Growth factor receptor-bound protein 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-[[(2S)-1-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxo-3-[4-(phosphonomethyl)phenyl]propan-2-yl]amino]-2-oxoacetic acid	IC50	20.0 [1], 50.0 [2], 500.0 [3], 3000.0 [4]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	20.0 [1], 42.9 [2], 55.0 [3], 80.0 [4], 500.0 [5]
	2-[(9S,10S,11E,14R,18S)-18-(2-Amino-2-oxoethyl)-14-[(5-methylindol-1-yl)methyl]-8,17,20-trioxo-10-[4-(phosphonomethyl)phenyl]-7,16,19-triazaspiro[5.14]icos-11-en-9-yl]acetic acid	IC50	10.0 [1], 15.0 [2], 630.0 [3], 10000.0 [4]
	2-[4-[(2S)-3-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-2-(oxaloamino)-3-oxopropyl]phenyl]propanedioic acid	IC50	22.1 [1], 70.0 [2]
	2-[[(2S)-1-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-[4-(carboxymethyl)phenyl]-1-oxopropan-2-yl]amino]-2-oxoacetic acid	IC50	600.0 [1], 1000.0 [2]
	3-[(5S,8S,11S,14S,17S,20S,26S,29S,32R)-17-(2-Amino-2-oxoethyl)-32-carbamoyl-14-(2-carboxyethyl)-11,29-bis[(4-hydroxyphenyl)methyl]-8-(2-methylpropyl)-26-(2-methylsulfanylethyl)-3,6,9,12,15,18,21,24,27,30-decaoxo-20-propan-2-yl-1-thia-4,7,10,13,16,19,22,25,28,31-decazacyclotritriacont-5-yl]propanoic acid	IC50	15000.0 [1], 20000.0 [2], 100000.0 [3], 100000000.0 [4]
	[4-[(10R,11E,14S,18S)-18-(2-Amino-2-oxoethyl)-14-(naphthalen-1-ylmethyl)-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]phenyl]methylphosphonic acid	IC50	20.0 [1], 26.0 [2], 10000.0 [3]
	(3-Aminophenyl)methyl N-[(2S)-1-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	1.0 [1], 120.0 [2]
	2-[(9S,10S,11E,14S,18S)-18-(2-Amino-2-oxoethyl)-14-(naphthalen-1-ylmethyl)-8,17,20-trioxo-10-[4-(phosphonomethyl)phenyl]-7,16,19-triazaspiro[5.14]icos-11-en-9-yl]acetic acid	IC50	2.0 [1], 12.1 [2], 1000.0 [3]
	5-[(2S)-3-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-2-(oxaloamino)-3-oxopropyl]-2-(carboxymethoxy)benzoic acid	IC50	500.0 [1], 1300.0 [2]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(5-methylindol-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	0.4 [1], 4.0 [2]
	(3-Aminophenyl)methyl N-[(2S)-1-[[(2S,3S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	65.0 [1]
	2-[4-[(2S)-3-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-2-(oxaloamino)-3-oxopropyl]phenyl]-2-fluoropropanedioic acid	IC50	170.0 [1]
	2-[4-[(2S)-3-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-2-(oxaloamino)-3-oxopropyl]phenoxy]propanedioic acid	IC50	1100.0 [1]
	[4-[(2S)-2-Acetamido-3-[[(2S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	4320.0 [1]
	[4-[(2S)-2-Acetamido-3-[[2-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-2-oxoethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	67000.0 [1]
	2-[[(2S)-1-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-[4-(carboxymethoxy)phenyl]-1-oxopropan-2-yl]amino]-2-oxoacetic acid	IC50	15000.0 [1], 19000.0 [2]
	1,2,4-Oxadiazole Analogue 12d	IC50	500000.0 [1]
	2-[4-[(2S)-3-[[1-[[(2S)-4-Amino-1-[3-(5-methylindol-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-2-(oxaloamino)-3-oxopropyl]phenyl]propanedioic acid	IC50	8.0 [1]
	(3R)-4-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-4-oxo-3-[[4-(phosphonomethyl)phenyl]methyl]butanoic acid	IC50	8.0 [1], 10000.0 [2]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	47.0 [1], 70.0 [2]
	[[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]-difluoromethyl]phosphonic acid	IC50	80.0 [1], 500.0 [2]
	Disodium;2-[4-[(9S,10S,11E,14S,18S)-18-(2-amino-2-oxoethyl)-9-(carboxymethyl)-14-(naphthalen-1-ylmethyl)-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]phenyl]propanedioate	IC50	4.3 [1], 12.1 [2]
	[4-[(2S)-3-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-2-azido-3-oxopropyl]phenyl]methylphosphonic acid	IC50	5000.0 [1], 30000.0 [2]
	2-[[10-Amino-11-(4-diacetyloxyphosphoryloxyphenyl)-7,9-dioxoundecyl]amino]-4-(3-naphthalen-1-ylpropylamino)-4-oxobutanoic acid	IC50	47.0 [1], 64.0 [2]
	(2S)-2-[[(2S,3S)-2-[[(2S)-2-Amino-3-(4-diacetyloxyphosphoryloxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-(3-naphthalen-1-ylpropylamino)-4-oxobutanoic acid	IC50	330.0 [1], 580.0 [2]
	[2-Amino-4-[(2S)-2-amino-3-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	0.0 [1], 1.0 [2]
	Dactinomycin	IC50	5000.0 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(2-hydroxynaphthalen-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	43.0 [1]
	Actinomycin C3	IC50	7600.0 [1]
	8-O-Methylsclerotiorinamine	IC50	5300.0 [1]
	1,2,4-Oxadiazole Analogue 4a	IC50	456000.0 [1]
	1,2,4-Oxadiazole Analogue 5d	IC50	500000.0 [1]
	1,2,4-Oxadiazole Analogue 12b	IC50	500000.0 [1]
	1,2,4-Oxadiazole Analogue 5f	IC50	500000.0 [1]
	[4-[(2S)-2-Acetamido-3-[[(1S)-4-amino-1-[3-(carbamoylamino)phenyl]-4-oxobutyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	6500.0 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(8-hydroxynaphthalen-2-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	11.1 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(5-hydroxyindol-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	0.3 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(1R,2S)-2-carbamoylcyclohexyl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methyl-[hydroxy(phenyl)methyl]phosphinic acid	IC50	530.0 [1]
	[4-[2-(4-Aminopyrimidin-2-yl)-5-methyl-1,3-thiazol-4-yl]phenyl] dihydrogen phosphate	IC50	25900.0 [1]
	[4-[(2S)-2-Acetamido-3-[[(1S)-1-[3-(carbamoylamino)phenyl]-2-methylpropyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	6190.0 [1]
	[4-[(10S,14R,18S)-18-(2-Amino-2-oxoethyl)-14-(naphthalen-1-ylmethyl)-8,12,17,20-tetraoxo-7,11,16,19-tetrazaspiro[5.14]icosan-10-yl]phenyl]methylphosphonic acid	IC50	7900.0 [1]
	(4S)-4-Amino-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]amino]-5-oxopentanoic acid	IC50	7900.0 [1]
	(3-Aminophenyl)methyl N-[(2S)-1-[[(2S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	497.0 [1]
	(4S)-4-[(2-Aminobenzoyl)amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]amino]-5-oxopentanoic acid	IC50	22.0 [1]
	[4-[(2S)-2-Amino-3-[[(2S,3S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	56900.0 [1]
	Benzyl N-[(2S)-1-[[(2S,3S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	6350.0 [1]
	2-[4-[(2S)-2-[[(2S)-2-[(3-Aminophenyl)methoxycarbonylamino]-3-(4-phosphonooxyphenyl)propanoyl]amino]-3-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-2-methyl-3-oxopropyl]phenyl]acetic acid	IC50	198.0 [1]
	(2S)-2-[[1-[[(2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]amino]cyclohexanecarbonyl]amino]-N-(3-naphthalen-1-ylpropyl)butanediamide	IC50	50000.0 [1]
	[4-[(2S)-3-[[(2S)-1-[[(2S)-4-Amino-1-[[(2S)-1-[(2S)-2-(butylcarbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-oxo-2-(propanoylamino)propyl]phenyl] dihydrogen phosphate	IC50	1630.0 [1]
	4-[(2S)-2-[[(2S)-2-[(3-Aminophenyl)methoxycarbonylamino]-3-(4-phosphonooxyphenyl)propanoyl]amino]-3-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-2-methyl-3-oxopropyl]benzoic acid	IC50	153.0 [1]
	(3-Aminophenyl)methyl N-[(2S)-1-[[(2S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	235.0 [1]
	(3-Aminophenyl)methyl N-[(2S)-1-[[(2S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-2-methyl-1-oxopropan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	1098.0 [1]
	5-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]-2-(carboxymethoxy)benzoic acid	IC50	6700.0 [1]
	2-[4-[(2S)-2-[[(2S)-2-Acetamido-4-amino-4-oxobutanoyl]amino]-3-[[(2S)-1-[[(2S)-4-amino-1-[[(2S,3S)-1-[[(2S)-1-amino-4-carboxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-oxopropyl]phenoxy]propanedioic acid	IC50	120000.0 [1]
	[4-[(2S)-2-Acetamido-3-[[(2S,3S)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	IC50	8640.0 [1]
	2-[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]-2-(carboxymethoxy)phenoxy]acetic acid	IC50	100000.0 [1]
	2-[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenoxy]propanedioic acid	IC50	2750.0 [1]
	[4-[3-[[1-[[(2S)-1,4-Diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	52500.0 [1]
	[4-[(10S,12E,15S,19S)-19-(2-Amino-2-oxoethyl)-15-(naphthalen-1-ylmethyl)-8,18,21-trioxo-7,17,20-triazaspiro[5.15]henicos-12-en-10-yl]phenyl]methylphosphonic acid	IC50	10000.0 [1]
	(3R)-4-[[1-[[(2S)-4-Amino-1-[2-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]ethylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-4-oxo-3-[[4-(phosphonomethyl)phenyl]methyl]butanoic acid	IC50	167.0 [1]
	2-[(9S,10S,11E,14R,18S)-18-(2-Amino-2-oxoethyl)-10-[4-[[hydroxy(methyl)phosphoryl]methyl]phenyl]-14-[(5-methylindol-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-9-yl]acetic acid	IC50	6.3 [1]
	2-[4-[(9S,10S,11E,14R,18S)-18-(2-Amino-2-oxoethyl)-9-(carboxymethyl)-14-[(5-methylindol-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]anilino]-2-oxoacetic acid	IC50	8.8 [1]
	2-[4-[(9S,10S,11E,14R,18S)-18-(2-Amino-2-oxoethyl)-9-(carboxymethyl)-14-[(5-methylindol-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-10-yl]phenyl]propanedioic acid	IC50	3.3 [1]
	2-[(9S,10S,11E,14R,18S)-18-(2-Amino-2-oxoethyl)-10-[4-[[benzyl(hydroxy)phosphoryl]methyl]phenyl]-14-[(5-methylindol-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-9-yl]acetic acid	IC50	8.4 [1]
	2-[(9S,10S,11E,14R,18S)-18-(2-Amino-2-oxoethyl)-10-[4-(carboxymethyl)phenyl]-14-[(5-methylindol-1-yl)methyl]-8,17,20-trioxo-7,16,19-triazaspiro[5.14]icos-11-en-9-yl]acetic acid	IC50	22.5 [1]
	2-[[(9S,12S,15S,21R,30S)-9-[(3-Amino-4-hydroxyphenyl)methyl]-30-(2-amino-2-oxoethyl)-21-carbamoyl-12-(2-methylpropyl)-8,11,14,17,19,23,29,32-octaoxo-19lambda4-thia-7,10,13,16,22,28,31-heptazaspiro[5.26]dotriacontan-15-yl]methyl]propanedioic acid	IC50	58.0 [1]
	4-[(9S,12S,15S,19S,21R,30S)-30-(2-Amino-2-oxoethyl)-21-carbamoyl-9-[(4-hydroxyphenyl)methyl]-12-(2-methylpropyl)-8,11,14,17,19,23,29,32-octaoxo-19lambda4-thia-7,10,13,16,22,28,31-heptazaspiro[5.26]dotriacontan-15-yl]butanoic acid	IC50	77000.0 [1]
	2-[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]-2-fluoropropanedioic acid	IC50	680.0 [1]
	(3-Aminophenyl)methyl N-[(2S)-1-[[(2R)-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-1-oxo-2-(4-phosphonooxyphenyl)propan-2-yl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	13.0 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(1R,2S)-2-carbamoylcyclohexyl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methyl-(hydroxymethyl)phosphinic acid	IC50	7600.0 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(1R,2S)-2-carbamoylcyclohexyl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methyl-(2-hydroxyethyl)phosphinic acid	IC50	1600.0 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(1R,2S)-2-carbamoylcyclohexyl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methyl-benzylphosphinic acid	IC50	1200.0 [1]
	[4-[3-[[1-[[(2S)-4-Amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	2000.0 [1]
	(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-(4-Carbamimidoylcyclohexyl)-2-[[(2S)-1-[(2S)-2-[[6-(carbamothioylamino)-3',6'-dihydroxyspiro[1H-2-benzofuran-3,9'-xanthene]-1-carbonyl]amino]-2-piperidin-4-ylacetyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3,3-dimethylbutanoyl]amino]-4-methylpentanoic acid	IC50	700.0 [1]
	Phosphoric acid 4-[2-(4-amino-2-pyrimidinylamino)ethyl]phenyl ester	IC50	200000.0 [1]
	1-[3-[4-(3-Aminophenyl)butyl]phenyl]-6,6-dimethyl-1,3,5-triazine-2,4-diamine;hydrochloride	IC50	5700000.0 [1]
	4-[(5S,8S,11S,14S,17S,26R)-17-(2-Amino-2-oxoethyl)-26-carbamoyl-14-(3-carboxypropyl)-11-[(4-hydroxyphenyl)methyl]-14-methyl-8-(2-methylpropyl)-3,6,9,12,15,18,24-heptaoxo-1-thia-4,7,10,13,16,19,25-heptazacycloheptacos-5-yl]butanoic acid	IC50	60700.0 [1]
	4-[(5S,8S,11S,14R,17S,26R)-17-(2-Amino-2-oxoethyl)-26-carbamoyl-14-(2-carboxyethyl)-11-[(4-hydroxyphenyl)methyl]-14-methyl-8-(2-methylpropyl)-3,6,9,12,15,18,24-heptaoxo-1-thia-4,7,10,13,16,19,25-heptazacycloheptacos-5-yl]butanoic acid	IC50	60500.0 [1]
	4-[(5S,8S,11S,14S,17S,26R)-11-[(3-Amino-4-hydroxyphenyl)methyl]-17-(2-amino-2-oxoethyl)-26-carbamoyl-14-(2-carboxyethyl)-14-methyl-8-(2-methylpropyl)-3,6,9,12,15,18,24-heptaoxo-1-thia-4,7,10,13,16,19,25-heptazacycloheptacos-5-yl]butanoic acid	IC50	17000.0 [1]
	4-[(5S,8S,11S,14S,17S,26R)-17-(2-Amino-2-oxoethyl)-26-carbamoyl-14-(2-carboxyethyl)-11-[(4-hydroxyphenyl)methyl]-14-methyl-8-(2-methylpropyl)-3,6,9,12,15,18,24-heptaoxo-1-thia-4,7,10,13,16,19,25-heptazacycloheptacos-5-yl]butanoic acid	IC50	70000.0 [1]
	2-[[(5S,8S,11S,14S,17S,26R)-11-[(3-Amino-4-hydroxyphenyl)methyl]-17-(2-amino-2-oxoethyl)-26-carbamoyl-14-(3-carboxypropyl)-14-methyl-8-(2-methylpropyl)-3,6,9,12,15,18,24-heptaoxo-1-thia-4,7,10,13,16,19,25-heptazacycloheptacos-5-yl]methyl]propanedioic acid	IC50	9500.0 [1]
	(4S)-4-[[(2S)-3-[3-(2-Carboxyethyl)-4-hydroxyphenyl]-2-[[(2S)-2-[[(2S)-5-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-5-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-4-methyl-5-oxopentanoic acid	IC50	5600.0 [1]
	(4S)-4-[[(2S)-3-[3-(2-Carboxyethyl)-4-hydroxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoyl]amino]-5-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-4-methyl-5-oxopentanoic acid	IC50	168000.0 [1]
	(5S)-6-[[(2S)-1-[[(2S)-3-(3-Amino-4-hydroxyphenyl)-1-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(9H-fluoren-9-ylmethoxycarbonylamino)-6-oxohexanoic acid	IC50	5800.0 [1]
	2-[(2S)-2-Amino-3-[[(2S)-1-[[(2S)-3-(3-amino-4-hydroxyphenyl)-1-[[(2S)-4-carboxy-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-2-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-oxopropyl]propanedioic acid	IC50	19000.0 [1]
	(5R)-6-[[(2S)-1-[[(2S)-1-[[1-[[(2S)-1,4-Diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(9H-fluoren-9-ylmethoxycarbonylamino)-5-methyl-6-oxohexanoic acid	IC50	1000000.0 [1]
	(5R)-6-[[(2S)-1-[[(2S)-3-(3-Amino-4-hydroxyphenyl)-1-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(9H-fluoren-9-ylmethoxycarbonylamino)-5-methyl-6-oxohexanoic acid	IC50	700000.0 [1]
	2-[(2S)-3-[[(2S)-1-[[(2S)-3-(3-Amino-4-hydroxyphenyl)-1-[[(2S)-4-carboxy-1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]amino]-2-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-oxopropyl]propanedioic acid	IC50	4400.0 [1]
	2-[(2S)-3-[[(2S)-1-[[(2S)-3-(3-Amino-4-hydroxyphenyl)-1-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-oxopropyl]propanedioic acid	IC50	2500.0 [1]
	(5S)-6-[[(2S)-1-[[(2S)-3-(3-Amino-4-hydroxyphenyl)-1-[[1-[[(2S)-1,4-diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(9H-fluoren-9-ylmethoxycarbonylamino)-5-methyl-6-oxohexanoic acid	IC50	3900.0 [1]
	(5S)-6-[[(2S)-1-[[(2S)-1-[[1-[[(2S)-1,4-Diamino-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(9H-fluoren-9-ylmethoxycarbonylamino)-5-methyl-6-oxohexanoic acid	IC50	117700.0 [1]
	4-[(5S,8S,11S,14S,17S,26R)-17-(2-Amino-2-oxoethyl)-26-carbamoyl-14-(carboxymethyl)-11-[(4-hydroxyphenyl)methyl]-14-methyl-8-(2-methylpropyl)-3,6,9,12,15,18,24-heptaoxo-1-thia-4,7,10,13,16,19,25-heptazacycloheptacos-5-yl]butanoic acid	IC50	108000.0 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(6,7-dimethoxynaphthalen-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	84.4 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(6-methoxynaphthalen-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	129.9 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(6-hydroxynaphthalen-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	42.7 [1]
	[4-[(2S)-2-Acetamido-3-[[1-[[(2S)-4-amino-1-[3-(7-hydroxynaphthalen-1-yl)propylamino]-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-3-oxopropyl]phenyl]methylphosphonic acid	IC50	24.6 [1]
	2-[4-[(2S)-3-[[1-[[(2S)-4-Amino-1-(3-naphthalen-2-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-2-(oxaloamino)-3-oxopropyl]phenyl]propanedioic acid	IC50	50.0 [1]
	(3-Aminophenyl)methyl N-[(2S)-1-[[1-[[(6S)-6-carbamoylcyclohex-2-en-1-yl]carbamoyl]cyclohexyl]amino]-1-oxo-3-(4-phosphonooxyphenyl)propan-2-yl]carbamate	IC50	1.6 [1]
	2-[[(5S,8R,11S,14R,17S,20R,26R,29S,32R)-17-(2-Amino-2-oxoethyl)-32-carbamoyl-14-(3-carboxypropyl)-11,29-bis[(4-hydroxyphenyl)methyl]-8-(2-methylpropyl)-26-(2-methylsulfanylethyl)-3,6,9,12,15,18,21,24,27,30-decaoxo-20-propan-2-yl-1-thia-4,7,10,13,16,19,22,25,28,31-decazacyclotritriacont-5-yl]methyl]propanedioic acid	IC50	1510.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Growth factor receptor-bound protein 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/growth-factor-receptor-bound-protein-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Growth factor receptor-bound protein 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/growth-factor-receptor-bound-protein-2-inhibitors-ic50-ki.
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