Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 25262525	IC50	8100.0 [1]
	CID 25262525	Ki	2900.0 [1], 33870.0 [2]
	Lyp-IN-1	IC50	250.0 [1], 259.0 [2]
	Lyp-IN-1	Ki	110.0 [1]
	3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-carbostyril	IC50	13700.0 [1], 20600.0 [2]
	3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-carbostyril	Ki	12480.0 [1], 38060.0 [2]
	3-[2-(3-Chlorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acid	IC50	990.0 [1], 1000.0 [2]
	3-[[Benzyl-[(4-chlorophenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	IC50	9190.0 [1]
	3-[[Benzyl-[(4-chlorophenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	Ki	8070.0 [1], 23890.0 [2]
	3-[(4-Benzhydrylpiperazin-1-yl)-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	IC50	6310.0 [1]
	3-[(4-Benzhydrylpiperazin-1-yl)-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	Ki	11040.0 [1], 21310.0 [2]
	3-[[Benzyl-[(4-propan-2-ylphenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	IC50	5280.0 [1]
	3-[[Benzyl-[(4-propan-2-ylphenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	Ki	2160.0 [1], 10650.0 [2]
	3-[2-Azaspiro[5.5]undecan-2-yl-[1-(oxolan-2-yl)tetrazol-5-yl]methyl]-6-methyl-1H-quinolin-2-one	IC50	5580.0 [1]
	3-[2-Azaspiro[5.5]undecan-2-yl-[1-(oxolan-2-yl)tetrazol-5-yl]methyl]-6-methyl-1H-quinolin-2-one	Ki	3070.0 [1], 17620.0 [2]
	6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acid	IC50	2000.0 [1]
	3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acid	IC50	1300.0 [1]
	6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acid	IC50	2000.0 [1]
	6-Hydroxy-2-phenyl-3-(2-phenylethynyl)benzofuran-5-carboxylic acid	IC50	4900.0 [1]
	3-[2-(3-Fluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acid	IC50	3900.0 [1]
	6-Hydroxy-3-[2-(3-methoxyphenyl)ethynyl]-2-phenyl-benzofuran-5-carboxylic acid	IC50	17000.0 [1]
	3-[2-(2,4-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid	IC50	3500.0 [1]
	6-Hydroxy-3-[2-(4-phenoxyphenyl)ethynyl]-2-phenyl-benzofuran-5-carboxylic acid	IC50	630.0 [1]
	3-Ethynyl-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acid	IC50	50000.0 [1]
	4-[[4-[(E)-[5-[4-(Dimethylamino)phenyl]-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]methyl]benzoic acid	IC50	6100.0 [1]
	4-[[4-[(E)-[5-[4-(Dimethylamino)phenyl]-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]methyl]benzoic acid	Ki	2870.0 [1]
	CID 1435211	IC50	9900.0 [1], 22000.0 [2]
	2-(3-Cyano-5,8-dimethylquinolin-2-yl)sulfanyl-N-(2-ethyl-6-methylphenyl)acetamide	IC50	5400.0 [1], 11300.0 [2]
	2-[1-(4-Methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanyl-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone	IC50	22000.0 [1], 80000.0 [2]
	2-[(5,6-Dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide	IC50	6200.0 [1], 11200.0 [2]
	2-[[6-(1,3-Dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]-N-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]acetamide	IC50	18500.0 [1]
	2-[[6-(1,3-Dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]-N-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]acetamide	Ki	9970.0 [1]
	4-[3-(4-Methoxyphenyl)-3-oxopropyl]-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]benzamide	IC50	10000.0 [1], 40000.0 [2]
	3-Ethynyl-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid	IC50	4200.0 [1]
	3-[2-(3-Chlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid	IC50	680.0 [1]
	3-[2-(3-Chlorophenyl)ethynyl]-6-hydroxy-2-[3-[2-oxo-2-(4-propan-2-ylanilino)ethoxy]phenyl]-1-benzofuran-5-carboxylic acid	IC50	300.0 [1]
	2-Hydroxy-1,4-naphthoquinone	IC50	5600.0 [1]
	1,2-Naphthoquinone	IC50	1100.0 [1]
	Naphthalene-1,2-diol	IC50	2520.0 [1]
	Oxyresveratrol	IC50	31450.0 [1]
	Morusin	IC50	14970.0 [1]
	Norartocarpetin	IC50	30290.0 [1]
	Cudraflavanone A	IC50	9540.0 [1]
	Cefsulodin sodium salt	IC50	200000.0 [1]
	6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acid	IC50	25000.0 [1]
	CID 6393068	IC50	1900.0 [1]
	CID 11839289	IC50	4800.0 [1]
	CID 11839290	IC50	1000.0 [1]
	CID 11839291	IC50	1900.0 [1]
	CID 2012945	IC50	1300.0 [1]
	2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid	IC50	2500.0 [1]
	CID 71734765	IC50	171.0 [1]
	CID 2030970	IC50	980.0 [1]
	2-[4-[(E)-[5-(3-Methoxyphenyl)-7-methyl-3-oxo-6-(phenylcarbamoyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acid	IC50	79500.0 [1]
	3-[(1-Cyclopentyltetrazol-5-yl)-[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-6-methyl-1H-quinolin-2-one	IC50	40000.0 [1]
	2-[6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-benzothiazol-2-ylsulfanyl]-N,N-dimethyl-acetamide	IC50	100000.0 [1]
	5,7-Dichloro-4-((3-(4-methoxyphenylthio)benzyl)(methyl)amino)quinoline-2-carboxylic acid	Ki	5530.0 [1]
	3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-8-methyl-1H-quinolin-2-one	IC50	15750.0 [1]
	[(1R,2S,6S)-2-[2,6-Dihydroxy-4-(6-hydroxy-1-benzofuran-2-yl)phenyl]-6-(2,4-dihydroxyphenyl)-4-methylcyclohex-3-en-1-yl]-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]methanone	IC50	7290.0 [1]
	2-Methyl-3-[5-[(Z)-[3-[2-(4-methylanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoic acid	IC50	3300.0 [1]
	N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide	IC50	50000.0 [1]
	2-(1,3-Benzothiazol-2-ylsulfanyl)-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide	IC50	100000.0 [1]
	2-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]phenoxy]acetic acid	Ki	200000.0 [1]
	2-(5-Methylfuran-2-yl)-N-[[3-[[[2-(5-methylfuran-2-yl)quinoline-4-carbonyl]amino]methyl]phenyl]methyl]quinoline-4-carboxamide	Ki	17860.0 [1]
	5-[(2S)-2-Acetamido-3-[4-(3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxopropyl]-2-(carboxymethoxy)benzoic acid	Ki	129100.0 [1]
	1,1,1,3,3,3-Hexafluoro-2-phenylpropan-2-ol	IC50	500000.0 [1]
	3-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]-N-oxaloanilino]-2-methylpropanoic acid	Ki	16700.0 [1]
	5-(4-Bromophenyl)-N-(2-pyridin-3-yl-1,3-benzoxazol-5-yl)furan-2-carboxamide	Ki	14860.0 [1]
	3-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]-N-oxaloanilino]pentanoic acid	Ki	9300.0 [1]
	5-[5-[(Z)-[3-(Carboxymethyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]-2-hydroxybenzoic acid	IC50	8700.0 [1]
	2-(1-Carboxyethoxy)-5-[(2S)-3-[4-(3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-3-oxopropyl]benzoic acid	Ki	1970.0 [1]
	3-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]-N-oxaloanilino]-2-phenylpropanoic acid	Ki	97800.0 [1]
	3-Chloro-N-(5-methyl-1,3-benzothiazol-2-yl)-1-benzothiophene-2-carboxamide	IC50	29500.0 [1]
	2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	Kuwanon-G	IC50	18530.0 [1]
	(2S)-2-[3-[(1R,5S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one	IC50	12120.0 [1]
	5-[5-[(E)-[3-(Carboxymethyl)-2,4-dioxoimidazolidin-1-yl]iminomethyl]furan-2-yl]-2-hydroxybenzoic acid	IC50	36000.0 [1]
	5-[5-[(E)-[3-(Carboxymethyl)-2,4-dioxoimidazolidin-1-yl]iminomethyl]thiophen-2-yl]-2-hydroxybenzoic acid	IC50	44000.0 [1]
	Methyl 5-[5-[(E)-(2,4-dioxoimidazolidin-1-yl)iminomethyl]thiophen-2-yl]-2-hydroxybenzoate	IC50	44000.0 [1]
	5-[5-[(E)-(2,4-Dioxoimidazolidin-1-yl)iminomethyl]thiophen-2-yl]-2-hydroxybenzoic acid	IC50	34000.0 [1]
	Methyl 5-[5-[(E)-(2,4-dioxoimidazolidin-1-yl)iminomethyl]furan-2-yl]-2-hydroxybenzoate	IC50	44000.0 [1]
	5-[5-[(E)-(2,4-Dioxoimidazolidin-1-yl)iminomethyl]furan-2-yl]-2-hydroxybenzoic acid	IC50	44000.0 [1]
	2-(3-Cyano-7-methoxyquinolin-2-yl)sulfanyl-N-(2,3-dimethylphenyl)acetamide	IC50	30500.0 [1]
	1-[(E)-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]methylideneamino]-3-(4-methylphenyl)thiourea	IC50	50000.0 [1]
	1-Naphthalen-1-yl-3-[(E)-(4-phenylphenyl)methylideneamino]thiourea	IC50	50000.0 [1]
	1-Naphthalen-1-yl-3-[(E)-(4-nitrophenyl)methylideneamino]thiourea	IC50	50000.0 [1]
	1-[(E)-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]methylideneamino]-3-naphthalen-1-ylthiourea	IC50	50000.0 [1]
	Methyl 2-[[2-[[6-(1,3-dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetyl]amino]benzoate	IC50	100000.0 [1]
	3-[[4-[(E)-[6-Ethoxycarbonyl-5-(4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]-2-methoxyphenoxy]methyl]benzoic acid	IC50	7100.0 [1]
	N'-[1-[4-(4-Fluorophenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]-N-(pyridin-3-ylmethyl)oxamide	IC50	50000.0 [1]
	N-(Furan-2-ylmethyl)-N'-[1-[4-(4-methoxyphenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]oxamide	IC50	50000.0 [1]
	2-[4-[3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]phenoxy]propanedioic acid	Ki	24780.0 [1]
	2-[4-[(E)-(6-Ethoxycarbonyl-7-methyl-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene)methyl]phenoxy]acetic acid	IC50	36500.0 [1]
	Ethyl (2E)-2-[(4-hydroxyphenyl)methylidene]-7-methyl-3-oxo-5-(4-propan-2-yloxyphenyl)-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate	IC50	42000.0 [1]
	8-[(1R,5S,6R)-6-[2,4-Dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one	IC50	11750.0 [1]
	Methyl 2-hydroxy-5-[5-[(Z)-[3-(3-methoxy-3-oxopropyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoate	IC50	44000.0 [1]
	5-(3-Chloro-2-methylphenyl)-N-(9,10-dioxo-9,10-dihydro-2-anthracenyl)-2-furamide	Ki	19170.0 [1]
	3-[[Benzyl-[(4-methoxyphenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	IC50	13030.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/hematopoietic-cell-protein-tyrosine-phosphatase-70z-pep-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/hematopoietic-cell-protein-tyrosine-phosphatase-70z-pep-inhibitors-ic50-ki.
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