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Heat shock factor protein 1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]-2-(2-pyrrolidin-1-ylethoxy)quinoline-6-carboxamideIC5019.0 [1], 40.0 [2]
N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamideIC502.82 [1], 68.0 [2]
6-Imidazo[4,5-b]pyridin-1-yl-N-[5-(2-piperidin-1-ylethoxy)pyridin-2-yl]pyrimidin-4-amineIC5015.0 [1]
QuercetinIC5050000.0 [1]
VemurafenibIC5010000.0 [1]
DabrafenibIC5010000.0 [1]
DinaciclibIC507.0 [1]
3-(Dimethylamino)-N-(3-(4-hydroxybenzamido)-4-methylphenyl)benzamideIC5010000.0 [1]
Raf265(chir-265)IC5010000.0 [1]
(E)-5-(1-(2-Hydroxyethyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oximeIC5010000.0 [1]
CID 46209401IC5010000.0 [1]
AZ-628IC5010000.0 [1]
Kribb11IC501200.0 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]-2-[2-(propanoylamino)ethoxy]quinoline-6-carboxamideIC50120.0 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]-1,2,3,4-tetrahydroquinoline-6-carboxamideIC50220.0 [1]
2-(2-Aminoethoxy)-N-[5-(2,3-dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]quinoline-6-carboxamideIC5026.3 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]isoquinoline-7-carboxamideIC5051.0 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2-methylphenyl]quinoline-6-carboxamideIC5012.0 [1]
N-[5-(3,4-Dihydro-2H-chromene-7-carbonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamideIC50450.0 [1]
N-[5-[(3,4-Dimethoxybenzoyl)amino]-2-methylphenyl]-2-methylquinoline-6-carboxamideIC5010000.0 [1]
N-[5-(3,4-Dihydro-1H-isochromene-7-carbonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamideIC5010000.0 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamideIC5010000.0 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxine-5-carbonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamideIC5010000.0 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2,4-dimethylphenyl]-2-methylquinoline-6-carboxamideIC5010000.0 [1]
N-[5-[2,3-Dihydro-1,4-benzodioxine-6-carbonyl(methyl)amino]-2-methylphenyl]-2-methylquinoline-6-carboxamideIC5010000.0 [1]
N-[5-(2,3-Dihydro-1,4-benzodioxine-5-carbonylamino)-2-methylphenyl]-2-(2-pyrrolidin-1-ylethoxy)quinoline-6-carboxamideIC5010000.0 [1]
N-[3-(2,3-Dihydro-1,4-benzodioxine-6-carbonylamino)-2,6-dimethylphenyl]-2-methylquinoline-6-carboxamideIC5010000.0 [1]
N-[5-(3,4-Dihydro-2H-chromene-6-carbonylamino)-2-methylphenyl]-2-methylquinoline-6-carboxamideIC502600.0 [1]
6-Imidazo[4,5-b]pyridin-1-yl-N-[5-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridin-2-yl]pyrimidin-4-amineIC5014.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-imidazo[4,5-b]pyridin-1-ylpyrimidin-4-amineIC5028.0 [1]
6-(Benzimidazol-1-yl)-N-[5-[3-(dimethylamino)propyl]pyridin-2-yl]pyrimidin-4-amineIC50198.0 [1]
6-(Benzimidazol-1-yl)-N-[5-(2-morpholin-4-ylethoxy)pyridin-2-yl]pyrimidin-4-amineIC50295.0 [1]
2-[4-[[6-(Benzimidazol-1-yl)pyrimidin-4-yl]amino]phenyl]ethanolIC502000.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-indol-1-ylpyrimidin-4-amineIC502330.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-imidazol-1-ylpyrimidin-4-amineIC506150.0 [1]
6-(Benzimidazol-1-yl)-N-[5-(4-methylpiperazin-1-yl)pyridin-2-yl]pyrimidin-4-amineIC50450.0 [1]
6-(Benzimidazol-1-yl)-N-[5-(2-piperidin-1-ylethoxy)pyridin-2-yl]pyrimidin-4-amineIC5057.0 [1]
6-(Benzimidazol-1-yl)-N-[4-[2-(dimethylamino)ethoxy]phenyl]pyrimidin-4-amineIC501350.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-(2-methylbenzimidazol-1-yl)pyrimidin-4-amineIC504280.0 [1]
6-(Benzimidazol-1-yl)-N-[5-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridin-2-yl]pyrimidin-4-amineIC5055.0 [1]
6-(Benzimidazol-1-yl)-N-[5-(1-methylpiperidin-4-yl)oxypyridin-2-yl]pyrimidin-4-amineIC50884.0 [1]
6-(Benzimidazol-1-yl)-N-pyridin-2-ylpyrimidin-4-amineIC50842.0 [1]
6-(Benzimidazol-1-yl)-N-[5-[(2S)-2,4-dimethylpiperazin-1-yl]pyridin-2-yl]pyrimidin-4-amineIC501380.0 [1]
6-(Benzimidazol-1-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-4-amineIC50610.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-imidazo[4,5-b]pyridin-3-ylpyrimidin-4-amineIC50760.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-(6-methylbenzimidazol-1-yl)pyrimidin-4-amineIC5039.0 [1]
N-[5-[(5-Tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperazine-1-carboxamideIC50750.0 [1]
6-(Benzimidazol-1-yl)-N-[5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]pyridin-2-yl]pyrimidin-4-amineIC5045.0 [1]
6-(Benzimidazol-1-yl)-N-[5-[2-(dimethylamino)ethoxy]pyridin-2-yl]-5-methylpyrimidin-4-amineIC5030000.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-indazol-1-ylpyrimidin-4-amineIC5030000.0 [1]
N-[5-[2-(Dimethylamino)ethoxy]pyridin-2-yl]-6-quinolin-3-ylpyrimidin-4-amineIC5017600.0 [1]
6-(Benzimidazol-1-yl)-N-[5-[2-(dimethylamino)ethoxy]pyridin-2-yl]pyrimidin-4-amineIC5080.0 [1]
6-(Benzimidazol-1-Yl)-N-[5-[3-(Dimethylamino)propoxy]pyridin-2-Yl]pyrimidin-4-AmineIC50165.0 [1]
Items per page: 1 - 10 of 53
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References

This online tool may be cited as follows

MLA

"Quest Database™ Heat shock factor protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/heat-shock-factor-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Heat shock factor protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/heat-shock-factor-protein-1-inhibitors-ic50-ki.
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