Induced myeloid leukemia cell differentiation protein Mcl-1/Bcl-2-like protein 11 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Marinopyrrole A	IC50	8900.0 [1]
	(4-Chloro-2-hydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanone	IC50	6500.0 [1]
	[4,5-Dichloro-3-[2,3-dichloro-5-(5-fluoro-2-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrol-2-yl]-(2-hydroxyphenyl)methanone	IC50	8900.0 [1]
	2-[4-[1-[2-[4-(Carboxymethylsulfanyl)-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-3-hydroxyphenyl]sulfanylacetic acid	IC50	6100.0 [1]
	[4,5-Dichloro-3-[2,3-dichloro-5-(2-fluoro-6-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrol-2-yl]-(2-hydroxyphenyl)methanone	IC50	13100.0 [1]
	(4-Chloro-2-methoxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-methoxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanone	IC50	8000.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(1-phenyltriazol-4-yl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-(1-phenyltriazol-4-yl)phenyl]methanone	IC50	1500.0 [1]
	[4-(1-Cyclohexyltriazol-4-yl)-2-hydroxyphenyl]-[4,5-dichloro-1-[4,5-dichloro-2-[4-(1-cyclohexyltriazol-4-yl)-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]methanone	IC50	1400.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethenyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethenyl-2-hydroxyphenyl)methanone	IC50	3700.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethynyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethynyl-2-hydroxyphenyl)methanone	IC50	3900.0 [1]
	Ethyl 2-[4-[2-chloro-4-[4,5-dichloro-1-[4,5-dichloro-2-[5-chloro-4-[1-(2-ethoxy-2-oxoethyl)triazol-4-yl]-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-5-hydroxyphenyl]triazol-1-yl]acetate	IC50	7800.0 [1]
	[1-[2-[4-(1-Benzyltriazol-4-yl)-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrol-2-yl]-[4-(1-benzyltriazol-4-yl)-2-hydroxyphenyl]methanone	IC50	3300.0 [1]
	2-[4-[4-[1-[2-[4-[1-(Carboxymethyl)triazol-4-yl]-5-chloro-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-2-chloro-5-hydroxyphenyl]triazol-1-yl]acetic acid	IC50	5200.0 [1]
	Ethyl 2-[4-[4-[4,5-dichloro-1-[4,5-dichloro-2-[4-[1-(2-ethoxy-2-oxoethyl)triazol-4-yl]-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetate	IC50	18400.0 [1]
	2-[4-[4-[1-[2-[4-[1-(Carboxymethyl)triazol-4-yl]-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetic acid	IC50	16500.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethyl-2-hydroxyphenyl)methanone	IC50	2100.0 [1]
	[4-[4,5-Dichloro-3-[2,3-dichloro-5-(2-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrole-2-carbonyl]-3-hydroxyphenyl] trifluoromethanesulfonate	IC50	1000.0 [1]
	Ethyl 2-[4-[4,5-dichloro-1-[4,5-dichloro-2-[4-(2-ethoxy-2-oxoethyl)sulfanyl-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]sulfanylacetate	IC50	1800.0 [1]
	[1-[2-(4-Benzylsulfanyl-2-hydroxybenzoyl)-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrol-2-yl]-(4-benzylsulfanyl-2-hydroxyphenyl)methanone	IC50	700.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-[(4-methoxyphenyl)methylsulfanyl]benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-[(4-methoxyphenyl)methylsulfanyl]phenyl]methanone	IC50	700.0 [1]
	[4-[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxy-4-phosphonobenzoyl)-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]phosphonic acid	IC50	10900.0 [1]
	Tert-butyl 2-[4-[2-chloro-4-[4,5-dichloro-1-[4,5-dichloro-2-[5-chloro-2-hydroxy-4-[1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]triazol-4-yl]benzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-5-hydroxyphenyl]triazol-1-yl]acetate	IC50	1600.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(1-octyltriazol-4-yl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[4-(1-heptyltriazol-4-yl)-2-hydroxyphenyl]methanone	IC50	600.0 [1]
	Tert-butyl 2-[4-[4-[4,5-dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-[1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]triazol-4-yl]benzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetate	IC50	5100.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-(2-methoxybenzoyl)-1-methylpyrrol-3-yl]pyrrol-2-yl]-(2-methoxyphenyl)methanone	IC50	15500.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1-methylpyrrol-3-yl]pyrrol-2-yl]-(2-hydroxyphenyl)methanone	IC50	100000.0 [1]
	Marinopyrrole D	IC50	3900.0 [1]
	[8a-(Methoxymethoxymethyl)-3-methyl-6-[2-methyl-1-(2-methylprop-2-enylamino)-1-oxopropan-2-yl]-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] N-(3-chlorophenyl)carbamate	IC50	8300.0 [1]
	Benzyl 2-[(2S,4aR,5S,8aR)-4a-(methoxymethoxymethyl)-7-methyl-5-phenylmethoxy-2,5,6,8a-tetrahydro-1H-naphthalen-2-yl]-2-methylpropanoate	IC50	13100.0 [1]
	[(1S,4Ar,6S,8aR)-6-[1-[(4-bromophenyl)methylamino]-2-methyl-1-oxopropan-2-yl]-8a-(methoxymethoxymethyl)-3-methyl-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] N-cyclohexylcarbamate	IC50	17000.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-fluoro-2-hydroxyphenyl)methanone	IC50	9600.0 [1]
	(3-Chloro-2-hydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanone	IC50	4100.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(trifluoromethyl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-(trifluoromethyl)phenyl]methanone	IC50	8100.0 [1]
	(5-Chloro-2,4-dihydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(5-chloro-2,4-dihydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanone	IC50	10700.0 [1]
	[4,5-Dichloro-1-[4,5-dichloro-2-(2,4-dihydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(2,4-dihydroxyphenyl)methanone	IC50	39500.0 [1]
	(5-Chloro-2-hydroxy-4-methylphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(5-chloro-2-hydroxy-4-methylbenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanone	IC50	2600.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 36 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Induced myeloid leukemia cell differentiation protein Mcl-1/Bcl-2-like protein 11 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/induced-myeloid-leukemia-cell-differentiation-protein-mcl-1-bcl-2-like-protein-11-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Induced myeloid leukemia cell differentiation protein Mcl-1/Bcl-2-like protein 11 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/induced-myeloid-leukemia-cell-differentiation-protein-mcl-1-bcl-2-like-protein-11-inhibitors-ic50-ki.
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