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Free fatty acid receptor 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
2-Fluoro-4-[3-(2,6-dimethylphenyl)benzyloxy]benzenepropanoic acidKi32.0 [1]
2-[6-[[3-[4-(2-Ethoxyethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi32.0 [1]
2-[6-[[3-(2,6-Dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi170.0 [1]
CID 46869922Ki38.0 [1]
8-[[3-(2,6-Dimethylphenyl)phenyl]methoxy]-2,3,4,5-tetrahydro-1-benzoxepine-4-carboxylic acidKi270.0 [1]
2-[5-[[3-(2,6-Dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1H-inden-1-yl]acetic acidKi210.0 [1]
{6-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-1,2,3,4-tetrahydronaphthalen-1-yl}acetic acidKi59.0 [1]
2-[6-[[3-(2,6-Dimethylphenyl)phenyl]methoxy]-1-benzofuran-3-yl]acetic acidKi10000.0 [1]
2-[2-[[3-(2,6-Dimethylphenyl)phenyl]methoxy]-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]acetic acidKi2400.0 [1]
FasiglifamKi28.84 [1]
3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acidKi218.78 [1]
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acidKi41.69 [1]
3-(4-(o-Tolylethynyl)phenyl)propanoic acidKi630.96 [1]
Lad0ZG7ffoKi4.7 [1]
5-[[4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy-2-methylphenyl]methyl]-1,3-thiazolidine-2,4-dioneKi69.18 [1]
3-[4-[[3-(2-Methylphenyl)phenyl]methylamino]phenyl]propanoic acidKi5.89 [1]
3-(4-Benzyloxyphenyl)propionic acidKi13803.84 [1]
3-[4-[[3-(2,6-Dimethylphenyl)phenyl]methoxy]phenyl]propanoic acidKi46.0 [1]
4-Methyl-N-(9H-xanthen-9-yl)benzenesulfonamideIC5025118.86 [1]
3-(4-((2-(Cyanomethyl)phenyl)ethynyl)-2-fluorophenyl)propanoic acidKi85.11 [1]
3-[2-Fluoro-4-[[3-[4-[(4-hydroxy-1,1-dioxothian-4-yl)methoxy]-2,6-dimethylphenyl]phenyl]methylamino]phenyl]propanoic acidKi19.0 [1]
N-(4-Butylphenyl)-4-fluorobenzenesulfonamideIC508128.31 [1]
3-[2-Fluoro-4-[[3-[2-methyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methylamino]phenyl]propanoic acidKi4.37 [1]
3-[4-[2-[2-(Cyanomethyl)phenyl]ethynyl]phenyl]propanoic acidKi204.17 [1]
(3S)-3-[4-[[5-[(8-Methoxy-3,4-dihydro-2H-quinolin-1-yl)methyl]thiophen-2-yl]methoxy]phenyl]hex-4-ynoic acidKi27.0 [1]
5-Octyl-1,3-thiazolidine-2,4-dioneIC507900.0 [1]
Unii-2OH4ruc1V4Ki15.0 [1]
4-Fluoro-N-methyl-N-(4-phenoxyphenyl)benzenesulfonamideIC5010715.19 [1]
3-[4-[[3-(2,6-Dimethyl-4-phenylmethoxyphenyl)phenyl]methoxy]phenyl]propanoic acidKi15.0 [1]
3-[4-[[3-[4-(1,1-Dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acidKi16.0 [1]
3-[4-[[3-[4-(2-Ethylsulfonylethoxy)-2,6-dimethylphenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acidKi15.0 [1]
3-[4-[[3-[2,6-Dimethyl-4-(oxan-4-yloxy)phenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acidKi20.0 [1]
3-[2-Fluoro-4-[[3-[4-[(4-hydroxy-1,1-dioxothian-4-yl)methoxy]-2,6-dimethylphenyl]phenyl]methoxy]phenyl]propanoic acidKi19.0 [1]
3-[4-[[3-[2,6-Dimethyl-4-[3-(2-oxopyrrolidin-1-yl)propoxy]phenyl]phenyl]methoxy]-2-fluorophenyl]propanoic acidKi21.0 [1]
(3S)-3-[4-[[2-[2,6-Dimethyl-4-(3-methylsulfonylpropoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acidKi63.0 [1]
(3S)-3-[4-[[2-(4-Cyanophenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acidKi35.0 [1]
(3S)-3-[4-[[2-[4-(3-Hydroxy-3-methylbutoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acidKi37.0 [1]
(3S)-3-[4-[[2-[4-(2-Methoxyethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acidKi102.0 [1]
(3S)-3-[4-[[2-(4-Propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acidKi32.0 [1]
(3S)-3-[4-[[2-[4-(Difluoromethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acidKi60.0 [1]
3-[4-[[3-[4-(2-Ethylsulfonylethoxy)-2,6-dimethylphenyl]phenyl]methylamino]-2-fluorophenyl]propanoic acidKi20.0 [1]
3-[4-[[3-[4-(1,1-Dioxothian-4-yl)oxy-2,6-dimethylphenyl]phenyl]methylamino]-2-fluorophenyl]propanoic acidKi18.0 [1]
2-[(2S,4S)-1-[4-[[4-(2-Fluoro-5-methoxyphenyl)-2-methylphenyl]methyl]phenyl]-4-(trifluoromethyl)pyrrolidin-2-yl]acetic acidKi45.0 [1]
2-(3-Chloro-5-pyridin-2-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxideIC50100000.0 [1]
2-(3-Pyridin-2-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxideIC50100000.0 [1]
2-(3-Phenoxyphenyl)-3H-1,2-benzothiazole 1,1-dioxideIC50173.78 [1]
2-[3-Fluoro-5-(4-methylphenoxy)phenyl]-3H-1,2-benzothiazole 1,1-dioxideIC502884.03 [1]
3-[3-(1,1-Dioxo-3H-1,2-benzothiazol-2-yl)-5-fluorophenoxy]benzonitrileIC503388.44 [1]
2-[3-(1,1-Dioxo-3H-1,2-benzothiazol-2-yl)-5-fluorophenoxy]benzonitrileIC50100000.0 [1]
2-(3-Fluoro-5-phenoxyphenyl)-3H-1,2-benzothiazole 1,1-dioxideIC503890.45 [1]
2-[3-[3-(1,1-Dioxo-3H-1,2-benzothiazol-2-yl)-5-fluorophenoxy]phenyl]acetonitrileIC5019952.62 [1]
4-[3-(1,1-Dioxo-3H-1,2-benzothiazol-2-yl)-5-fluorophenoxy]benzonitrileIC50616.6 [1]
2-[3-Fluoro-5-(2-methylphenoxy)phenyl]-3H-1,2-benzothiazole 1,1-dioxideIC5044668.36 [1]
2-(3-Fluoro-5-pyridin-4-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxideIC50100000.0 [1]
2-[3-Fluoro-5-(3-methylphenoxy)phenyl]-3H-1,2-benzothiazole 1,1-dioxideIC5025118.86 [1]
2-[(2S,4S)-1-[4-[3-[(2-Fluoro-5-methoxyphenyl)methyl]-2-methylphenoxy]phenyl]-4-(trifluoromethyl)pyrrolidin-2-yl]acetic acidKi49.0 [1]
2-[(2S)-1-[4-[[4-(2-Fluoro-5-methoxyphenyl)-2-methylphenyl]methyl]phenyl]pyrrolidin-2-yl]acetic acidKi310.0 [1]
2-[(2S)-2-Methyl-1-[4-[(2-methylphenyl)methyl]phenyl]pyrrolidin-2-yl]acetic acidKi23000.0 [1]
2-[(2S)-1-[6-[(2-Methylphenyl)methoxy]pyridin-3-yl]pyrrolidin-2-yl]acetic acidKi1800.0 [1]
2-[(2S,4R)-1-[4-[(2-Methylphenyl)methyl]phenyl]-4-phenylpyrrolidin-2-yl]acetic acidKi25000.0 [1]
2-[(2S)-1-[4-(2-Methylbenzoyl)phenyl]pyrrolidin-2-yl]acetic acidKi33000.0 [1]
(3S)-3-[4-[(5-Spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylthiophen-2-yl)methoxy]phenyl]hex-4-ynoic acidKi8.2 [1]
Ethyl 6-[6-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]naphthalen-2-yl]oxyhexanoateIC506300.0 [1]
3-(4-Nitrophenoxy)-N-phenylbenzamideIC505300.0 [1]
3-[4-[[3-(2,6-Dimethylphenyl)-4-methoxyphenyl]methoxy]phenyl]propanoic acidKi47.0 [1]
3-[4-[[5-(2,6-Dimethylphenyl)-2-methoxyphenyl]methoxy]phenyl]propanoic acidKi520.0 [1]
3-[4-[[3-(2,6-Dimethylphenyl)-2-methylphenyl]methoxy]phenyl]propanoic acidKi58.0 [1]
2-[6-[[3-(1-Benzothiophen-3-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi290.0 [1]
2-[6-[[3-(1-Benzothiophen-5-yl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi570.0 [1]
2-[6-[[3-(2,6-Dimethyl-4-phenylmethoxyphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi18.0 [1]
2-[6-[[3-(2,4-Dimethylphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi57.0 [1]
2-[6-[[3-(2,6-Dimethylphenyl)-4-methoxyphenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi130.0 [1]
2-[6-[[3-(2,6-Dimethylphenyl)-4-phenylmethoxyphenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi6.9 [1]
{5-[(2',6'-Dimethylbiphenyl-3-yl)methoxy]-1H-indol-1-yl}acetic acidKi10000.0 [1]
2-[6-[[3-(2,4,6-Trimethylphenyl)phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi36.0 [1]
(6-{[3-(2-Methyl-1-naphthyl)benzyl]oxy}-2,3-dihydro-1-benzofuran-3-yl)acetic acidKi41.0 [1]
2-[(3S)-6-[[3-[3-Fluoro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi18.0 [1]
2-[(3S)-6-[[3-[4-[(4-Hydroxy-1,1-dioxothian-4-yl)methoxy]-2,6-dimethylphenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi24.0 [1]
2-[(3S)-6-[[3-[3-Chloro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi19.0 [1]
2-[(3S)-6-[[3-[3,5-Dichloro-2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acidKi12.0 [1]
(3R,4R)-3-(4-Methoxyphenyl)-1-oxo-2-propyl-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acidIC502100.0 [1]
(3R,4R)-3-(1-Benzofuran-2-yl)-2-[(2S)-2-methylbutyl]-1-oxo-3,4-dihydroisoquinoline-4-carboxylic acidIC5020.0 [1]
(3R,4R)-3-[4-(4-Methylcyclohexyl)oxyphenyl]-1-oxo-2-propyl-3,4-dihydroisoquinoline-4-carboxylic acidIC5010.0 [1]
(3R,4R)-2-Ethyl-1-oxo-3-(4-phenoxyphenyl)-3,4-dihydroisoquinoline-4-carboxylic acidIC5012.0 [1]
(3R,4R)-1-Oxo-3-(4-phenylmethoxyphenyl)-2-propyl-3,4-dihydroisoquinoline-4-carboxylic acidIC5096.0 [1]
(3R,4R)-3-[4-(3,5-Dimethylphenoxy)phenyl]-1-oxo-2-propyl-3,4-dihydroisoquinoline-4-carboxylic acidIC502.0 [1]
(3R,4R)-3-[4-(3,4-Dimethylphenoxy)phenyl]-1-oxo-2-propyl-3,4-dihydroisoquinoline-4-carboxylic acidIC503.0 [1]
(3R,4R)-1-Oxo-2-propyl-3-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-3,4-dihydroisoquinoline-4-carboxylic acidIC5029.0 [1]
(3R,4R)-2-Methyl-1-oxo-3-(4-phenoxyphenyl)-3,4-dihydroisoquinoline-4-carboxylic acidIC50156.0 [1]
(3R,4R)-2-(Cyclopropylmethyl)-1-oxo-3-(4-phenoxyphenyl)-3,4-dihydroisoquinoline-4-carboxylic acidIC504.0 [1]
(3R,4R)-3-(3,4-Dichlorophenyl)-1-oxo-2-propyl-3,4-dihydroisoquinoline-4-carboxylic acidIC5089.0 [1]
(3R,4R)-3-(3-Chlorophenyl)-1-oxo-2-propyl-3,4-dihydroisoquinoline-4-carboxylic acidIC50228.0 [1]
(3R,4R)-3-(1-Benzofuran-2-yl)-1-oxo-2-propyl-3,4-dihydroisoquinoline-4-carboxylic acidIC50119.0 [1]
(3R,4R)-3-(3,4-Dichlorophenyl)-2-[(2S)-2-methylbutyl]-1-oxo-3,4-dihydroisoquinoline-4-carboxylic acidIC5013.0 [1]
(3R,4R)-3-(3,4-Dichlorophenyl)-2-(2-ethylbutyl)-1-oxo-3,4-dihydroisoquinoline-4-carboxylic acidIC5010.0 [1]
(3R,4R)-3-(1,3-Benzothiazol-2-yl)-2-(2-ethylbutyl)-1-oxo-3,4-dihydroisoquinoline-4-carboxylic acidIC5010.0 [1]
4-Methyl-N-(4-phenoxyphenyl)benzenesulfonamideIC5010000.0 [1]
2-(3-Fluoro-5-pyridin-3-yloxyphenyl)-3H-1,2-benzothiazole 1,1-dioxideIC50100000.0 [1]
2-[(2S,4S)-1-[4-(4-Methoxy-2-methylphenoxy)phenyl]-4-(trifluoromethyl)pyrrolidin-2-yl]acetic acidKi39.0 [1]
Rac-3-(4-(2-(difluoromethoxy)-4-(trifluoromethyl)phenoxy)phenyl)hex-4-ynoic acidIC5012.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Free fatty acid receptor 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/free-fatty-acid-receptor-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Free fatty acid receptor 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/free-fatty-acid-receptor-1-inhibitors-ic50-ki.
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