Histone-lysine N-methyltransferase SETD7 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	3-[3-[4-[4-(Trifluoromethyl)phenyl]-1H-indole-1-yl]benzylamino]benzoic acid	IC50	9930.0 [1], 19000.0 [2], 19500.0 [3], 22500.0 [4]
	Cyproheptadine	IC50	1000.0 [1], 3400.0 [2], 20000.0 [3]
	Cyproheptadine	Ki	15000.0 [1]
	S-Adenosyl-L-homocysteine	IC50	30000.0 [1]
	Sinefungin	IC50	2500.0 [1]
	CID 71268957	IC50	63000.0 [1]
	CID 46901937	IC50	40000.0 [1]
	Pimethixene	IC50	4300.0 [1]
	CID 71300326	IC50	2.0 [1]
	CID 44251522	IC50	40000.0 [1]
	CID 53315882	IC50	10000.0 [1]
	6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	IC50	100000.0 [1]
	N-(3-Nitrophenyl)-1,3-benzodioxole-5-carboxamide	IC50	61750.0 [1]
	CID 16451230	IC50	150000.0 [1]
	Ethyl 2-amino-4-methyl-5-[(3-nitrophenyl)carbamoyl]thiophene-3-carboxylate	IC50	4590.0 [1]
	1-Methyl-4-xanthen-9-ylidene-piperidine	IC50	16300.0 [1]
	4-Fluoren-9-ylidene-1-methyl-piperidine	IC50	41500.0 [1]
	1-Methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)piperidine	IC50	59100.0 [1]
	Methyl 2-amino-4-methyl-5-[(3-nitrophenyl)carbamoyl]thiophene-3-carboxylate	IC50	4880.0 [1]
	1-Methyl-4-(9h-xanthen-9-yl)piperazine	IC50	100000.0 [1]
	Carm1-IN-1	IC50	667000.0 [1]
	Piperidine, 4-(diphenylmethylene)-1-methyl-	IC50	94600.0 [1]
	PRMT5 Inhibitor C17	IC50	100000.0 [1]
	(2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]-N-[(3-phenyl-1H-pyrazol-5-yl)methyl]butanamide	IC50	100000.0 [1]
	5-Methyl-N-(3-nitrophenyl)furan-3-carboxamide	IC50	89180.0 [1]
	2-Amino-4-methyl-5-(3-nitroanilinocarbonyl)thiophene-3-carboxylic acid isobutyl ester	IC50	37670.0 [1]
	Carbamoyl 2-amino-4-methyl-5-[(3-nitrophenyl)carbamoyl]thiophene-3-carboxylate	IC50	49520.0 [1]
	Ethyl 2-amino-5-[(3-cyanophenyl)carbamoyl]-4-methylthiophene-3-carboxylate	IC50	61550.0 [1]
	1-Methyl-4-(9H-thioxanthen-9-yl)piperazine	IC50	100000.0 [1]
	1-Methyl-4-(9H-xanthen-9-yloxy)piperidine	IC50	100000.0 [1]
	1-Methyl-4-(9H-thioxanthen-9-yloxy)piperidine	IC50	100000.0 [1]
	1-Methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenyloxy)piperidine	IC50	100000.0 [1]
	4-Methyl-3-nitro-N-(3-nitrophenyl)benzamide	IC50	189700.0 [1]
	1-Ethyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)piperidine	IC50	7200.0 [1]
	1-Methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenyl)piperazine	IC50	100000.0 [1]
	1-Hexyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)piperidine	IC50	42000.0 [1]
	N-[(2-Methoxyphenyl)methyl]-2-[3-[[2-(methylamino)ethylamino]methyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide	IC50	100000.0 [1]
	2-[5-[[[(2S)-2-Aminopropanoyl]amino]methyl]thiophen-3-yl]-N-[(2-methoxyphenyl)methyl]-5-(trifluoromethyl)pyrazole-3-carboxamide	IC50	100000.0 [1]
	Cyproheptadine M (nor), acetylated	IC50	100000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(3-chlorophenyl)methyl]piperidin-4-one	IC50	174000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-phenacylpiperidin-4-one	IC50	149000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(2-methylphenyl)methyl]piperidin-4-one	IC50	667000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(3-methylphenyl)methyl]piperidin-4-one	IC50	667000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(4-methylphenyl)methyl]piperidin-4-one	IC50	333000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(2-chlorophenyl)methyl]piperidin-4-one	IC50	667000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-[(4-chlorophenyl)methyl]piperidin-4-one	IC50	600000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-(2-phenylethyl)piperidin-4-one	IC50	667000.0 [1]
	(3E,5E)-3,5-Bis[(3-bromo-4-hydroxyphenyl)methylidene]-1-(3-phenylpropyl)piperidin-4-one	IC50	667000.0 [1]
	N-[(6-Methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide	IC50	49000.0 [1]
	N-[4-(4-Aminophenyl)sulfonylphenyl]-4-phenylbenzamide	IC50	66400.0 [1]
	(2S,5S)-2-Amino-6-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]-5-(propylamino)hexanoic acid	IC50	2200.0 [1]
	N-[(4,6-Dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide	IC50	214000.0 [1]
	N-(3,4-Dimethoxyphenyl)-3-nitrobenzamide	IC50	30040.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 53 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Histone-lysine N-methyltransferase SETD7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/histone-lysine-n-methyltransferase-setd7-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Histone-lysine N-methyltransferase SETD7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-lysine-n-methyltransferase-setd7-inhibitors-ic50-ki.
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