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Glycogen synthase kinase-3 alpha Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Pyrazolopyridazine 1aIC50250.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 13IC500.8 [1]
N-(5-Phenyl-2H-pyrazolo[3,4-b]pyridin-3-yl)butanamideIC5056.0 [1]
Pyrazolopyridazine 5IC504.0 [1]
Chir-99021IC507.8 [1], 10.0 [2]
3-(3-Chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dioneIC5078.0 [1], 104.0 [2]
4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenolIC50500.0 [1], 1500.0 [2]
N-[5-Bromo-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamideIC507.0 [1]
2-Chloro-5-[4-(3-chloro-phenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-ylamino]-benzoic acidIC5076.0 [1], 76000.0 [2]
N-[6-(3-Hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamideIC5012.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 12IC5024.0 [1]
Pyrazolo[3,4-b]pyridine analogue 9IC504.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 5IC508.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 14IC501.0 [1]
Pyrazolopyridine deriv. 13IC505.0 [1]
Pyrazolopyridine deriv. 18IC5018.0 [1]
Pyrazolopyridine deriv. 20IC507.0 [1]
(5-Bromo-6-phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl) cyclopropane carboxamideIC5075.0 [1]
CID 9957049IC500.65 [1], 27.1 [2]
2-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-fluorobenzonitrileIC502.0 [1], 230.0 [2]
3-(2,4-Dichlorophenyl)-4-(1-(111C)methylindol-3-yl)pyrrole-2,5-dioneIC5034.0 [1]
3-(2,4-Dichlorophenyl)-4-(1-(111C)methylindol-3-yl)pyrrole-2,5-dioneKi9.0 [1]
StaurosporineIC5028.0 [1]
HarmineIC5010000.0 [1]
3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dioneIC5034.0 [1]
6-Bromoindirubin-3'-oximeIC505.0 [1]
N-(4-Methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-YL)ureaIC5070000.0 [1]
AlsterpaulloneIC504.0 [1]
Manzamine AIC5025000.0 [1]
LY-2090314IC501.5 [1]
CID 53396311IC507.0 [1]
4-Methyl-5-(2-((4-morpholinophenyl)amino)-pyrimidin-4-yl)thiazol-2-amineKi10000.0 [1]
Aminofurazanyl-azabenzimidazole 6nIC501260.0 [1]
Leucettine L41IC50210.0 [1]
JNK Inhibitor VIIIKi8900.0 [1]
IlorasertibIC5010000.0 [1]
GSK-3 Inhibitor IIIC50390.0 [1]
8-(3-Chloro-5-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-oneIC50462.0 [1]
Pyridine, 4-[5-[(phenylmethyl)thio]-1,3,4-oxadiazol-2-yl]-IC502244.0 [1]
Leucettamine BIC507700.0 [1]
CID 59604787IC5010000.0 [1]
PalinurinIC501600.0 [1]
N-(6-Phenyl-1H-indazol-3-yl)cyclopropanecarboxamideIC50498.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 23IC501.0 [1]
2-(Phenylamino)-3-phenylmaleimideIC50529000.0 [1]
3-[(3-Chloro-4-Hydroxyphenyl)amino]-4-(3-Chlorophenyl)-1h-Pyrrole-2,5-DioneIC5094000.0 [1]
4-Arylmaleimide deriv. 6-lIC5020000.0 [1]
Pyrazolopyridazine deriv. 13IC509.0 [1]
N-[6-(Furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamideIC50141.0 [1]
N-[6-(3-Sulfamoylphenyl)-1H-indazol-3-yl]cyclopropanecarboxamideIC50481.0 [1]
Indazole analogue 12IC5015.0 [1]
4-[(5-Pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]benzonitrileIC507379.0 [1]
5-Phenyl-1H-pyrazolo[3,4-c]pyridazin-3-amineIC50530.0 [1]
4-Arylmaleimide deriv. 6cIC50216000.0 [1]
4-Arylmaleimide deriv. 6pIC50374000.0 [1]
4-Arylmaleimide deriv. 6-gIC5093000.0 [1]
4-Arylmaleimide deriv. 6ccIC50109000.0 [1]
4-Arylmaleimide deriv. 8fIC501412000.0 [1]
4-Arylmaleimide deriv. 8gIC50694000.0 [1]
N-[6-(4-Methoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamideIC505000.0 [1]
Indazole analogue 18IC501000.0 [1]
N-[6-(2,5-Difluorophenyl)-1H-indazol-3-yl]cyclopropanecarboxamideIC501000.0 [1]
Pyrazolo[3,4-b]pyridine analogue 37IC5018.0 [1]
5-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-amineIC50430.0 [1]
N-(5-Pyridin-3-yl-1H-pyrazolo[3,4-b]pyridin-3-yl)butyramideIC5011.0 [1]
N-[6-(4-Sulfamoylphenyl)-1H-indazol-3-yl]cyclopropanecarboxamideIC501000.0 [1]
Indazole analogue 17IC501000.0 [1]
N-[6-(4-Fluorophenyl)-1H-indazol-3-yl]cyclopropanecarboxamideIC501000.0 [1]
N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)acetamideKi8900.0 [1]
[(2s)-2-(4-Chlorophenyl)pyrrolidin-1-Yl](3-Methyl-1h-Pyrazolo[3,4-B]pyridin-5-Yl)methanoneIC50691.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 7IC508.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 10IC5036.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 15IC506.0 [1]
6-Aryl-pyrazolo[3,4-b]pyridine analogue 22IC5012.0 [1]
Pyrazolo[3,4-b]pyridine analogue 6IC505.0 [1]
4-Amino-5-chloro-6-ethoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamideKi8900.0 [1]
[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanoneIC509100.0 [1]
Cyclapolin 9IC50100000.0 [1]
7-Chloro-3-oxo-8-(1,3-thiazol-5-ylmethylamino)-11,16-dioxa-2,4,19,21-tetrazatricyclo[15.3.1.05,10]henicosa-1(20),5,7,9,17(21),18-hexaene-18-carbonitrileKi911.0 [1]
1-({4-[(3,4-Dichlorophenyl)methoxy]phenyl}methyl)azetidine-3-carboxylic acidIC5010000.0 [1]
N-(5-Phenyl-1H-pyrazolo[3,4-c]pyridin-3-yl)butanamideIC507.0 [1]
5-Phenyl-1H-pyrazolo[3,4-c]pyridin-3-amineIC501260.0 [1]
Pyrazolopyridine deriv. 9IC50291.0 [1]
Pyrazolopyridine deriv. 10IC5043.0 [1]
Pyrazolopyridine deriv. 12IC5019.0 [1]
1-Ethyl-3-(5-phenyl-2H-pyrazolo[3,4-b]pyridin-3-yl)ureaIC502810.0 [1]
Pyrazolopyridine deriv. 15IC503572.0 [1]
Pyrazolopyridine deriv. 17IC502345.0 [1]
Pyrazolopyridine deriv. 19IC5020.0 [1]
Pyrazolopyridine deriv. 21IC5027.0 [1]
Pyrazolopyridine deriv. 23IC50443.0 [1]
Pyrazolopyridine deriv. 24IC50851.0 [1]
Pyrazolopyridine deriv. 25IC50169.0 [1]
Pyrazolopyridine deriv. 26IC50241.0 [1]
N-(5-Phenyl-1H-indazol-3-yl)butanamideIC5099.0 [1]
Pyrazolopyrimidine deriv. 7IC502697.0 [1]
Pyrazolopyridazine deriv. 8IC50691.0 [1]
Pyrazolopyridazine deriv. 9IC5022.0 [1]
Pyrazolopyridazine deriv. 10IC5011.0 [1]
Pyrazolopyridazine deriv. 11IC507.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Glycogen synthase kinase-3 alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/glycogen-synthase-kinase-3-alpha-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Glycogen synthase kinase-3 alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glycogen-synthase-kinase-3-alpha-inhibitors-ic50-ki.
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