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Estrogen-related receptor beta Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
EstradiolIC503.2 [1], 8.7 [2]
(Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)-phenyl)-2-phenylbut-1-en-1-yl)phenolIC50650.0 [1], 886.0 [2]
GenisteinIC50395.0 [1]
(Z)-4-(1-{4-[2-(Dimethylamino)ethoxy]phenyl}-5-hydroxy-2-phenylpent-1-enyl)phenolIC503500.0 [1]
4-[(1S,7S,7Ar)-1-ethyl-7-hydroxy-3-oxo-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrileKi10000.0 [1]
2-(4-Hydroxyphenyl)-4-vinylquinolin-6-olIC50504.0 [1]
4-Cyano-2-(4-hydroxyphenyl)quinolin-6-olIC50455.0 [1]
4-Ethyl-2-(4-hydroxyphenyl)quinolin-6-olIC50634.0 [1]
4-Bromo-2-(4-hydroxyphenyl)quinolin-6-olIC50212.0 [1]
4-Chloro-2-(4-hydroxyphenyl)quinolin-6-olIC50213.0 [1]
4-Ethynyl-2-(4-hydroxyphenyl)quinolin-6-olIC501500.0 [1]
[4-[(E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-3-methyl-2-phenylbut-1-enyl]phenyl] acetateIC5010.0 [1]
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-3-methyl-2-phenylbut-1-enyl]phenolIC50210.0 [1]
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-4-methyl-2-phenylpent-1-enyl]phenolIC50750.0 [1]
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenol;hydrochlorideIC5010000.0 [1]
Methyl (Z)-5-[4-[2-(dimethylamino)ethoxy]phenyl]-5-(4-hydroxyphenyl)-4-phenylpent-4-enoateIC50350.0 [1]
Methyl (Z)-5-[4-[2-(dimethylamino)ethoxy]phenyl]-5-(4-hydroxyphenyl)-2-methyl-4-phenylpent-4-enoateIC5050.0 [1]
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-hydroxy-4-methyl-2-phenylpent-1-enyl]phenolIC502250.0 [1]
7-(3-Chlorophenyl)-6H-chromeno[4,3-b]quinoline-3,9-diolIC50504.0 [1]
3-(3,9-Dihydroxy-6H-chromeno[4,3-b]quinolin-7-yl)benzonitrileIC501130.0 [1]
4-(3,9-Dihydroxy-6H-chromeno[4,3-b]quinolin-7-yl)benzonitrileIC501017.0 [1]
7-Vinyl-6H-chromeno[4,3-b]quinoline-3,9-diolIC50526.0 [1]
7-(3-Methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,9-diolIC50820.0 [1]
3,9-DIHYDROXY-7-[4-(TRIFLUOROMETHYL)PHENYL]-6H-CHROMENO[4,3-b]QUINOLINEIC505235.0 [1]
7-Ethynyl-6H-chromeno[4,3-b]quinoline-3,9-diolIC50624.0 [1]
7-(4-Chlorophenyl)-6H-chromeno[4,3-b]quinoline-3,9-diolIC502345.0 [1]
7-Ethyl-6H-chromeno[4,3-b]quinoline-3,9-diolIC50641.0 [1]
7-Chloro-6H-chromeno[4,3-b]quinoline-3,9-diolIC5088.0 [1]
7-(4-Methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,9-diolIC50549.0 [1]
3,9-Dihydroxy-6H-chromeno[4,3-b]quinoline-7-carbonitrileIC5098.0 [1]
7-Bromo-6H-chromeno[4,3-b]quinoline-3,9-diolIC5056.0 [1]
Methyl 5,5-bis(4-hydroxyphenyl)-4-phenylpent-4-enoateIC50600.0 [1]
[4-[(E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-hydroxy-4-methyl-2-phenylpent-1-enyl]phenyl] acetateIC50550.0 [1]
[4-[(E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenyl] acetateIC501100.0 [1]
Methyl 5,5-bis(4-hydroxyphenyl)-2-methyl-4-phenylpent-4-enoateIC50300.0 [1]
Chembl4174856IC5010000.0 [1]
Tert-butyl 4-[4-[6-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]hex-1-ynyl]phenyl]piperazine-1-carboxylateIC50436.4 [1]
(7R,8R,9S,13S,14S,17S)-13-Methyl-7-[6-[4-(1,2-oxazol-5-yl)phenyl]hex-5-ynyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diolIC50331.1 [1]
Ethyl 3-[4-[6-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]hex-1-ynyl]phenyl]-3-oxopropanoateIC50185.0 [1]
Diethyl 2-[[4-[6-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]hex-1-ynyl]phenyl]methyl]propanedioateIC50150.6 [1]
(7R,8R,9S,13S,14S,17S)-13-Methyl-7-[6-(4-pyrrol-1-ylphenyl)hex-5-ynyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diolIC5019.1 [1]
(7R,8R,9S,13S,14S,17S)-13-Methyl-7-[6-[4-(piperidin-1-ylmethyl)phenyl]hex-5-ynyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diolIC50565.9 [1]
(7R,8R,9S,13S,14S,17S)-13-Methyl-7-(6-naphthalen-2-ylhex-5-ynyl)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diolIC50120.7 [1]
3-[4-[4-[(7R,8R,9S,13S,14S,17S)-3,17-Dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]butyl]triazol-1-yl]-7-hydroxychromen-2-oneIC50111.9 [1]
(7R,8R,9S,13S,14S,17S)-7-[4-[1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)triazol-4-yl]butyl]-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diolIC5041.2 [1]
4-[(Z)-1-[4-[3-(Dimethylamino)propoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenolIC5010000.0 [1]
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5,5-difluoro-2-phenylpent-1-enyl]phenolIC5010000.0 [1]
4-[(Z)-5-Hydroxy-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylpent-1-enyl]phenolIC5010000.0 [1]
(E)-5-(4-Bromophenyl)-5-[4-[2-(dimethylamino)ethoxy]phenyl]-4-phenylpent-4-en-1-olIC506950.0 [1]
(Z)-5-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-methylphenyl)-4-phenylpent-4-en-1-olIC5010000.0 [1]
4-[(Z)-1-[4-[2-(Diethylamino)ethoxy]phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenolIC5010000.0 [1]
4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-fluoro-2-phenylpent-1-enyl]phenolIC50722.0 [1]
Items per page: 1 - 10 of 52
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References

This online tool may be cited as follows

MLA

"Quest Database™ Estrogen-related receptor beta Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/estrogen-related-receptor-beta-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Estrogen-related receptor beta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/estrogen-related-receptor-beta-inhibitors-ic50-ki.
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