
 | 5-[3-Methoxy-4-(2-nitrophenoxy)benzylidene]thiazolidine-2,4-dione | IC50 | 290.0 [1], 10000.0 [2] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-nitrobenzonitrile | IC50 | 1100.0 [1], 10000.0 [2] |
 | 5-[3-Methoxy-4-(4-nitro-3-trifluoromethylphenoxy)benzylidene]-thiazolidine-2,4-dione | IC50 | 280.0 [1], 5000.0 [2] |
 | Methyl 3-chloro-4-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]benzoate | IC50 | 47.0 [1], 5900.0 [2] |
 | Methyl 3-bromo-4-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methoxyphenoxy]benzoate | IC50 | 80.0 [1], 3400.0 [2] |
 | (5Z)-5-[[4-[2,4-Bis(trifluoromethyl)phenoxy]-3-methoxyphenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 36.0 [1], 10000.0 [2] |
 | 5-[4-(2-Trifluoromethylphenoxy)-3-methoxybenzylidene]-thiazolidine-2,4-dione | IC50 | 68.0 [1], 700.0 [2] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-2-methylbenzonitrile | IC50 | 890.0 [1], 10000.0 [2] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-phthalonitrile | IC50 | 220.0 [1], 6900.0 [2] |
 | Tamoxifen | IC50 | 200.0 [1] |
 | Genistein | IC50 | 10.0 [1] |
 | Kaempferol | IC50 | 9640.0 [1] |
 | Fulvestrant | IC50 | 2.0 [1] |
 | 4-[(1S,7S,7Ar)-1-ethyl-7-hydroxy-3-oxo-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile | Ki | 10000.0 [1] |
 | 1-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methyl]-3-phenylurea | IC50 | 21080.0 [1] |
 | 2-(4-Hydroxyphenyl)-4-vinylquinolin-6-ol | IC50 | 60.0 [1] |
 | 4-Cyano-2-(4-hydroxyphenyl)quinolin-6-ol | IC50 | 28.0 [1] |
 | 4-Ethyl-2-(4-hydroxyphenyl)quinolin-6-ol | IC50 | 52.0 [1] |
 | 4-Bromo-2-(4-hydroxyphenyl)quinolin-6-ol | IC50 | 4.3 [1] |
 | 4-Chloro-2-(4-hydroxyphenyl)quinolin-6-ol | IC50 | 4.6 [1] |
 | 4-Ethynyl-2-(4-hydroxyphenyl)quinolin-6-ol | IC50 | 75.0 [1] |
 | Methyl 2-butoxy-5-[[2,5-diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]benzoate | IC50 | 3430.0 [1] |
 | 5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-phenylbenzamide | IC50 | 3720.0 [1] |
 | 5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-(4-methylphenyl)benzamide | IC50 | 3040.0 [1] |
 | 5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-(3-methoxyphenyl)benzamide | IC50 | 4230.0 [1] |
 | (E)-3-[4-[[2,4-Bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide | IC50 | 750.0 [1] |
 | (E)-2-Cyano-3-[4-[2-(2,6-dimethylphenoxy)ethoxy]-3-methoxyphenyl]-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide | IC50 | 1400.0 [1] |
 | (E)-2-Cyano-3-[4-[2-(2,6-dimethylphenoxy)ethoxy]-3-methoxyphenyl]-N-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)prop-2-enamide | IC50 | 2600.0 [1] |
 | (E)-N-(5-Tert-butyl-1,3,4-thiadiazol-2-yl)-2-cyano-3-[4-[2-(2,6-dimethylphenoxy)ethoxy]-3-methoxyphenyl]prop-2-enamide | IC50 | 1700.0 [1] |
 | (E)-2-Cyano-3-[4-[2-(2,6-dimethylphenoxy)ethoxy]-3-methoxyphenyl]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide | IC50 | 1500.0 [1] |
 | (E)-2-Cyano-N-[5-[4-(dimethylamino)phenyl]-1,3,4-thiadiazol-2-yl]-3-[4-[2-(2,6-dimethylphenoxy)ethoxy]-3-methoxyphenyl]prop-2-enamide | IC50 | 2000.0 [1] |
 | (E)-2-Cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-[4-[[4-fluoro-2-(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]prop-2-enamide | IC50 | 1500.0 [1] |
 | (E)-2-Cyano-3-[4-[2-(2,6-dimethylphenoxy)ethoxy]-3-methoxyphenyl]-N-(5-ethyl-1,3,4-oxadiazol-2-yl)prop-2-enamide | IC50 | 3300.0 [1] |
 | (E)-2-Cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-[3-methoxy-4-[[2-(trifluoromethoxy)phenyl]methoxy]phenyl]prop-2-enamide | IC50 | 1800.0 [1] |
 | (E)-3-[4-[(2-Bromophenyl)methoxy]-3-methoxyphenyl]-2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)prop-2-enamide | IC50 | 2200.0 [1] |
 | (E)-3-[4-[[2,4-Bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-(5-phenyl-1,3,4-thiadiazol-2-yl)prop-2-enamide | IC50 | 500.0 [1] |
 | (E)-2-Cyano-3-[4-[2-(2,6-dimethylphenoxy)ethoxy]-3-methoxyphenyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)prop-2-enamide | IC50 | 2000.0 [1] |
 | (E)-3-[4-[[2,4-Bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-2-cyanoprop-2-enamide | IC50 | 10000.0 [1] |
 | (E)-2-Cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-[3-methoxy-4-(naphthalen-1-ylmethoxy)phenyl]prop-2-enamide | IC50 | 1800.0 [1] |
 | (E)-2-Cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-[4-[[5-fluoro-2-(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]prop-2-enamide | IC50 | 1700.0 [1] |
 | (E)-3-[4-[[2,4-Bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)prop-2-enamide | IC50 | 540.0 [1] |
 | 4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenol;hydrochloride | IC50 | 10000.0 [1] |
 | 7-(3-Chlorophenyl)-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 144.0 [1] |
 | 3-(3,9-Dihydroxy-6H-chromeno[4,3-b]quinolin-7-yl)benzonitrile | IC50 | 150.0 [1] |
 | 4-(3,9-Dihydroxy-6H-chromeno[4,3-b]quinolin-7-yl)benzonitrile | IC50 | 65.0 [1] |
 | 7-Vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 22.0 [1] |
 | 7-(3-Methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 86.0 [1] |
 | 3,9-DIHYDROXY-7-[4-(TRIFLUOROMETHYL)PHENYL]-6H-CHROMENO[4,3-b]QUINOLINE | IC50 | 319.0 [1] |
 | 7-Ethynyl-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 52.0 [1] |
 | 7-(4-Chlorophenyl)-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 160.0 [1] |
 | 7-Ethyl-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 46.0 [1] |
 | 7-Chloro-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 3.3 [1] |
 | 7-(4-Methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 94.0 [1] |
 | 3,9-Dihydroxy-6H-chromeno[4,3-b]quinoline-7-carbonitrile | IC50 | 6.1 [1] |
 | 7-Bromo-6H-chromeno[4,3-b]quinoline-3,9-diol | IC50 | 3.6 [1] |
 | N-[5-[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]pentyl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propanamide | IC50 | 80.0 [1] |
 | N-[[4-[[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]methyl]phenyl]methyl]-3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)propanamide | IC50 | 170.0 [1] |
 | 1-[3-[[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]methyl]pyrrolidin-1-yl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propan-1-one | IC50 | 770.0 [1] |
 | 1-[4-[[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]methyl]piperidin-1-yl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propan-1-one | IC50 | 210.0 [1] |
 | N-[2-[2-[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]ethoxy]ethyl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propanamide | IC50 | 280.0 [1] |
 | N-[3-[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]propyl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propanamide | IC50 | 490.0 [1] |
 | N-[2-[2-[2-[2-[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propanamide | IC50 | 570.0 [1] |
 | N-[4-[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]butyl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propanamide | IC50 | 170.0 [1] |
 | 1-[6-[(2R)-4-[1-[[3-(2-Methoxyethoxy)phenyl]methyl]-3-methylthieno[2,3-c]pyrazole-5-carbonyl]-2-methylpiperazin-1-yl]pyridin-3-yl]ethanone | IC50 | 22.0 [1] |
 | N-[2-[2-[2-[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]ethoxy]ethoxy]ethyl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propanamide | IC50 | 390.0 [1] |
 | N-[2-[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]ethyl]-3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)propanamide | IC50 | 650.0 [1] |
 | 1-[2-[[3-[[5-[(3R)-4-(5-Acetylpyridin-2-yl)-3-methylpiperazine-1-carbonyl]-3-methylthieno[2,3-c]pyrazol-1-yl]methyl]phenoxy]methyl]morpholin-4-yl]-3-(2,2-difluoro-10,12-dimethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)propan-1-one | IC50 | 1000.0 [1] |
 | N-Benzyl-5-[[2,5-diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxybenzamide | IC50 | 3810.0 [1] |
 | Methyl 5-[[2,5-diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-phenylmethoxybenzoate | IC50 | 4060.0 [1] |
 | 5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-[(4-methoxyphenyl)methyl]benzamide | IC50 | 1900.0 [1] |
 | 5-[[2,5-Diethoxy-4-(methanesulfonamido)phenyl]methylcarbamoylamino]-2-ethoxy-N-propan-2-ylbenzamide | IC50 | 3480.0 [1] |
 | (5Z)-5-[[1-[[4-Chloro-2-(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-3-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-1,3-thiazolidine-2,4-dione | IC50 | 45.0 [1] |
 | (Cyclohexylmethyl)[(1-phenyl-1H-indol-3-yl)methyl]amine | IC50 | 700.0 [1] |
 | 6-(3,5-Dimethyl-1,2-oxazol-4-yl)-2,2,4,4-tetramethyl-1,7,8,9-tetrahydrocyclopenta[h]quinolin-3-one | Ki | 2300.0 [1] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)phenoxy]-2-trifluoromethylbenzonitrile | IC50 | 720.0 [1] |
 | 4-[4-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-methylphenoxy]-2-(trifluoromethyl)benzonitrile | IC50 | 800.0 [1] |
 | 4-[4-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-ethoxyphenoxy]-2-(trifluoromethyl)benzonitrile | IC50 | 350.0 [1] |
 | 4-[4-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-3-methoxyphenoxy]-2-(trifluoromethyl)benzonitrile | IC50 | 730.0 [1] |
 | 4-[4-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,6-dimethoxyphenoxy]-2-(trifluoromethyl)benzonitrile | IC50 | 1800.0 [1] |
 | 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)naphthalen-1-yloxy]-2-trifluoromethylbenzonitrile | IC50 | 2600.0 [1] |
 | 2-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-5-nitrobenzonitrile | IC50 | 1000.0 [1] |
 | 2-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-benzonitrile | IC50 | 2400.0 [1] |
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