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Flap endonuclease 1 Inhibitors (IC50, Ki)
Structure
Compound Name
Standard Type
Standard Values (in nM)
3-Hydroxyquinazoline-2,4(1H,3H)-dioneIC500.08 [1], 300.0 [2]
3-Hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dioneIC500.03 [1], 9.0 [2]
3-Hydroxy-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-dioneIC500.01 [1], 3.0 [2]
3-Hydroxy-7-(4-methylphenyl)furo[3,2-d]pyrimidine-2,4(1H,3H)-dioneIC500.08 [1], 57.0 [2]
1-Benzyl-3-hydroxythieno[2,3-d]pyrimidine-2,4(1H,3H)-dioneIC500.23 [1], 680.0 [2]

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References
This online resource may be cited as follows
MLA
"Quest Database™ Flap endonuclease 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 11 Feb. 2026, https://www.aatbio.com/data-sets/flap-endonuclease-1-inhibitors-ic50-ki.
APA
AAT Bioquest, Inc. (2026, February 11). Quest Database™ Flap endonuclease 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/flap-endonuclease-1-inhibitors-ic50-ki.
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