Insulin-like growth factor I receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Staurosporine	IC50	200.0 [1]
	Bms-536924	IC50	100.0 [1]
	Linsitinib	IC50	13.0 [1]
	N-[4-[[5,5-Dimethyl-2,4-dioxo-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidin-1-yl]methyl]pyridin-2-yl]acetamide	IC50	28.0 [1]
	1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea	IC50	12000.0 [1]
	2-(5,6-Dimethoxy-1-methyl-1h-indol-3-yl)-1h-pyrrolo[2,3-b]pyridine	IC50	35.0 [1]
	2-Fluoro-6-[[2-[2-methoxy-4-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide	IC50	2.0 [1]
	N-[(3-{4-Amino-5-[3-(Benzyloxy)phenyl]-7h-Pyrrolo[2,3-D]pyrimidin-7-Yl}cyclobutyl)methyl]acetamide	IC50	50.0 [1]
	Nvp-aew541	IC50	20.0 [1], 60.0 [2], 61.0 [3], 65.0 [4]
	N-(2,6-Difluorophenyl)-5-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]-2-methoxybenzamide	IC50	22.0 [1], 27.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-5-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]-2-methoxybenzamide	Ki	1.6 [1]
	2-[[2-[[1-[2-(Dimethylamino)acetyl]-5-methoxy-2,3-dihydroindol-6-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-6-fluorobenzamide	IC50	1.0 [1], 54.0 [2], 56.0 [3], 487.0 [4]
	4-[[1,3-Benzodioxol-5-yl-[(3,4-dihydroxyphenyl)methyl]amino]methyl]benzene-1,2-diol	IC50	170.0 [1], 3900.0 [2], 5300.0 [3], 6200.0 [4]
	N-[4-[4-Amino-1-[4-(4-methylpiperazin-1-yl)cyclohexyl]pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-7-chloro-1,3-benzoxazol-2-amine	IC50	12.5 [1], 77.0 [2], 207.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	5.0 [1], 36.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	Ki	5.2 [1]
	N-[4-[4-Amino-1-[4-(4-methylpiperazin-1-yl)cyclohexyl]pyrazolo[3,4-d]pyrimidin-3-yl]-2-fluorophenyl]-7-chloro-1,3-benzoxazol-2-amine	IC50	7.5 [1], 72.0 [2], 87.0 [3]
	Bms-754807	IC50	2.0 [1], 2.1 [2], 8.4 [3]
	CID 9825149	IC50	50.0 [1], 78.0 [2], 323.0 [3], 500.0 [4]
	3-Cyclobutyl-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine	IC50	79.0 [1], 80.0 [2], 86.0 [3]
	4-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-3-(6-imidazol-1-yl-4-methyl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	180.0 [1], 370.0 [2]
	3-[cis-3-(4-Methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine	IC50	19.0 [1], 37.0 [2], 58.0 [3], 65.0 [4]
	cis-3-[4-Amino-7-(3-azetidin-1-ylmethyl-cyclobutyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-phenol	IC50	420.0 [1], 454.0 [2]
	7-[3-(Azetidin-1-ylmethyl)cyclobutyl]-5-[3-[[(2S)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-4-amine	IC50	12.0 [1], 80.0 [2], 84.0 [3]
	cis-3-(3-Pyrrolidin-1-ylmethylcyclobutyl)-1-(3-benzyloxyphenyl)-imidazo[1,5-a]pyrazin-8-ylamine	IC50	89.0 [1], 116.0 [2], 401.0 [3], 621.0 [4]
	cis-3-(3-Azetidin-1-ylmethylcyclobutyl)-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-ylamine	IC50	20.0 [1], 35.0 [2], 42.0 [3]
	2-Fluoro-6-[[2-[2-methoxy-5-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide	IC50	4.0 [1], 160.0 [2], 201.0 [3]
	2-Fluoro-6-[[2-[2-methoxy-4-methyl-5-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide	IC50	20.0 [1], 270.0 [2]
	1-[4-[4-[(5-Chloro-4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methoxyphenyl]piperazin-1-yl]ethanone	IC50	9.0 [1], 10.0 [2], 17.0 [3]
	trans-3-(8-Amino-1-(3-(benzyloxy)phenyl)imidazo[1,5-a]pyrazin-3-yl)cyclobutanecarboxamide	IC50	526.0 [1], 554.0 [2], 1710.0 [3], 2080.0 [4]
	trans-4-(8-Amino-1-(3-(benzyloxy)phenyl)imidazo[1,5-a]pyrazin-3-yl)cyclohexanecarboxamide	IC50	221.0 [1], 775.0 [2], 898.0 [3], 8570.0 [4]
	cis-3-(4-(Aminomethyl)cyclohexyl)-1-(3-(benzyloxy)phenyl)imidazo[1,5-a]pyrazin-8-amine	IC50	119.0 [1], 228.0 [2], 534.0 [3], 560.0 [4]
	N-(2,6-Difluorophenyl)-3-[3-[2-[2-methoxy-4-(4-piperidin-1-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	2.0 [1], 38.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[3-[2-(dimethylamino)ethoxy]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	1.0 [1], 100.0 [2], 177.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[4-(4-piperidin-1-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	2.0 [1], 87.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[2-methoxy-4-(4-morpholin-4-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	2.0 [1], 41.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[2-methoxy-4-(4-pyrrolidin-1-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	2.0 [1], 38.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[4-[4-[(3R)-3-fluoropyrrolidin-1-yl]piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	2.0 [1], 40.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	2.0 [1], 28.0 [2], 100.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[4-[4-[(2R,6S)-2,6-dimethylmorpholin-4-yl]piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	4.0 [1], 68.0 [2], 100.0 [3]
	3-[3-[2-[4-[4-(4-Acetylpiperazin-1-yl)piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide	IC50	3.0 [1], 65.0 [2], 100.0 [3]
	N-[4-[4-Amino-1-[4-(4-propan-2-ylpiperazin-1-yl)cyclohexyl]pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-7-chloro-1,3-benzoxazol-2-amine	IC50	45.1 [1], 174.0 [2]
	N-[4-[4-Amino-1-[4-[4-(3-methoxypropyl)piperazin-1-yl]cyclohexyl]pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-7-chloro-1,3-benzoxazol-2-amine	IC50	72.4 [1], 424.0 [2]
	1-[4-[3-[4-Amino-5-[2-fluoro-5-[[(2S)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone	IC50	12.0 [1], 13.0 [2], 16.0 [3], 54.0 [4]
	3-[8-Amino-1-(4-methoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol	IC50	0.7 [1], 3.0 [2], 7.1 [3], 320.0 [4]
	4-[2-[3-(2-Aminoethyl)-1-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]indol-5-yl]oxyethyl]phenol	IC50	1020.0 [1], 1060.0 [2], 1070.0 [3]
	4-[2-[[6-Amino-9-(5-phenylpentyl)-5,6,7,8-tetrahydrocarbazol-3-yl]oxy]ethyl]phenol	IC50	930.0 [1], 990.0 [2], 1220.0 [3]
	N-(2,6-Difluorophenyl)-3-[3-[2-[2-methoxy-4-[4-[4-(2-methylsulfonylethyl)piperazin-1-yl]cyclohexyl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	100.0 [1]
	N-[[3-[4-Amino-5-[3-[(2-chlorophenyl)methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]methyl]acetamide	IC50	50.0 [1], 500.0 [2]
	N-[[3-[4-Amino-5-(3-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]methyl]acetamide	IC50	50.0 [1], 5000.0 [2]
	Crizotinib	IC50	143.0 [1], 1000.0 [2], 10000.0 [3]
	Entrectinib	IC50	122.0 [1], 263.0 [2]
	CID 25182616	IC50	2.0 [1], 85.0 [2], 310.0 [3]
	3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)pyrrole-2,5-dione	IC50	6967.0 [1], 9900.0 [2], 13000.0 [3]
	5-Fluoro-2-[[2-[2-methoxy-4-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide	IC50	0.8 [1], 0.9 [2], 60.0 [3]
	3-(5-(1H-Imidazol-1-yl)-7-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one	IC50	3500.0 [1]
	1-(3-Benzyloxy-phenyl)-3-cyclobutyl-imidazo[1,5-a]pyrazin-8-ylamine	IC50	606.0 [1], 1160.0 [2]
	4-[2-(4-Chloropyrazol-1-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	120.0 [1], 376.0 [2]
	4-[2-(5-Chloro-1-methylimidazol-4-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	38.0 [1], 336.0 [2]
	4-[2-(5-Chloro-1-ethylimidazol-4-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	83.0 [1], 469.0 [2]
	4-[2-(5-Bromo-1-methylimidazol-4-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	75.0 [1], 343.0 [2]
	4-[2-(1-Methylimidazol-4-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	190.0 [1], 521.0 [2]
	4-[2-(1-Ethylimidazol-4-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	480.0 [1], 583.0 [2]
	4-[2-[1-(2-Methoxyethyl)imidazol-4-yl]ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	550.0 [1], 1510.0 [2]
	3-(4-Methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-4-[2-(1-propan-2-ylimidazol-4-yl)ethylamino]-1H-pyridin-2-one	IC50	360.0 [1], 365.0 [2]
	4-[2-[5-Chloro-1-(2-methoxyethyl)imidazol-4-yl]ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	290.0 [1], 622.0 [2]
	4-[2-(5-Chloro-1-propan-2-ylimidazol-4-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	360.0 [1], 1140.0 [2]
	4-[2-(2,5-Dichloro-1-methylimidazol-4-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one	IC50	160.0 [1], 306.0 [2]
	3-(4-Methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-4-[2-(4-methylpyrazol-1-yl)ethylamino]-1H-pyridin-2-one	IC50	110.0 [1], 397.0 [2]
	1-[2-[[3-(4-Methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-2-oxo-1H-pyridin-4-yl]amino]ethyl]pyrazole-4-carbonitrile	IC50	680.0 [1], 821.0 [2]
	Ethyl 1-[2-[[3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-2-oxo-1H-pyridin-4-yl]amino]ethyl]pyrazole-4-carboxylate	IC50	68.0 [1], 531.0 [2]
	Methyl 1-[2-[[3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-2-oxo-1H-pyridin-4-yl]amino]ethyl]pyrazole-4-carboxylate	IC50	91.0 [1], 711.0 [2]
	3-(4-Methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-4-(2-pyrazol-1-ylethylamino)-1H-pyridin-2-one	IC50	330.0 [1], 613.0 [2]
	3-[2-[(2-Chlorophenyl)methyl]-3H-benzimidazol-5-yl]-1-(4-morpholin-4-ylcyclohexyl)pyrazolo[3,4-d]pyrimidin-4-amine	IC50	36.0 [1], 37.0 [2], 90.0 [3]
	4-[3-Chloro-4-(1-ethyl-4,5-dimethylimidazol-2-yl)sulfanylanilino]-7-[3-(4-ethylpiperazin-1-yl)propoxy]-6-methoxyquinoline-3-carbonitrile	IC50	9.0 [1], 90.0 [2]
	4-Fluoro-2-[[2-[2-methoxy-4-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide	IC50	0.7 [1], 0.8 [2], 130.0 [3]
	2,3-Difluoro-6-[[2-[2-methoxy-4-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide	IC50	1.3 [1], 213.0 [2]
	2,4-Difluoro-6-[[2-[2-methoxy-4-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamide	IC50	0.8 [1], 90.0 [2]
	3-(2-Benzyl-3H-benzimidazol-5-yl)-1-(4-morpholin-4-ylcyclohexyl)pyrazolo[3,4-d]pyrimidin-4-amine	IC50	64.0 [1], 94.0 [2]
	1-(4-Morpholin-4-ylcyclohexyl)-3-[2-(thiophen-2-ylmethyl)-3H-benzimidazol-5-yl]pyrazolo[3,4-d]pyrimidin-4-amine	IC50	23.0 [1], 25.0 [2], 56.0 [3]
	3-[2-[(2-Methoxyphenyl)methyl]-3H-benzimidazol-5-yl]-1-(4-morpholin-4-ylcyclohexyl)pyrazolo[3,4-d]pyrimidin-4-amine	IC50	81.0 [1], 142.0 [2]
	N-[5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide	IC50	1441.0 [1], 2350.0 [2]
	N-[5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-yl]-2-(2-methoxyethylamino)-4-(4-methylpiperazin-1-yl)benzamide	IC50	1103.0 [1], 2112.0 [2]
	N-(2,6-Difluorophenyl)-3-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide	IC50	7.0 [1], 100.0 [2]
	1-[4-[3-[4-Amino-5-[3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone	IC50	9.4 [1], 10.0 [2], 16.0 [3]
	1-(2-Aminopyrid-4-yl-methyl)-5,5-dimethyl-3-(4-trifluoromethylsulfanylphenyl)imidazolidine-2,4-dione	IC50	34.0 [1], 92.0 [2]
	1-[[2-(Ethylamino)pyridin-4-yl]methyl]-5,5-dimethyl-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione	IC50	47.0 [1], 154.0 [2]
	5,5-Dimethyl-1-(pyridin-4-ylmethyl)-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione	IC50	117.0 [1], 264.0 [2]
	5,5-Dimethyl-1-[[2-(methylamino)pyridin-4-yl]methyl]-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione	IC50	43.0 [1], 202.0 [2]
	1-[4-[3-[4-Amino-5-[2-fluoro-5-[[(2R)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone	IC50	47.0 [1], 64.0 [2], 159.0 [3]
	[3-[4-Amino-5-[3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]methanol	IC50	11.0 [1], 33.0 [2], 128.0 [3]
	[3-[4-Amino-5-[3-[(4-methyl-7-oxabicyclo[2.2.1]heptan-1-yl)methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]methanol	IC50	29.0 [1], 47.0 [2], 183.0 [3]
	7-[3-(Azetidin-1-ylmethyl)cyclobutyl]-5-[3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-4-amine	IC50	14.0 [1], 46.0 [2], 53.0 [3]
	5-[3-[[(2S)-Oxolan-2-yl]methoxy]phenyl]-7-[3-[(1-oxo-1,4-thiazinan-4-yl)methyl]cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine	IC50	80.0 [1], 92.0 [2], 232.0 [3]
	1-[4-[3-[4-Amino-5-[2-fluoro-3-[[(2S)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone	IC50	15.0 [1], 16.0 [2]
	5-[2-Fluoro-5-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]-7-[3-[(1-oxo-1,4-thiazinan-4-yl)methyl]cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine	IC50	7.3 [1], 8.3 [2], 8.9 [3]
	5-[2-Fluoro-5-[[(2S)-oxolan-2-yl]methoxy]phenyl]-7-[3-[(1-oxo-1,4-thiazinan-4-yl)methyl]cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine	IC50	14.0 [1], 16.0 [2], 27.0 [3]
	1-[4-[3-[4-Amino-5-[2-fluoro-5-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone	IC50	7.8 [1], 12.0 [2], 13.0 [3]
	1-[4-[3-[4-Amino-5-[2-fluoro-3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone	IC50	2.8 [1], 4.6 [2], 9.6 [3]
	3-[8-Amino-1-(4-ethoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol	IC50	0.6 [1], 4.0 [2], 440.0 [3]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Insulin-like growth factor I receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/insulin-like-growth-factor-i-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Insulin-like growth factor I receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/insulin-like-growth-factor-i-receptor-inhibitors-ic50-ki.
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