Hypoxia-inducible factor 1-alpha inhibitor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N-Oxalylglycine	Ki	1200000.0 [1]
	Quercetin	IC50	10200.0 [1]
	4,6-Dioxoheptanoic acid	IC50	100000.0 [1]
	Pyridine-2,4-dicarboxylic acid	IC50	8600.0 [1]
	Daminozide	IC50	100000.0 [1]
	4-(Hydroxyamino)-4-oxobutanoic acid	IC50	100000.0 [1]
	4-Oxo-4-[4-[4-(1-naphthylcarbamoyloxymethyl)benzylamino]butylhydroxyamino]-2-butenoic acid	IC50	22000.0 [1]
	8-Hydroxyquinoline-4-carboxylic acid	IC50	21000.0 [1]
	(2R)-2-(Oxaloamino)-4-phenylbutanoic acid	Ki	83000.0 [1]
	(E)-3-(5((5-(4-Chlorophenyl)furan-2-YL)methylene)-4-oxo-2-thioxothiazolidin-3-YL)propanoic acid	IC50	66000.0 [1]
	2-[5-(2-Methoxyethanoylamino)-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic Acid	IC50	500000.0 [1]
	2-[5-[(5-Methyl-1,2-oxazol-3-yl)carbonylamino]-2-oxidanyl-phenyl]pyridine-4-carboxylic acid	IC50	473000.0 [1]
	2-(5-Acetamido-2-Oxidanyl-Phenyl)pyridine-4-Carboxylic Acid	IC50	500000.0 [1]
	2-[5-[(4-Hydroxyphenyl)carbonylamino]-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic Acid	IC50	500000.0 [1]
	2-[5-[2-(3-Methoxyphenyl)ethanoylamino]-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic Acid	IC50	500000.0 [1]
	3-(5-(2-Methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-N-(4-sulfamoylphenyl)propanamide	IC50	32100.0 [1]
	4-Hydrazinyl-4-oxobutanoic acid	IC50	100000.0 [1]
	N'1,N'1,N'4,N'4-Tetramethylsuccinohydrazide	IC50	100000.0 [1]
	4-(Isopropylamino)-4-oxobutanoic acid	IC50	100000.0 [1]
	6-[(E)-2-(2-Methoxyphenyl)ethenyl]-3-quinolin-2-yl-[1,3]thiazolo[2,3-c][1,2,4]triazole	IC50	47500.0 [1]
	6-[(2-Methoxyphenoxy)methyl]-3-quinolin-2-yl-[1,3]thiazolo[2,3-c][1,2,4]triazole	IC50	41400.0 [1]
	2-[(5E)-5-[[3-(4-Ethylsulfanylphenyl)-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid	IC50	36200.0 [1]
	N-(2,1,3-Benzoxadiazol-4-yl)-3-[(5Z)-5-[(3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanamide	IC50	73100.0 [1]
	N-(2,1,3-Benzoxadiazol-4-yl)-3-[(5E)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanamide	IC50	48600.0 [1]
	N-(2,1,3-Benzoxadiazol-4-yl)-2-[(5Z)-5-[(3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetamide	IC50	45300.0 [1]
	4-((Dimethylamino)oxy)-4-oxobutanoic acid	IC50	100000.0 [1]
	4-[Dimethylamino(methyl)amino]-4-oxobutanoic acid	IC50	100000.0 [1]
	(3-Carboxypropanoylamino)-trimethylazanium	IC50	100000.0 [1]
	4-(2-Methylhydrazinyl)-4-oxobutanoic acid	IC50	100000.0 [1]
	N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-8-hydroxyquinoline-5-carboxamide	IC50	25000.0 [1]
	2-[4-[[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]carbamoyl]pyridin-2-yl]pyridine-4-carboxylic acid	IC50	100000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 31 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Hypoxia-inducible factor 1-alpha inhibitor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 May. 2025, https://www.aatbio.com/data-sets/hypoxia-inducible-factor-1-alpha-inhibitor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, May 20). Quest Database™ Hypoxia-inducible factor 1-alpha inhibitor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/hypoxia-inducible-factor-1-alpha-inhibitor-inhibitors-ic50-ki.
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