Eukaryotic translation initiation factor 2-alpha kinase 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 53469448	IC50	420.0 [1]
	CID 53469059	IC50	460.0 [1]
	Ripk1-IN-7	IC50	26.0 [1]
	5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamide	IC50	10000.0 [1]
	3-[(2,6-Dichlorophenyl)methylamino]-6,7-dimethoxy-1H-indeno[1,2-c]pyrazol-4-one	IC50	6.31 [1]
	N-[5-(6,7-Dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1-methyl-3-oxo-2,5-diphenylpyrazole-4-carboxamide	IC50	10000.0 [1]
	N-[(2-Chlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	199.53 [1]
	3-[[3-[(2,6-Dichlorophenyl)methylamino]-7-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-6-yl]oxy]propane-1,2-diol	IC50	31.62 [1]
	6,7-Dimethoxy-N-[(2-methoxyphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	3162.28 [1]
	6,7-Dimethoxy-N-[(2-methylphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	63.1 [1]
	N-Benzyl-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	630.96 [1]
	N-[(2,6-Dichlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	2511.89 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-5,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	125.89 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-7-ethyl-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	316.23 [1]
	3-N-[(2-Chloro-6-methylphenyl)methyl]-7-N,7-N-dimethyl-1,4-dihydroindeno[1,2-c]pyrazole-3,7-diamine	IC50	251.19 [1]
	7-Bromo-N-[(2-chloro-6-methylphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	794.33 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-7-methylsulfanyl-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	1000.0 [1]
	N-[(3-Chlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	1000.0 [1]
	N-[(4-Chlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	2511.89 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	1584.89 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-8-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	10000.0 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-7-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	50.12 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-6-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	501.19 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-5-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	794.33 [1]
	N-[(2,4-Dichlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	1258.93 [1]
	N-[(2,6-Dimethylphenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	7.94 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amine	IC50	19.95 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-4,6-dioxa-11,12-diazatetracyclo[7.6.0.03,7.010,14]pentadeca-1,3(7),8,10(14),12-pentaen-13-amine	IC50	251.19 [1]
	N-[(2,6-Dichlorophenyl)methyl]-6,7-dimethoxy-1H-[1]benzofuro[3,2-c]pyrazol-3-amine	IC50	63.1 [1]
	N-[(2-Chloro-6-methylphenyl)methyl]-6,7-dimethoxy-1H-[1]benzothiolo[3,2-c]pyrazol-3-amine	IC50	501.19 [1]
	N-[(2,6-Dichlorophenyl)methyl]-6,7-dimethoxy-4,4-dioxo-1H-[1]benzothiolo[3,2-c]pyrazol-3-amine	IC50	79.43 [1]
	N-[(2,6-Dichlorophenyl)methyl]-7,8-dimethoxy-4,5-dihydro-1H-benzo[g]indazol-3-amine	IC50	10000.0 [1]
	N-[(2,6-Dichlorophenyl)methyl]-12,13-dimethoxy-3,4-diazatricyclo[8.4.0.02,6]tetradeca-1(14),2(6),4,10,12-pentaen-5-amine	IC50	10000.0 [1]
	1-[5-(4-Aminothieno[3,2-C]pyridin-3-Yl)-2,3-Dihydro-1h-Indol-1-Yl]-2-Phenylethanone	IC50	17020.0 [1]
	1-[5-[4-Amino-7-(1-methylpyrazol-4-yl)thieno[3,2-c]pyridin-3-yl]-2,3-dihydroindol-1-yl]-2-phenylethanone	IC50	1863.0 [1]
	1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-[6-(trifluoromethyl)pyridin-2-yl]ethanone	IC50	37.0 [1]
	1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(3,5-dimethylpyrazol-1-yl)ethanone	IC50	61.0 [1]
	5-{1-[(3-Chlorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine	IC50	214.0 [1]
	3-[1-(Phenylacetyl)-2,3-dihydro-1H-indol-5-yl]-7-(3-pyridinyl)thieno[3,2-c]pyridin-4-amine	IC50	12080.0 [1]
	2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)phenyl]-4-Methyl-3-[2-(Methylamino)quinazolin-6-Yl]benzamide	IC50	10000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 40 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Eukaryotic translation initiation factor 2-alpha kinase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/eukaryotic-translation-initiation-factor-2-alpha-kinase-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Eukaryotic translation initiation factor 2-alpha kinase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/eukaryotic-translation-initiation-factor-2-alpha-kinase-1-inhibitors-ic50-ki.
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