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Formyl peptide receptor 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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Methionine benzimidazole 6IC50158.49 [1], 501.19 [2], 3162.28 [3]
Diamide 7IC50398.11 [1], 1584.89 [2]
N-Formyl-methionyl-leucyl-phenylalanineIC5020.0 [1]
N-Formyl-methionyl-leucyl-phenylalanineKi42.0 [1]
5-[(4-Cyanophenyl)sulfonylamino]-N-[(2S)-3,3-dimethylbutan-2-yl]-1-(4-fluorophenyl)-3-methylpyrazole-4-carboxamideIC5025.12 [1]
N-[(2S)-3,3-Dimethylbutan-2-yl]-3-methyl-5-[(4-methylphenyl)sulfonylamino]-1-phenylpyrazole-4-carboxamideIC5079.43 [1]
(2S)-2-[[(2R)-4-Methyl-2-[[(2S)-2-[[(2R)-4-methyl-2-[[(2S)-3-phenyl-2-(propan-2-ylcarbamoylamino)propanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC50200.0 [1], 500.0 [2]
(2S)-2-[[(2R)-4-Methyl-2-[[(2S)-2-[[(2R)-4-methyl-2-[[(2S)-2-[(3-methylphenyl)carbamoylamino]-3-phenylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC5020.0 [1], 200.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-(Benzylcarbamoylamino)-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC50600.0 [1], 800.0 [2]
(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-(Carbamoylamino)-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC50100.0 [1], 800.0 [2]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-4-methylsulfanyl-2-(propan-2-ylcarbamoylamino)butanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC502000.0 [1], 5000.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-(1-Adamantylcarbamoylamino)-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC50900.0 [1], 2000.0 [2]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-4-methylsulfanyl-2-(propylcarbamoylamino)butanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC502000.0 [1], 3000.0 [2]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-2-(2-methylpropylcarbamoylamino)-4-methylsulfanylbutanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC501000.0 [1], 4000.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-(Ethylcarbamoylamino)-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC501000.0 [1], 3000.0 [2]
(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-(Butylcarbamoylamino)-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC50300.0 [1], 600.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-(Tert-butylcarbamoylamino)-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC502000.0 [1], 3000.0 [2]
(2S)-2-[[(2R)-4-Methyl-2-[[(2S)-2-[[(2R)-4-methyl-2-[[(2S)-3-phenyl-2-(phenylcarbamoylamino)propanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC5050.0 [1], 500.0 [2]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-2-(methylcarbamoylamino)-4-methylsulfanylbutanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC502000.0 [1], 3000.0 [2]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-2-[(3-methylphenyl)carbamoylamino]-4-methylsulfanylbutanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC50100.0 [1], 1600.0 [2]
(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-(1-Adamantylcarbamoylamino)-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC5020.0 [1], 300.0 [2]
Cyclosporin AIC5010000.0 [1]
SulfinpyrazoneIC5010000.0 [1]
Butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanineIC502000.0 [1]
Boc-Met-Leu-Phe-OHIC502511.89 [1]
[6-Ethyl-2-methyl-3-(1-methylbenzimidazol-2-yl)-4-oxochromen-7-yl] acetateKi100.0 [1]
N-[1-(1H-Benzimidazol-2-yl)-3-(methylsulfanyl)propyl]cyclohexanecarboxamideIC502511.89 [1]
CID 46897162IC505000.0 [1]
Group E 1682-2106 [PMID:16118363]IC505011.87 [1]
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazoleKi10000.0 [1]
(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-33-[(E)-3-methylhept-5-en-2-yl]-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC50150.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-24-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC509200.0 [1]
(3S,6S,9R,12S,15R,18R,21R,27S,33S)-27-[(1R)-1-Hydroxyethyl]-30-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,9,12,16,22,25-octamethyl-3,6,15,21-tetrakis(2-methylpropyl)-18,33-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC505500.0 [1]
(3S,6S,9S,12R,15S,18R,21S,24R,30S,33S)-21-[(2S)-Butan-2-yl]-30-[(1R)-1-hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3-propan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC502300.0 [1]
(3S,6S,9S,12R,15S,18R,21S,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,21,24-pentakis(2-methylpropyl)-3-propan-2-yl-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-(Cyclohexylmethyl)-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC506330.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-33-[(E,2R)-2-methylhex-4-enyl]-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-[(1R)-1-Hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21S,24R,30S,33S)-30-[(1R)-1-Hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,6,10,12,15,19,25,28-nonamethyl-9,18,21,24-tetrakis(2-methylpropyl)-3-propan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC503250.0 [1]
(3S,6S,9S,12R,15S,18S,21R,24R,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,25,28-heptamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC501800.0 [1]
(3S,6R,9S,12R,15R,18R,24S,27S,30S,33S)-24-[(1R)-1-Hydroxyethyl]-27-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,6,9,13,19,22,28-octamethyl-3,12,18,33-tetrakis(2-methylpropyl)-15,30-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9R,12S,15S,21S,24S,27S,30S,33S)-3-Hydroxy-21-[(1R)-1-hydroxyethyl]-24-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,6,10,19,25,28-hexamethyl-9,12,15,30,33-pentakis(2-methylpropyl)-3,27-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC50560.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-24-[(2S)-Butan-2-yl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,28-octamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC505000.0 [1]
(3S,6S,9S,12R,15S,18R,21S,24R,30S,33S)-30-[(1R)-1-Hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,19,25,28-octamethyl-6,9,18,21,24-pentakis(2-methylpropyl)-3-propan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC50590.0 [1]
(3S,6S,9S,12R,15S,18R,21S,24R,30S,33S)-1,4,7,10,12,15,19,25,28-Nonamethyl-6,9,18,24,33-pentakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-24-[(2S)-Butan-2-yl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC507000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-12-(4-Aminobutyl)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC506300.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-12-(hydroxymethyl)-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9R,12S,15R,21S,24S,27S,30S,33S)-24-[(E,1R,2R)-1,6-Dihydroxy-2-methylhex-4-enyl]-3-hydroxy-21-[(1R)-1-hydroxyethyl]-1,6,10,16,19,25,28-heptamethyl-9,12,15,30,33-pentakis(2-methylpropyl)-3,27-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC501480.0 [1]
(3S,6S,9R,12S,15R,21S,24S,27S,30S,33S)-3-Hydroxy-21-[(1R)-1-hydroxyethyl]-24-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,6,10,16,19,25,28-heptamethyl-9,15,30,33-tetrakis(2-methylpropyl)-3,12,27-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC502500.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-12-(hydroxymethyl)-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,15,19,25-heptamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC505000.0 [1]
(3S,6S,9R,12S,15R,18R,21R,27S,33S)-27-Ethyl-30-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,9,12,16,22,25-octamethyl-3,6,15,21-tetrakis(2-methylpropyl)-18,33-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC506450.0 [1]
(3S,6S,9S,12R,15S,18R,21S,24R,30S,33S)-1,4,7,10,12,15,19,25,28-Nonamethyl-6,9,18,24,33-pentakis(2-methylpropyl)-3,21,30-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,7,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21,30-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-[(1R)-1-Hydroxyethyl]-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC503000.0 [1]
(3S,6R,9S,12R,15R,18R,24S,27S,30S,33S)-24-Ethyl-27-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,6,9,13,19,22,28-octamethyl-3,12,18,33-tetrakis(2-methylpropyl)-15,30-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-33-hexyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18S,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,19,25,28,30-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC502200.0 [1]
(3S,6S,9R,12S,15R,21S,24S,27S,30S,33S)-3-Hydroxy-21-[(1R)-1-hydroxyethyl]-24-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,6,10,16,25,28-hexamethyl-9,12,15,30,33-pentakis(2-methylpropyl)-3,27-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC50300.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-3-[(2S)-Butan-2-yl]-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-21-propan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9R,12S,15R,21S,24S,27S,30S,33S)-3-Hydroxy-21-[(1R)-1-hydroxyethyl]-24-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,6,10,16,19,25,28-heptamethyl-9,12,15,30,33-pentakis(2-methylpropyl)-3,27-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC50570.0 [1]
(3S,6S,9R,12S,15R,18R,21R,27S,33S)-30-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,7,9,12,16,22,25-octamethyl-3,6,15,21-tetrakis(2-methylpropyl)-18,27,33-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,18R,21S,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3-propan-2-yl-21,30-dipropyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC503400.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21,30-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC503000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,15,19,25,28,30-decamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9R,12S,15R,21S,24S,27S,30S,33S)-12-[(2S)-Butan-2-yl]-3-hydroxy-21-[(1R)-1-hydroxyethyl]-24-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,6,10,16,19,25,28-heptamethyl-9,15,30,33-tetrakis(2-methylpropyl)-3,27-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC50750.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC503000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-[(E,1R,2R)-1-Hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC503000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21,24-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC505000.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,3,4,7,10,12,15,19,25,28-decamethyl-6,9,18,24-tetrakis(2-methylpropyl)-21-propan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC502520.0 [1]
(3S,6S,9S,12R,15S,18R,21R,24S,30S,33S)-24-Benzyl-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhept-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeIC5010000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-(Butylcarbamoylamino)-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC50300.0 [1]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-4-methylsulfanyl-2-(phenylcarbamoylamino)butanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC5030.0 [1]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-2-[(4-methylphenyl)carbamoylamino]-4-methylsulfanylbutanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC502.0 [1]
(2S)-2-[[(2S)-4-Methyl-2-[[(2S)-4-methylsulfanyl-2-(prop-1-en-2-ylcarbamoylamino)butanoyl]amino]pentanoyl]amino]-3-phenylpropanoic acidIC50300.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[(4-Chlorophenyl)carbamoylamino]-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC502.0 [1]
(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-3-(4-Benzoylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-4-methylpentanoyl]amino]-3-(cyclohexen-1-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC50140.0 [1]
N-Cyclopropyl-2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxamideKi10000.0 [1]
Azepan-1-yl-(2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)methanoneKi10000.0 [1]
N-Benzyl-2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxamideKi10000.0 [1]
(2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)-pyrrolidin-1-ylmethanoneKi10000.0 [1]
(4-Benzylpiperazin-1-yl)-(2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)methanoneKi10000.0 [1]
Morpholino(2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)methanoneKi10000.0 [1]
Ethyl 2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylateKi10000.0 [1]
CID 136118025Ki10000.0 [1]
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acidKi10000.0 [1]
(2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)-piperidin-1-ylmethanoneKi10000.0 [1]
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxamideKi10000.0 [1]
N-[1-(1H-Benzimidazol-2-yl)-3-methylsulfanylpropyl]pyrazine-2-carboxamideIC5010000.0 [1]
N-[2-(2,6-Dimethylanilino)-2-oxo-1-phenylethyl]-2-hydroxybenzamideIC501258.93 [1]
N-[1-(1-Benzyl-1H-benzimidazol-2-yl)-3-(methylsulfanyl)propyl]benzamideIC502511.89 [1]
N-[1-[1-[(4-Cyanophenyl)methyl]benzimidazol-2-yl]-3-methylsulfanylpropyl]benzamideIC50316.23 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-(Carbamoylamino)-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC502000.0 [1]
2-[[(2S)-2-[[(2S)-2-[(4-Methoxyphenyl)carbamoylamino]-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acidIC502.0 [1]
N-{1-(4-Chlorophenyl)-2-[(2,6-dimethylphenyl)amino]-2-oxoethyl}-2-hydroxybenzamideIC50794.33 [1]
N-[1-(1H-Benzimidazol-2-yl)-3-methylsulfanylpropyl]-3-methylfuran-2-carboxamideIC503981.07 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Formyl peptide receptor 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/formyl-peptide-receptor-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Formyl peptide receptor 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/formyl-peptide-receptor-1-inhibitors-ic50-ki.
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