Glutaminase kidney isoform, mitochondrial Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N,N'-[Sulfanediylbis(Ethane-2,1-Diyl-1,3,4-Thiadiazole-5,2-Diyl)]bis(2-Phenylacetamide)	IC50	200.0 [1]
	Telaglenastat	IC50	5.0 [1], 60.0 [2], 180.0 [3], 2200.0 [4]
	N-[5-[2-[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	2700.0 [1], 15000.0 [2]
	N-[5-[2-[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	Ki	2000.0 [1]
	(2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-(1,2,4-triazin-3-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	3.9 [1], 62.8 [2]
	(2R)-2-Methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide	IC50	0.21 [1], 43.36 [2]
	(2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	0.39 [1], 29.0 [2]
	(2S)-2-Methoxy-2-(4-methoxyphenyl)-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	0.4 [1], 31.0 [2]
	(2R)-2-(4-Fluoro-3-methoxyphenyl)-2-methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	4.99 [1], 70.69 [2]
	(2S)-2-(4-Fluorophenyl)-2-methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-3-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	175.1 [1], 2187.0 [2]
	(5Z)-5-{[1-(4-Bromophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylidene}-4-hydroxy-1,3-thiazol-2(5H)-one	IC50	3097.0 [1], 5373.0 [2]
	5-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-3-ethylphenyl]benzonitrile	IC50	59.0 [1], 92.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-methoxyphenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	66.0 [1], 177.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	48.0 [1], 148.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	243.0 [1], 355.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	39.0 [1], 87.0 [2]
	(5Z)-5-[[2-Chloro-4-[4-[3-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	57.0 [1], 255.0 [2]
	(5Z)-5-[[1-(4-Bromophenyl)-2,5-diphenylpyrrol-3-yl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	4896.0 [1], 8762.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	56.0 [1], 217.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	45.0 [1], 151.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-hydroxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	247.0 [1], 760.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	49.0 [1], 50.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	35.0 [1], 53.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	102.0 [1], 381.0 [2]
	(5Z)-5-[[1-(4-Bromophenyl)-2,5-dithiophen-2-ylpyrrol-3-yl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	754.0 [1], 1275.0 [2]
	(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione	IC50	54.0 [1], 391.0 [2]
	2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	160.0 [1], 1800.0 [2]
	2-Phenyl-N-[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	70.0 [1], 110.0 [2]
	2-Phenyl-N-[5-[4-[5-[(2-pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	70.0 [1], 83.0 [2]
	3-Hydroxy-N-[5-[4-[5-[(3-hydroxy-2-phenylpropanoyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylpropanamide	IC50	40.0 [1], 220.0 [2]
	(2S)-2-Hydroxy-N-[5-[4-[5-[[(2S)-2-hydroxy-2-phenylacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	140.0 [1], 380.0 [2]
	(2S)-2-Amino-N-[5-[4-[5-[[(2S)-2-amino-2-phenylacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	2800.0 [1], 3100.0 [2]
	Ethyl N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]carbamate	IC50	810.0 [1]
	Tert-butyl 4-[[3-[2-[[5-[2-[[5-[[2-[3-[[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]methyl]phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]methylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl]methyl]piperazine-1-carboxylate	IC50	150.0 [1], 2200.0 [2]
	2-(3-Bromophenyl)-N-[5-[4-[5-[[2-(3-bromophenyl)-2-hydroxyacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-hydroxyacetamide	IC50	40.0 [1], 670.0 [2]
	2-Phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]acetamide	IC50	10.0 [1], 57.0 [2]
	2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-oxadiazol-2-yl]butyl]-1,3,4-oxadiazol-2-yl]acetamide	IC50	20000.0 [1]
	2-(3-Chlorophenyl)-N-[5-[4-[5-[[2-(3-chlorophenyl)-2-hydroxyacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-hydroxyacetamide	IC50	31.0 [1], 520.0 [2]
	2-Hydroxy-2-(3-methoxyphenyl)-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	7.0 [1], 180.0 [2]
	2-(3-Chlorophenyl)-2-hydroxy-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	6.0 [1], 180.0 [2]
	2-[3-(Aminomethyl)phenyl]-N-[5-[4-[5-[[2-[3-(aminomethyl)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	170.0 [1], 660.0 [2]
	N-[6-[4-[5-[[2-[3-(Aminomethyl)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-phenylacetamide	IC50	13.0 [1], 130.0 [2]
	2-(3-Chlorophenyl)-2-hydroxy-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	24.0 [1], 130.0 [2]
	2-Hydroxy-2-phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]acetamide	IC50	30.0 [1], 150.0 [2]
	N-[5-[4-[6-[[2-[3-(Aminomethyl)phenyl]acetyl]amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	9.0 [1], 110.0 [2]
	Tert-butyl N-[[3-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamate	IC50	5.0 [1], 380.0 [2]
	Tert-butyl N-[[3-[2-oxo-2-[[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamate	IC50	5.0 [1], 160.0 [2]
	Ethyl N-[[3-[2-oxo-2-[[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamate	IC50	3.0 [1], 99.0 [2]
	Ethyl N-[[3-[2-oxo-2-[[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]amino]ethyl]phenyl]methyl]carbamate	IC50	3.0 [1], 81.0 [2]
	Tert-butyl N-[[3-[2-[[5-[4-[5-[[2-[3-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl]methyl]carbamate	IC50	11.0 [1], 4600.0 [2]
	2-(3-Bromophenyl)-N-[5-[2-[2-[5-[[2-(3-bromophenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	5000.0 [1], 7400.0 [2]
	N-[5-[4-[5-[[2-(4-Hydroxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	70.0 [1]
	N-[5-[4-[5-[[2-(4-Aminophenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	2300.0 [1]
	2-Phenyl-N-[5-[[(3R)-1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	30.0 [1]
	2-Phenyl-N-[5-[[(3S)-1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	70.0 [1]
	2-Phenyl-N-[5-[(3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	40.0 [1]
	2-Phenyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	30.0 [1]
	2-Phenyl-N-[6-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]oxypiperidin-1-yl]pyridazin-3-yl]acetamide	IC50	98.0 [1]
	N-[5-[1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	207.0 [1]
	2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	5000.0 [1]
	2-Phenyl-N-[5-[(3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	30.0 [1]
	2-Phenyl-N-[5-[(3R)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	36.0 [1]
	2-Phenyl-N-[6-[1-[6-[(2-phenylacetyl)amino]pyridin-3-yl]piperidin-4-yl]oxypyridin-3-yl]acetamide	IC50	5000.0 [1]
	2-Phenyl-N-[5-[3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]azetidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	60.0 [1]
	2-Cyclopropyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	30.0 [1]
	2-Phenyl-N-[5-[3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	490.0 [1]
	N-[5-[4-[(5-Acetamido-1,3,4-thiadiazol-2-yl)oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	1005.0 [1]
	N-[5-[(3S)-1-(5-Amino-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	9700.0 [1]
	N-[5-[(3R)-1-(5-Amino-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	1400.0 [1]
	2-Phenyl-N-[5-[(3R)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	790.0 [1]
	N-[5-[[1-(5-Amino-1,3,4-thiadiazol-2-yl)azetidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	227.0 [1]
	2-Phenyl-N-[5-[[1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperidin-4-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	29.0 [1]
	2-Phenyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	190.0 [1]
	2-Cyclopropyl-N-[5-[4-[[5-[(2-cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	157.0 [1]
	N-[5-[[(3S)-1-(5-Acetamido-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	7700.0 [1]
	2-Phenyl-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridin-3-yl]oxypiperidin-1-yl]pyridin-2-yl]acetamide	IC50	5000.0 [1]
	N-[5-[[(3R)-1-(5-Acetamido-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	720.0 [1]
	2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperazin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	3070.0 [1]
	2-Phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]pyridin-2-yl]oxypiperidin-1-yl]pyridin-3-yl]acetamide	IC50	5000.0 [1]
	2-Phenyl-N-[6-[1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperidin-4-yl]oxypyridazin-3-yl]acetamide	IC50	36.0 [1]
	N-[5-[1-(5-Amino-1,3,4-thiadiazol-2-yl)azetidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	540.0 [1]
	2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]pyrazin-2-yl]oxypiperidin-1-yl]pyrazin-2-yl]acetamide	IC50	5000.0 [1]
	2-Phenyl-N-[5-[[(1S,3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]cyclopentyl]amino]-1,3,4-thiadiazol-2-yl]acetamide	IC50	50.0 [1]
	2-Phenyl-N-[5-[4-[5-[[2-(4-phenylmethoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	25000.0 [1]
	N-[5-[4-[5-[[2-[4-(Dimethylamino)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	3000.0 [1]
	N-[5-[4-[5-[[2-(3-Hydroxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	120.0 [1]
	N-[5-[4-[5-[[2-(5-Bromopyridin-2-yl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	170.0 [1]
	[4-[2-Oxo-2-[[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetate	IC50	120.0 [1]
	2-(4-Hydroxyphenyl)-N-[5-[4-[5-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	510.0 [1]
	2-(4-Hydroxyphenyl)-N-[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	140.0 [1]
	N-[5-[4-[5-[[2-(4-Methoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	210.0 [1]
	N-[5-[4-[5-[[2-(4-Phenoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide	IC50	380.0 [1]
	4-[2-Oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoic acid	IC50	110.0 [1]
	[4-[2-[[5-[4-[5-[[2-(4-Acetyloxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl] acetate	IC50	1200.0 [1]
	[4-[2-Oxo-2-[[5-[4-[5-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetate	IC50	2000.0 [1]
	[4-[2-Oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetate	IC50	540.0 [1]
	Methyl 4-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoate	IC50	13000.0 [1]
	Tert-butyl N-[4-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]carbamate	IC50	450.0 [1]
	(3S,4S,6R)-6-[(1S)-1-[(1S,3R,8S,9S,10R,13S,14S,17R)-1,3-Dihydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-3,4-dihydroxy-3,4-dimethyloxan-2-one	IC50	100000.0 [1]
	(3S,4S,6R)-3,4-Dihydroxy-6-[(1S)-1-[(1S,3R,8S,9S,10R,13S,14S,17R)-1-hydroxy-10,13-dimethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-3,4-dimethyloxan-2-one	IC50	100000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Glutaminase kidney isoform, mitochondrial Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/glutaminase-kidney-isoform-mitochondrial-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Glutaminase kidney isoform, mitochondrial Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutaminase-kidney-isoform-mitochondrial-inhibitors-ic50-ki.
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