Name: Gamma-secretase Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Gamma-secretase Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	CID 11560787	IC50	83.0 ^[1]
	Semagacestat	IC50	39.81 ^[1]
	Begacestat	IC50	11.0 ^[1]
	Avagacestat	IC50	0.27 ^[1]
	(4S,4As,10bS)-7,10-difluoro-4-(2-methylsulfonylethyl)-10b-[4-(trifluoromethyl)phenyl]sulfonyl-2,4,4a,5-tetrahydro-1H-pyrano[3,4-c]chromene	IC50	11.0 ^[1]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Gamma-secretase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 17 Jan. 2026, https://www.aatbio.com/data-sets/gamma-secretase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2026, January 17). Quest Database™ Gamma-secretase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/gamma-secretase-inhibitors-ic50-ki.
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