Inosine-5'-monophosphate dehydrogenase (IMPDH) Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Mycophenolic acid	IC50	20000.0 [1]
	Inosinic acid	Ki	250.0 [1]
	4-Amino-7-chloroquinoline	IC50	168000.0 [1]
	Merimepodib	IC50	7.0 [1]
	6-Chloroinosine monophosphate	Ki	62000.0 [1]
	4-Hydroxycarbazole	IC50	54000.0 [1]
	3-Cyanoindole	IC50	32000.0 [1]
	5-Cyanoindole	IC50	99000.0 [1]
	[(2R,3R,4S,5R)-5-(2-Amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	38000.0 [1]
	N'-Tert-butyl-N-[4-(4-methyl-1,3-oxazol-5-yl)phenyl]oxamide	IC50	14000.0 [1]
	N'-Tert-butyl-N-[4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	20000.0 [1]
	N'-Tert-butyl-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	40.0 [1]
	N'-Tert-butyl-N-[3-chloro-4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	180.0 [1]
	[(2S,3R,4S)-3,4-Dihydroxy-5-(2-methyl-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate	Ki	600000.0 [1]
	3-Methoxy-4-(oxazol-5-yl)aniline	IC50	19000.0 [1]
	(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)hex-4-enoic acid	IC50	20.0 [1]
	3-[(4-Pyridinylthio)acetyl]-5-methoxy-1H-indole	IC50	32000.0 [1]
	[(2R,3S,4R)-5-[2-[(E)-2-Fluoroethenyl]-6-oxo-1H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	1110.0 [1]
	[(2S,3R,4S)-5-(2-Chloro-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate	Ki	120000.0 [1]
	[(2S,3R,4S)-3,4-Dihydroxy-5-(6-oxo-2-propyl-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate	Ki	190000.0 [1]
	[(2S,3R,4S)-3,4-Dihydroxy-5-(2-methoxy-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate	Ki	46000.0 [1]
	N'-Tert-butyl-N-[3-ethoxy-4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	1300.0 [1]
	N'-Tert-butyl-N-[3-methoxy-4-(1H-pyrrol-2-yl)phenyl]oxamide	IC50	2400.0 [1]
	N'-Tert-butyl-N-[3-methoxy-4-(1H-1,2,4-triazol-5-yl)phenyl]oxamide	IC50	15000.0 [1]
	N'-Tert-butyl-N-[3-methoxy-4-(4-methyl-1,3-oxazol-5-yl)phenyl]oxamide	IC50	430.0 [1]
	N'-Tert-butyl-N-[4-(furan-2-yl)-3-methoxyphenyl]oxamide	IC50	8100.0 [1]
	N-[4-(4-Benzyl-1,3-oxazol-5-yl)-3-methoxyphenyl]-N'-tert-butyloxamide	IC50	35000.0 [1]
	N'-Tert-butyl-N-[4-(4-butyl-1,3-oxazol-5-yl)-3-methoxyphenyl]oxamide	IC50	27000.0 [1]
	N'-Tert-butyl-N-[3-methoxy-4-(1,3-oxazol-4-yl)phenyl]oxamide	IC50	470.0 [1]
	N'-Tert-butyl-N-(3,4-dimethoxyphenyl)oxamide	IC50	21000.0 [1]
	N'-Tert-butyl-N-[3-methoxy-4-(1,3-thiazol-5-yl)phenyl]oxamide	IC50	910.0 [1]
	N'-Tert-butyl-N-[3-fluoro-4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	730.0 [1]
	6,7-Dimethyl-4-oxo-2,3-dihydrochromene-3-carbonitrile	IC50	88000.0 [1]
	N'-Tert-butyl-N-[4-(1,3-oxazol-5-yl)-3-(trifluoromethyl)phenyl]oxamide	IC50	18000.0 [1]
	N'-Tert-butyl-N-[4-methoxy-3-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	16000.0 [1]
	N'-Tert-butyl-N-[3-methyl-4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	200.0 [1]
	N'-Tert-butyl-N-[3-ethyl-4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	1200.0 [1]
	N'-Tert-butyl-N-[3-hydroxy-4-(1,3-oxazol-5-yl)phenyl]oxamide	IC50	4400.0 [1]
	(2S)-2-[(2E)-2-[2-(4-Amino-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)ethylidene]cyclopentyl]propanoic acid	IC50	7.0 [1]
	4-Hydroxy-2-methylacetophenone	IC50	620000.0 [1]
	4-Methoxy-1-naphthonitrile	IC50	31000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 41 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Inosine-5'-monophosphate dehydrogenase (IMPDH) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/inosine-5-monophosphate-dehydrogenase-impdh-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Inosine-5'-monophosphate dehydrogenase (IMPDH) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/inosine-5-monophosphate-dehydrogenase-impdh-inhibitors-ic50-ki.
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