Immunoglobulin epsilon Fc receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Batimastat	IC50	100.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide	IC50	1900.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(naphthalen-2-ylmethyl)butanediamide	IC50	1000.0 [1]
	(2R)-2-Benzyl-N-[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxybutanediamide	IC50	5000.0 [1]
	(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(phenylsulfanylmethyl)butanediamide	IC50	40.0 [1]
	Methylamino-phenylalanyl-leucyl-hydroxamic acid	IC50	1000.0 [1]
	(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(phenacylsulfanylmethyl)butanediamide	IC50	16.0 [1]
	(2S,3R)-N-Hydroxy-2-[[(2E)-2-hydroxyimino-2-phenylethyl]sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamide	IC50	12.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-(1-benzothiophen-2-ylmethyl)-N',3-dihydroxybutanediamide	IC50	20.0 [1]
	(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-phenylbutanediamide	IC50	1600.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N',3-dihydroxy-2-(naphthalen-2-ylmethyl)butanediamide	IC50	600.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-(naphthalen-2-ylmethyl)butanediamide	IC50	20.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-(cyclopentylmethyl)-N'-hydroxybutanediamide	IC50	200.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-(cyclohexylmethyl)-N'-hydroxybutanediamide	IC50	3700.0 [1]
	(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide	IC50	20000.0 [1]
	(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-cyclohexyl-N'-hydroxybutanediamide	IC50	5000.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-propan-2-ylsulfanylbutanediamide	IC50	8000.0 [1]
	(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(4-phenylphenyl)butanediamide	IC50	20000.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(propan-2-ylsulfanylmethyl)butanediamide	IC50	20000.0 [1]
	(2R)-2-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-1-N-hydroxybutane-1,2,4-tricarboxamide	IC50	20000.0 [1]
	(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-naphthalen-1-ylbutanediamide	IC50	20000.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-methylbutanediamide	IC50	20000.0 [1]
	(2S)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-2-[(dimethylamino)methyl]-N'-hydroxybutanediamide	IC50	20000.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N',2-dihydroxybutanediamide	IC50	20000.0 [1]
	(2R)-N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-phenylethyl)butanediamide	IC50	5000.0 [1]
	N-[(2S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxybutanediamide	IC50	20000.0 [1]
	(2S)-2-Benzyl-N-[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]-N'-hydroxybutanediamide	IC50	20000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-[(6-fluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamide	IC50	220.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-(quinolin-6-ylmethyl)butanediamide	IC50	1000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-[(7-fluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamide	IC50	100.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-(1,3-benzothiazol-2-ylmethyl)-N',3-dihydroxybutanediamide	IC50	320.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N',3-dihydroxy-2-[(7-hydroxynaphthalen-2-yl)methyl]butanediamide	IC50	760.0 [1]
	(2S,3R)-3-(1-Benzofuran-2-ylmethyl)-N,2-dihydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamide	IC50	100.0 [1]
	(2S,3R)-3-(1-Benzothiophen-3-ylmethyl)-N,2-dihydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamide	IC50	1000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-[(3-chloro-1-benzothiophen-2-yl)methyl]-N',3-dihydroxybutanediamide	IC50	10000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N',3-dihydroxy-2-[(7-phenylmethoxynaphthalen-2-yl)methyl]butanediamide	IC50	20000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-2-[(6,7-difluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamide	IC50	1000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-(quinolin-3-ylmethyl)butanediamide	IC50	20.0 [1]
	(2R,3S)-N-[(2S)-3,3-Dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(5,6,7,8-tetrahydronaphthalen-2-ylmethyl)butanediamide	IC50	10000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-2-[(7-fluoronaphthalen-2-yl)methyl]-N',3-dihydroxybutanediamide	IC50	80.0 [1]
	(2S,3R)-N,2-Dihydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(naphthalen-2-ylmethyl)butanediamide	IC50	400.0 [1]
	(2S,3R)-N,2-Dihydroxy-3-[(7-methoxy-1-benzofuran-2-yl)methyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamide	IC50	20000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(phenacylsulfanylmethyl)butanediamide	IC50	20.0 [1]
	(2S,3R)-2-(Benzylsulfanylmethyl)-N-hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamide	IC50	30.0 [1]
	(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-[(4-nitrophenyl)sulfanylmethyl]butanediamide	IC50	100.0 [1]
	2-[(2S,3R)-2-(Hydroxycarbamoyl)-5-methyl-3-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]hexyl]sulfanylbenzoic acid	IC50	3700.0 [1]
	Methyl 2-[(2S,3R)-2-(hydroxycarbamoyl)-5-methyl-3-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]hexyl]sulfanylbenzoate	IC50	100.0 [1]
	Methyl 4-[(2S,3R)-2-(hydroxycarbamoyl)-5-methyl-3-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]hexyl]sulfanylbenzoate	IC50	50.0 [1]
	(2S,3R)-N-Hydroxy-2-[[(2E)-2-hydroxyimino-2-(4-phenylphenyl)ethyl]sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamide	IC50	130.0 [1]
	(2S,3R)-N-Hydroxy-2-[(4-hydroxyphenyl)sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamide	IC50	40.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(thiophen-2-ylsulfanylmethyl)butanediamide	IC50	30.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-(thiophen-2-ylsulfanylmethyl)butanediamide	IC50	160.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-3-[[(2E)-2-hydroxyimino-2-phenylethyl]sulfanylmethyl]-2-(2-methylpropyl)butanediamide	IC50	100.0 [1]
	(2S,3R)-N-Hydroxy-2-[[(2E)-2-methoxyimino-2-phenylethyl]sulfanylmethyl]-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)butanediamide	IC50	80.0 [1]
	(2R)-2-Benzyl-N'-hydroxy-N-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]butanediamide	IC50	20000.0 [1]
	2-[(2S,3R)-3-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2-(hydroxycarbamoyl)-5-methylhexyl]sulfanylacetic acid	IC50	1000.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(sulfanylmethyl)butanediamide	IC50	130.0 [1]
	(2R)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide	IC50	3000.0 [1]
	S-[(2S,3R)-3-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2-(hydroxycarbamoyl)-5-methylhexyl] ethanethioate	IC50	1000.0 [1]
	Methyl 2-[(2S,3R)-3-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2-(hydroxycarbamoyl)-5-methylhexyl]sulfanylacetate	IC50	13.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-3-(cyanomethylsulfanylmethyl)-N'-hydroxy-2-(2-methylpropyl)butanediamide	IC50	100.0 [1]
	(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-[[2-oxo-2-(4-phenylphenyl)ethyl]sulfanylmethyl]butanediamide	IC50	380.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-3-[[(2E)-2-(4-chlorophenyl)-2-hydroxyiminoethyl]sulfanylmethyl]-N'-hydroxy-2-(2-methylpropyl)butanediamide	IC50	60.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-[[(2Z)-2-methoxyimino-2-phenylethyl]sulfanylmethyl]butanediamide	IC50	100.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-[[(2Z)-2-hydroxyimino-2-phenylethyl]sulfanylmethyl]butanediamide	IC50	130.0 [1]
	(2R,3S)-N-[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]-2-benzyl-N'-hydroxy-3-(phenacylsulfanylmethyl)butanediamide	IC50	210.0 [1]
	(2R,3S)-3-[(2-Amino-2-oxoethyl)sulfanylmethyl]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide	IC50	100.0 [1]
	(3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-[[(2S)-1,2,3,4-tetrahydronaphthalen-2-yl]methyl]butanediamide	IC50	70.0 [1]
	(3S)-N-[(2S)-1-Amino-3,3-dimethyl-1-oxobutan-2-yl]-N',3-dihydroxy-2-[[(2R)-1,2,3,4-tetrahydronaphthalen-2-yl]methyl]butanediamide	IC50	70.0 [1]
	(2R,3S)-N-[(2S)-3,3-Dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(naphthalen-2-ylmethyl)butanediamide	IC50	230.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 70 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Immunoglobulin epsilon Fc receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/immunoglobulin-epsilon-fc-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Immunoglobulin epsilon Fc receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/immunoglobulin-epsilon-fc-receptor-inhibitors-ic50-ki.
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