Fibroblast growth factor receptor 3 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Infigratinib phosphate	IC50	4.9 [1]
	Azd4547	IC50	5.5 [1]
	4-N-(3,5-Dimethoxyphenyl)-4-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-1-N-propan-2-ylcyclohexane-1,4-diamine	IC50	13.49 [1]
	Staurosporine	IC50	9.25 [1], 10.3 [2], 14.71 [3], 15.6 [4], 18.0 [5]
	1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]pyrrolidin-3-ol;hydrochloride	IC50	1.82 [1], 2.51 [2], 3.02 [3], 26.92 [4], 10000.0 [5]
	1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-3-ol;hydrochloride	IC50	0.58 [1], 0.65 [2], 1.7 [3], 16.22 [4], 10000.0 [5]
	N'-(2,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine	IC50	151.36 [1], 204.17 [2], 2570.4 [3], 10000.0 [4]
	3-[1-(2-Aminoethyl)pyrazol-4-yl]-N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine	IC50	5.01 [1], 6.76 [2], 181.97 [3], 2089.3 [4], 5888.44 [5]
	2-(2-Chloro-5-methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethanol	IC50	3.63 [1], 6.46 [2], 12.02 [3], 891.25 [4], 10000.0 [5]
	[(2R)-1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]pyrrolidin-2-yl]methanol	IC50	1.1 [1], 1.82 [2], 2.82 [3], 93.33 [4], 10000.0 [5]
	N-(3,5-Dimethoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-pyrrolidin-1-ylpropyl)quinoxalin-6-amine	IC50	0.51 [1], 1.1 [2], 2.09 [3], 16.98 [4], 9772.37 [5]
	N-[3-(3-Aminopyrrolidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine	IC50	1.41 [1], 1.66 [2], 8.71 [3], 74.13 [4], 7762.47 [5]
	1-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-(propan-2-ylamino)propan-2-ol	IC50	0.89 [1], 1.29 [2], 2.63 [3], 165.96 [4], 10000.0 [5]
	N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-[3-(3-piperidin-1-ylpyrrolidin-1-yl)propyl]quinoxalin-6-amine	IC50	1.35 [1], 3.8 [2], 6.31 [3], 229.09 [4], 6760.83 [5]
	[(2S)-1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]pyrrolidin-2-yl]methanol	IC50	0.91 [1], 1.0 [2], 2.34 [3], 23.99 [4], 10000.0 [5]
	2-[4-[7-[N-(2-Aminoethyl)-3,5-dimethoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanol;hydrochloride	IC50	1.51 [1], 2.69 [2], 134.9 [3], 10000.0 [4]
	1-(3,3-Difluoropyrrolidin-1-yl)-3-(3,5-dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propan-2-ol;hydrochloride	IC50	2.4 [1], 6.17 [2], 109.65 [3], 10000.0 [4]
	2-(2,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethanol;hydrochloride	IC50	83.18 [1], 100.0 [2], 1621.81 [3], 10000.0 [4]
	N-(3,5-Dimethoxyphenyl)-N-[2-[(3R,5R)-3,5-dimethylpiperidin-1-yl]ethyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	6.17 [1], 21.88 [2], 338.84 [3], 10000.0 [4]
	2-[3-[Cyclopropylmethyl-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]amino]-5-methoxyphenoxy]ethanol	IC50	3.02 [1], 37.15 [2], 1380.38 [3], 10000.0 [4]
	N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-[2-(methylamino)ethyl]pyrazol-4-yl]quinoxalin-6-amine	IC50	5.13 [1], 346.74 [2], 2137.96 [3], 5248.07 [4]
	N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,6,6-tetramethylpiperidin-4-yl)ethane-1,2-diamine	IC50	26.92 [1], 120.23 [2], 1621.81 [3], 7762.47 [4]
	[(2R)-1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-2-yl]methanol	IC50	0.39 [1], 1.7 [2], 11.22 [3], 10000.0 [4]
	1-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-methylbutan-2-ol	IC50	0.71 [1], 3.71 [2], 104.71 [3], 10000.0 [4]
	1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]piperidin-4-ol	IC50	0.89 [1], 1.58 [2], 30.9 [3], 10000.0 [4]
	4-[(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)methyl]piperidin-4-ol	IC50	7.08 [1], 48.98 [2], 741.31 [3], 10000.0 [4]
	2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-N-(2-hydroxyethyl)acetamide	IC50	12.88 [1], 158.49 [2], 891.25 [3], 10000.0 [4]
	3-[Cyclopropylmethyl-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]amino]-5-methoxy-N-methylbenzamide	IC50	2.88 [1], 10.96 [2], 354.81 [3], 10000.0 [4]
	2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-N-(2-methoxyethyl)acetamide	IC50	30.9 [1], 128.82 [2], 2290.87 [3], 10000.0 [4]
	N-[3-(3,3-Difluoroazetidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine	IC50	3.24 [1], 4.17 [2], 177.83 [3], 10000.0 [4]
	2-[4-[7-[N-(3-Aminopropyl)-3,5-dimethoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanol	IC50	0.81 [1], 1.7 [2], 141.25 [3], 10000.0 [4]
	N-(3,5-Dimethoxyphenyl)-N-[2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]ethyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine	IC50	2.63 [1], 10.96 [2], 158.49 [3], 10000.0 [4]
	3-[[3-[1-(2-Hydroxyethyl)pyrazol-4-yl]quinoxalin-6-yl]-(3-hydroxypropyl)amino]-5-methoxy-N-methylbenzamide	IC50	1.7 [1], 229.09 [2], 1380.38 [3], 10000.0 [4]
	N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-amine	IC50	1.91 [1], 26.3 [2], 213.8 [3], 10000.0 [4]
	2-(2-Chloro-3,5-dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethanol	IC50	0.68 [1], 1.55 [2], 22.39 [3], 10000.0 [4]
	3-[3-(2-Hydroxyethoxy)-5-methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino]propan-1-ol	IC50	3.02 [1], 26.3 [2], 478.63 [3], 10000.0 [4]
	2-[3-Methoxy-5-[[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-(3-pyrrolidin-1-ylpropyl)amino]phenoxy]ethanol	IC50	2.19 [1], 6.61 [2], 79.43 [3], 10000.0 [4]
	1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]piperidine-3-carbonitrile	IC50	1.51 [1], 3.8 [2], 72.44 [3], 10000.0 [4]
	[(2S)-1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-2-yl]methanol	IC50	0.62 [1], 1.82 [2], 25.7 [3], 10000.0 [4]
	2-[4-[7-[3-Fluoro-N-(2-hydroxyethyl)-5-methoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanol	IC50	3.8 [1], 19.95 [2], 851.14 [3], 10000.0 [4]
	Erdafitinib	IC50	3.8 [1], 5.0 [2], 15.85 [3]
	Debio-1347	IC50	22.0 [1]
	N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[4-(diethylamino)butylamino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamide	IC50	5.99 [1], 6.0 [2], 11.9 [3]
	2-[3-Methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-5-(trideuteriomethoxy)anilino]ethanol	IC50	0.89 [1], 134.9 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N-propan-2-yl-N'-[3-[1-(trideuteriomethyl)pyrazol-4-yl]quinoxalin-6-yl]ethane-1,2-diamine	IC50	2.88 [1], 13.8 [2], 7413.1 [3]
	N'-[3-Methoxy-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine	IC50	2.75 [1], 14.13 [2], 7943.28 [3]
	N'-[3-Fluoro-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine	IC50	9.77 [1], 616.6 [2], 10000.0 [3]
	N'-[3,5-Bis(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamine	IC50	7.59 [1], 204.17 [2], 10000.0 [3]
	3-[N-[3-(1-Methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-ol	IC50	0.95 [1], 41.69 [2], 10000.0 [3]
	N-[3,5-Bis(trideuteriomethoxy)phenyl]-3-(1-propan-2-ylpyrazol-4-yl)-N-(3-pyridin-4-ylprop-2-ynyl)quinoxalin-6-amine	IC50	6.17 [1], 10.96 [2], 8317.64 [3]
	N-[3,5-Bis(trideuteriomethoxy)phenyl]-1,1,2,2,3,3-hexadeuterio-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N'-(2,2,2-trifluoroethyl)propane-1,3-diamine	IC50	9.12 [1], 177.83 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamine;hydrochloride	IC50	5.25 [1], 165.96 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N'-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochloride	IC50	3.02 [1], 125.89 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-N-[3-(2,5-dimethylimidazol-1-yl)propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	7.76 [1], 524.81 [2], 10000.0 [3]
	2-[4-[7-[3,5-Dimethoxy-N-[2-(methylamino)ethyl]anilino]quinoxalin-2-yl]pyrazol-1-yl]-N-methylacetamide;hydrochloride	IC50	4.68 [1], 125.89 [2], 10000.0 [3]
	N-[(2-Aminophenyl)methyl]-N'-(3,5-dimethoxycyclohexa-2,4-dien-1-yl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine	IC50	13.8 [1], 154.88 [2], 10000.0 [3]
	3-[4-[3-[4-[7-[N-(Cyclopropylmethyl)-3,5-dimethoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]propyl]piperazin-1-yl]propan-1-ol;hydrochloride	IC50	2.88 [1], 870.96 [2], 4677.35 [3]
	2-[4-[7-[3,5-Dimethoxy-N-[2-(propan-2-ylamino)ethyl]anilino]quinoxalin-2-yl]pyrazol-1-yl]-N-methylacetamide;hydrochloride	IC50	4.9 [1], 20.42 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(oxolan-2-ylmethyl)ethane-1,2-diamine;hydrochloride	IC50	5.37 [1], 63.1 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N-methyl-N'-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochloride	IC50	2.95 [1], 61.66 [2], 10000.0 [3]
	N'-(3,4-Difluoro-5-methoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamine;hydrochloride	IC50	346.74 [1], 10000.0 [2]
	(2S)-1-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-(propan-2-ylamino)propan-2-ol;hydrochloride	IC50	3.31 [1], 21.38 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(3-piperidin-1-ylpropyl)quinoxalin-6-amine;hydrochloride	IC50	1.15 [1], 23.44 [2], 10000.0 [3]
	1,1,2,2,3,3-Hexadeuterio-3-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-ol	IC50	2.04 [1], 61.66 [2], 10000.0 [3]
	N-[(5-Chlorothiophen-2-yl)methyl]-N-(3,5-dimethoxyphenyl)-3-[1-(2-piperazin-1-ylethyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochloride	IC50	4.27 [1], 912.01 [2], 3162.28 [3]
	N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-[3-[(2S)-2-methylpyrrolidin-1-yl]propyl]quinoxalin-6-amine;hydrochloride	IC50	1.7 [1], 8.32 [2], 10000.0 [3]
	N'-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]-N'-propan-2-ylpropane-1,3-diamine;hydrochloride	IC50	12.3 [1], 154.88 [2], 5248.07 [3]
	N-(3,5-Dimethoxyphenyl)-N-[3-(2-methylpiperidin-1-yl)propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	2.4 [1], 12.02 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-N-[3-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	3.55 [1], 8.13 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-N-[2-(2,4-dimethylimidazol-1-yl)ethyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	53.7 [1], 1318.26 [2], 10000.0 [3]
	N-(2-Chloro-3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-1-ylpropyl)quinoxalin-6-amine;hydrochloride	IC50	4.27 [1], 11.48 [2], 8128.31 [3]
	N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(2-piperazin-1-ylethyl)quinoxalin-6-amine;hydrochloride	IC50	4.68 [1], 199.53 [2], 9772.37 [3]
	N'-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-N'-(3,5-dimethoxyphenyl)-N-(2,2,2-trifluoroethyl)propane-1,3-diamine;hydrochloride	IC50	3.8 [1], 489.78 [2], 9549.93 [3]
	2-[4-[7-[N-(Cyclopropylmethyl)-3-(2-hydroxyethoxy)-5-methoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanol;hydrochloride	IC50	3.39 [1], 489.78 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N-propan-2-yl-N'-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochloride	IC50	2.75 [1], 6.46 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-N-[(3-methoxypiperidin-3-yl)methyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine	IC50	7.94 [1], 933.25 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylpropane-1,3-diamine;hydrochloride	IC50	1.95 [1], 15.49 [2], 9332.54 [3]
	N-(Cyclopropylmethyl)-3-(1-methylpyrazol-4-yl)-N-[3-(trifluoromethoxy)phenyl]quinoxalin-6-amine;hydrochloride	IC50	10000.0 [1]
	N'-(3,5-Dimethoxyphenyl)-N-propan-2-yl-N'-[3-(1,3,5-trimethylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochloride	IC50	31.62 [1], 93.33 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(2-pyrazol-1-ylethyl)quinoxalin-6-amine;hydrochloride	IC50	2.29 [1], 426.58 [2], 10000.0 [3]
	N'-(3-Methoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine;hydrochloride	IC50	15.14 [1], 269.15 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N-methyl-N'-[3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-yl]ethane-1,2-diamine;hydrochloride	IC50	6.31 [1], 15.49 [2], 10000.0 [3]
	1-N-(3,5-Dimethoxyphenyl)-3-methyl-1-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-2-N-propan-2-ylbutane-1,2-diamine;hydrochloride	IC50	43.65 [1], 707.95 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N'-[3-(5-ethyl-1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine;hydrochloride	IC50	7.08 [1], 102.33 [2], 8317.64 [3]
	N'-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-N'-(3,5-dimethoxyphenyl)-N-propan-2-ylethane-1,2-diamine;2,2,2-trifluoroacetic acid	IC50	7.24 [1], 102.33 [2], 10000.0 [3]
	2-[(2S)-1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-2-yl]acetonitrile;hydrochloride	IC50	1.82 [1], 16.6 [2], 10000.0 [3]
	N-(3-Fluoro-5-methoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-pyrrolidin-1-ylpropyl)quinoxalin-6-amine;hydrochloride	IC50	1.95 [1], 234.42 [2], 6456.54 [3]
	N-[3-(3,6-Dihydro-2H-pyridin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	2.51 [1], 7.76 [2], 9120.11 [3]
	N-(3,5-Dimethoxyphenyl)-N-[3-[3-(methylamino)pyrrolidin-1-yl]propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	3.09 [1], 199.53 [2], 8317.64 [3]
	(2R)-1-(3,5-Dimethoxy-N-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-methoxypropan-2-ol;hydrochloride	IC50	1.1 [1], 34.67 [2], 10000.0 [3]
	N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-(3-morpholin-4-ylpropyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochloride	IC50	1.12 [1], 407.38 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(3-morpholin-4-ylpropyl)quinoxalin-6-amine;hydrochloride	IC50	2.24 [1], 20.89 [2], 10000.0 [3]
	2-(N-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-3,5-dimethoxyanilino)ethanol;hydrochloride	IC50	1.32 [1], 128.82 [2], 10000.0 [3]
	N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)quinoxalin-6-amine;hydrochloride	IC50	5.89 [1], 74.13 [2], 10000.0 [3]
	N'-(3,5-Dimethoxyphenyl)-N'-[3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine;hydrochloride	IC50	2.29 [1], 8.71 [2], 7762.47 [3]
	N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-(2-piperidin-4-ylethyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochloride	IC50	0.87 [1], 870.96 [2], 5623.41 [3]
	N-[3-(3,3-Difluoropyrrolidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochloride	IC50	6.61 [1], 144.54 [2], 10000.0 [3]
	2-[(3,5-Dimethoxycyclohexa-2,4-dien-1-yl)-[3-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]quinoxalin-6-yl]amino]ethanol	IC50	51.29 [1], 2238.72 [2], 10000.0 [3]
	N-[3-(3,3-Difluoropyrrolidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine;hydrochloride	IC50	14.45 [1], 812.83 [2], 10000.0 [3]
	(2R)-1-(N-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-3,5-dimethoxyanilino)-3-methoxypropan-2-ol;hydrochloride	IC50	1.41 [1], 102.33 [2], 10000.0 [3]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Fibroblast growth factor receptor 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/fibroblast-growth-factor-receptor-3-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Fibroblast growth factor receptor 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/fibroblast-growth-factor-receptor-3-inhibitors-ic50-ki.
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