Name: Histone-lysine N-methyltransferase EZH2 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Histone-lysine N-methyltransferase EZH2 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	S-Adenosyl-L-homocysteine	IC50	4800.0 ^[1]
	CID 68210102	IC50	1.0 ^[1], 2.0 ^[2], 280.0 ^[3]
	CID 68210102	Ki	0.5 ^[1]
	5-Chloro-3-[[4-(dimethylamino)cyclohexyl]-ethylamino]-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-2-ethylbenzamide	IC50	2.9 ^[1]
	5-Chloro-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl-[4-(pyrrolidine-1-carbonyl)cyclohexyl]amino]-2-methylbenzamide	IC50	21.4 ^[1]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Histone-lysine N-methyltransferase EZH2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2025, https://www.aatbio.com/data-sets/histone-lysine-n-methyltransferase-ezh2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 21). Quest Database™ Histone-lysine N-methyltransferase EZH2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-lysine-n-methyltransferase-ezh2-inhibitors-ic50-ki.
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