G protein-coupled receptor kinase 6 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	3-Methyl-8-(3-morpholin-4-ylpropyliminomethyl)-5-propan-2-yl-2-[1,6,7-trihydroxy-3-methyl-8-(3-morpholin-4-ylpropyliminomethyl)-5-propan-2-ylnaphthalen-2-yl]naphthalene-1,6,7-triol	IC50	10120.0 [1], 16890.0 [2]
	Staurosporine	IC50	34000.0 [1]
	Baicalein	IC50	8700.0 [1]
	N-(2-(4-Bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	IC50	7000000.0 [1]
	Bisindolylmaleimide IX	IC50	350000.0 [1]
	Scutellarein	IC50	6610.0 [1]
	Doramapimod	IC50	30000.0 [1]
	Balanol	IC50	490.0 [1]
	Perimidine	IC50	12540.0 [1]
	CID 11677079	IC50	30000.0 [1]
	N-{4-[4-(4-Hydroxy-phenyl)-phthalazin-1-ylamino]-phenyl}-acetamide	IC50	60000.0 [1]
	2,7-Diamino-4-(4-methylphenyl)-4H-chromene-3-carbonitrile	IC50	25960.0 [1]
	3-Ethyl-1-(2-hydroxy-ethyl)-1-(6-oxo-5,6-dihydro-[1,3]dioxolo[4,5-g]quinolin-7-ylmethyl)-thiourea	IC50	60000.0 [1]
	7,8-Dihydroxy-4-(4-methoxyphenyl)-2H-chromen-2-one	IC50	7160.0 [1]
	5-(Diethylamino)-2-(2,3-dihydro-1H-perimidin-2-yl)phenol	IC50	8440.0 [1]
	4-(2,3-Dihydro-1H-benzo[f]cyclopenta[c]quinolin-4-yl)benzene-1,2-diol	IC50	28420.0 [1]
	Ethyl 5-[2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl]furan-2-carboxylate	IC50	7050.0 [1]
	3-Amino-5-(2-diethylamino-ethyl)-5H-pyrido[4,3-b]indole-4-carbonitrile	IC50	18750.0 [1]
	2-Amino-1-butyl-1H-pyrrolo[2,3-b]quinoxaline-3-carbonitrile	IC50	1560.0 [1]
	2-[(5-Thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetic acid	IC50	4600.0 [1]
	7-((Pyridin-2-ylamino)(pyridin-3-yl)methyl)quinolin-8-ol	IC50	6750.0 [1]
	N1-(4-(2-Methylimidazo[1,2-a]pyridin-3-yl)	IC50	60000.0 [1]
	1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)urea	IC50	30000.0 [1]
	6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	10000.0 [1]
	2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-one	IC50	10000.0 [1]
	N-Benzyl-3-[(3-pyridin-4-yl-1H-1,2,4-triazol-5-yl)methylamino]benzamide	IC50	30000.0 [1]
	N-Benzyl-3-[(4-methyl-3-pyridin-4-yl-1H-pyrazol-5-yl)methylamino]benzamide	IC50	30000.0 [1]
	3-(9-Oxa-3,4,6,12-tetrazatricyclo[8.4.0.02,6]tetradeca-1(10),2,4,11,13-pentaen-5-ylmethylamino)-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide	IC50	30000.0 [1]
	N-Benzyl-3-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)methylamino]benzamide	IC50	30000.0 [1]
	N-Methyl-3-[(3-pyridin-4-yl-1H-1,2,4-triazol-5-yl)methylamino]benzamide	IC50	30000.0 [1]
	Methyl 2-amino-1-hexyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate	IC50	1430.0 [1]
	2,7-Diamino-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile	IC50	11770.0 [1]
	7-(((4-Ethoxyphenyl)amino)(pyridin-2-yl)methyl)quinolin-8-ol	IC50	4480.0 [1]
	Pyridine, 3-(5-(p-methoxyphenyl)-2-oxazolyl)-	IC50	60000.0 [1]
	1-[[5-(3-Methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]propan-2-one	IC50	100000.0 [1]
	N,N-Dimethyl-2-[[5-(3-methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide	IC50	100000.0 [1]
	4-(Azepan-1-ylsulfonyl)-N-[2-(4-methylfuran-2-yl)phenyl]benzenesulfonamide	IC50	60000.0 [1]
	(5Z)-5-(3,4-Dihydroxybenzylidene)-2-[(2,3-dimethylphenyl)amino]-1,3-thiazol-4(5H)-one	IC50	7110.0 [1]
	4-[2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-yliden)hydrazino]-N~1~-(2-ethylhexyl)benzamide	IC50	60000.0 [1]
	2-[[5-(2-Hydroxy-5-methoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	4550.0 [1]
	2-[[5-(2-Hydroxy-5-methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	2710.0 [1]
	2-[[5-(3-Formyl-2-hydroxy-5-methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	45300.0 [1]
	3-[3-(Carboxymethylsulfanyl)-1H-1,2,4-triazol-5-yl]-4-hydroxybenzoic acid	IC50	100000.0 [1]
	2-[[5-(4-Hydroxy-2,6-dimethoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	100000.0 [1]
	2-[[5-(2-Hydroxy-6-methoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	100000.0 [1]
	4-[5-(2-Phenylethylamino)-1,3,4-thiadiazol-2-yl]phenol	IC50	60000.0 [1]
	2-[[5-(5-Bromo-2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	1050.0 [1]
	2-[[5-(3-Fluoro-4-hydroxy-5-methoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	3300.0 [1]
	2-[[5-(2-Hydroxy-4-methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	6880.0 [1]
	2-[[5-(2,4-Dihydroxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	11600.0 [1]
	2-[[5-(4-Hydroxy-3-methoxy-5-nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	15900.0 [1]
	2-[[5-[4-(Diethylamino)-2-hydroxyphenyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	25800.0 [1]
	2-[[5-(2-Hydroxy-3-methoxy-5-nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	34800.0 [1]
	2-[[5-(3-Fluoro-4-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	7300.0 [1]
	2-[[5-(2,5-Dihydroxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	6160.0 [1]
	2-[[5-(4-Hydroxy-3-nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	6800.0 [1]
	2-[[5-(3-Fluoro-2-hydroxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	8750.0 [1]
	2-[[5-(2-Hydroxy-4-methoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	20900.0 [1]
	N-(Furan-2-ylmethyl)-5-(4-phenylphenyl)-3,6-dihydro-1,3,4-thiadiazin-2-imine	IC50	10440.0 [1]
	2-[[5-(2-Hydroxy-5-nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	14100.0 [1]
	2-[[5-(3,4-Dihydroxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	5020.0 [1]
	2-[[5-(2-Hydroxy-3-nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	70000.0 [1]
	2-[[5-(4-Hydroxy-3,5-dimethoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	8830.0 [1]
	5-(4-Chloro-3-nitrophenyl)-N-(furan-2-ylmethyl)-3,6-dihydro-1,3,4-thiadiazin-2-imine	IC50	6620.0 [1]
	(5E)-5-(4-Hydroxy-3-methoxybenzylidene)-3-(pyridin-3-yl)-2-thioxo-1,3-thiazolidin-4-one	IC50	40620.0 [1]
	4-(Azepan-1-ylsulfonyl)-N-[4-(tetrazol-1-yl)phenyl]benzenesulfonamide	IC50	60000.0 [1]
	Methyl 2-amino-1-pentyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate	IC50	1030.0 [1]
	4-[(3As,4R,9bR)-8-iodo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid	IC50	6660.0 [1]
	2-[[5-(3-Methylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	1440.0 [1]
	2-[[5-(4-Methyl-3-nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	751.0 [1]
	2-[[5-(3-Fluorophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	4700.0 [1]
	4,4'-{[4-(Diethylamino)phenyl]methanediyl}bis(3-methyl-1H-pyrazol-5-ol)	IC50	9930.0 [1]
	Acetic acid, ((5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazol-3-yl)thio)-	IC50	8230.0 [1]
	1,4-Diamino-9,10-dioxoanthracene-2-carboxamide	IC50	12650.0 [1]
	2,7-Diamino-4-(6-chloro-[1,3]dioxolo[4,5-g]quinolin-7-yl)-4H-chromene-3-carbonitrile	IC50	6480.0 [1]
	7-{[(5-Methyl-1,2-oxazol-3-yl)amino](pyridin-2-yl)methyl}quinolin-8-ol	IC50	6450.0 [1]
	7-{[(4-Methoxyphenyl)amino](pyridin-2-yl)methyl}quinolin-8-ol	IC50	10260.0 [1]
	N-(6-Methyl-1,3-benzothiazol-2-yl)formamide	IC50	60000.0 [1]
	4-Amino-5-N-[2-(2-methoxyethylamino)-2-oxoethyl]-5-N-phenyl-1,2-thiazole-3,5-dicarboxamide	IC50	60000.0 [1]
	{[5-(3-Methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid	IC50	5850.0 [1]
	2-[[5-[3-(Trifluoromethyl)phenyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	3020.0 [1]
	2-[[5-(3-Nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	1400.0 [1]
	2-[[5-[4-(Dimethylamino)phenyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	100000.0 [1]
	2-[[5-(2,3-Dimethoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	100000.0 [1]
	2-[[5-(3,4-Difluorophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	3360.0 [1]
	2-[[5-(4-Methoxy-3-nitrophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	1050.0 [1]
	2-[[5-(3-Cyanophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	2310.0 [1]
	2-[[5-(3,5-Dimethoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	6100.0 [1]
	2-[[5-(3-Methylsulfonylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	6360.0 [1]
	2-[[5-(2,6-Dimethoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	100000.0 [1]
	2-[[4-Methyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]propanoic acid	IC50	100000.0 [1]
	(4S,12Ar)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide	IC50	1370.0 [1]
	2-[[5-(2,3-Difluorophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	10700.0 [1]
	2-[[5-(2,5-Dimethoxyphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	100000.0 [1]
	2-[[5-[4-(Trifluoromethoxy)phenyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	5920.0 [1]
	Methyl 2-amino-1-(prop-2-en-1-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate	IC50	973.0 [1]
	Ethyl 2-amino-1-cyclopropyl-1H-pyrrolo(2,3-B)quinoxaline-3-carboxylate	IC50	2830.0 [1]
	6-(3,4-Dihydroxy-phenyl)-8-ethoxy-1,3-dimethyl-cyclohepta[c]furan-4-one	IC50	4410.0 [1]
	2-[[5-(3-Piperidin-1-ylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetic acid	IC50	51800.0 [1]
	3-[3-(Carboxymethylsulfanyl)-1H-1,2,4-triazol-5-yl]-4-fluorobenzoic acid	IC50	81700.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ G protein-coupled receptor kinase 6 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/g-protein-coupled-receptor-kinase-6-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ G protein-coupled receptor kinase 6 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/g-protein-coupled-receptor-kinase-6-inhibitors-ic50-ki.
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