Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-Propen-1-one, 1-(4-acetyl-1-piperazinyl)-3-(4-((2-(1-methylethyl)phenyl)thio)-3-nitrophenyl)-	IC50	30.0 [1], 44.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(5-methylsulfonylfuran-2-yl)propanoic acid	IC50	1.2 [1], 96.0 [2]
	(S)-2-(2-Bromo-benzoylamino)-3-(1H-indol-3-yl)-propionic acid	IC50	1700.0 [1], 1720.0 [2]
	(S)-2-(2-Bromo-benzoylamino)-3-(3H-imidazol-4-yl)-propionic acid	IC50	750.0 [1]
	Unii-nug7541qvz	IC50	40.0 [1], 80.0 [2]
	3-[3-Chloro-4-(2,4-dichlorophenylthio)phenyl]-1-(4-acetylpiperazino)-2-propene-1-one	IC50	130.0 [1], 140.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(thiophene-2-carbonylamino)propanoic acid	IC50	5.0 [1], 9.0 [2], 950.0 [3]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(thiophene-2-carbonylamino)propanoic acid	IC50	22.0 [1], 1500.0 [2]
	Lifitegrast	IC50	9.0 [1], 74.0 [2]
	N-(3-Hydroxypropyl)-5-methyl-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]pyrazole-4-carboxamide	IC50	5000.0 [1]
	(2S)-2-[(3S,5R)-5-Methyl-3-(2-methylpropyl)-2-oxo-4-(2-quinolin-3-ylacetyl)-1,4-diazepan-1-yl]-3-naphthalen-2-ylpropanamide	IC50	70.0 [1]
	(E)-3-[3-Chloro-4-(1H-indole-5-ylthio)phenyl]-1-(4-acetylpiperazine-1-yl)-2-propene-1-one	IC50	20.0 [1]
	(S)-2-(2-Bromo-benzoylamino)-succinamic acid	IC50	1080.0 [1]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[(4-hydroxy-3-methoxyphenyl)methyl]-4-[2-(methylamino)-2-oxoethyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	50.0 [1], 250.0 [2]
	3-[3-Nitro-4-(2,3-dichlorophenylthio)phenyl]-1-(4-acetylpiperazino)-2-propene-1-one	IC50	100.0 [1]
	(E)-3-[3-Chloro-4-(2,4-dichlorophenyl)sulfanylphenyl]-1-(4-methylpiperazin-1-yl)prop-2-en-1-one	IC50	1100.0 [1]
	3-[3-Chloro-4-(2,4-dichlorophenylthio)phenyl]-1-morpholino-2-propene-1-one	IC50	460.0 [1]
	3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl]-N-[3-(2-oxo-pyrrolidin-1-yl)-propyl]-acrylamide	IC50	550.0 [1]
	1-[2-[2,3-Dichloro-4-[2-[3-(2-oxopyrrolidin-1-yl)propylcarbamoyl]cyclopropyl]phenyl]sulfanylphenyl]piperidine-3-carboxylic acid	IC50	15.0 [1], 33.0 [2]
	4-[2-[4-[(E)-3-Morpholin-4-yl-3-oxoprop-1-enyl]-2,3-bis(trifluoromethyl)phenyl]sulfanylphenoxy]cyclohexane-1-carboxylic acid	IC50	1.8 [1], 4.0 [2]
	4-[[3-[4-[(E)-3-Morpholin-4-yl-3-oxoprop-1-enyl]-2,3-bis(trifluoromethyl)phenyl]sulfanylanilino]methyl]cyclohexane-1-carboxylic acid	IC50	1.4 [1], 3.2 [2]
	4-[3-[4-[(E)-3-Morpholin-4-yl-3-oxoprop-1-enyl]-2,3-bis(trifluoromethyl)phenyl]sulfanylphenoxy]cyclohexane-1-carboxylic acid	IC50	3.0 [1], 18.0 [2]
	4-[3-[4-[(E)-3-Morpholin-4-yl-3-oxoprop-1-enyl]-2,3-bis(trifluoromethyl)phenyl]sulfanylanilino]cyclohexane-1-carboxylic acid	IC50	0.5 [1], 2.4 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-propan-2-ylphenyl)propanoic acid	IC50	10.0 [1], 10000.0 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(5-methylsulfonylfuran-2-yl)propanoic acid	IC50	6.0 [1], 240.0 [2]
	1-[2-[2,3-Dichloro-4-(2-isopropylphenylthio)phenyl]cyclopropylcarbonyl]piperidine-2-carboxylic acid	IC50	33.0 [1], 1480.0 [2]
	4-[[2-[4-[(E)-3-Morpholin-4-yl-3-oxoprop-1-enyl]-2,3-bis(trifluoromethyl)phenyl]sulfanylphenoxy]methyl]cyclohexane-1-carboxylic acid	IC50	0.4 [1], 0.6 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid	IC50	3.0 [1], 200.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-ethylsulfonylphenyl)propanoic acid	IC50	2.0 [1], 180.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-(1,3-benzodioxol-5-ylmethyl)-4-(2-methoxy-2-oxoethyl)-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	1000.0 [1], 2590.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-4-[2-(methylamino)-2-oxoethyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	1150.0 [1], 5590.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-4-(2-methoxy-2-oxoethyl)-3-[[4-(methylcarbamoyl)phenyl]methyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	1300.0 [1], 30000.0 [2]
	[(1S,3R,7S,8S,8Ar)-3,7-dimethyl-8-[2-[(4R,6R)-4-[2-(methylamino)-2-oxoethyl]-3-[[4-(methylcarbamoyl)phenyl]methyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	620.0 [1], 30000.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[(3-methoxyphenyl)methyl]-4-[2-(methylamino)-2-oxoethyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	270.0 [1], 6500.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-4-(2-methoxy-2-oxoethyl)-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	30000.0 [1]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[(4-hydroxy-3-methoxyphenyl)methyl]-4-(2-methoxy-2-oxoethyl)-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	50.0 [1], 120.0 [2]
	4-[[(4R,6R)-6-[2-[(1S,2S,6R,8S,8Ar)-2,6-dimethyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]-4-[2-(methylamino)-2-oxoethyl]-2-oxo-1,3-oxazinan-3-yl]methyl]benzoic acid	IC50	870.0 [1], 30000.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[[4-(2-hydroxypropan-2-yl)phenyl]methyl]-4-(2-methoxy-2-oxoethyl)-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	3000.0 [1], 7690.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-4-(2-methoxy-2-oxoethyl)-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	640.0 [1], 20500.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-4-[2-(methylamino)-2-oxoethyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	800.0 [1], 9500.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-4-(2-methoxy-2-oxoethyl)-3-[(3-methoxyphenyl)methyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	680.0 [1], 4500.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-fluoro-5-methylsulfonylphenyl)propanoic acid	IC50	10.0 [1], 260.0 [2]
	4-[[3-[4-[(E)-3-Morpholin-4-yl-3-oxoprop-1-enyl]-2,3-bis(trifluoromethyl)phenyl]sulfanylphenoxy]methyl]cyclohexane-1-carboxylic acid	IC50	3.4 [1]
	(E)-3-[4-[2-(4-Methylcyclohexyl)oxyphenyl]sulfanyl-2,3-bis(trifluoromethyl)phenyl]-1-morpholin-4-ylprop-2-en-1-one	IC50	18.0 [1], 51.0 [2]
	(E)-3-[4-[3-(4-Methylcyclohexyl)oxyphenyl]sulfanyl-2,3-bis(trifluoromethyl)phenyl]-1-morpholin-4-ylprop-2-en-1-one	IC50	810.0 [1], 860.0 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(1-propan-2-yltriazol-4-yl)propanoic acid	IC50	59.0 [1], 1000.0 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(7-methyl-1-methylsulfonylindole-3-carbonyl)amino]propanoic acid	IC50	140.0 [1], 25000.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(1-propan-2-yltriazol-4-yl)propanoic acid	IC50	19.0 [1], 950.0 [2]
	(2S)-2-[[2-(1-Benzofuran-2-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(1-propan-2-yltriazol-4-yl)propanoic acid	IC50	5.0 [1], 190.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(2-methylsulfonyl-1H-imidazol-5-yl)propanoic acid	IC50	30.0 [1], 560.0 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(5-methyl-1-methylsulfonylindole-3-carbonyl)amino]propanoic acid	IC50	26.0 [1], 11000.0 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(6-methyl-1-methylsulfonylindole-3-carbonyl)amino]propanoic acid	IC50	39.0 [1], 25000.0 [2]
	(2S)-2-[[5,7-Dichloro-2-(pyrazolo[1,5-a]pyridine-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(1-propan-2-yltriazol-4-yl)propanoic acid	IC50	7.0 [1], 260.0 [2]
	(2S)-2-[[5,7-Dichloro-2-(4-chlorobenzoyl)-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[(1-methylsulfonylindole-3-carbonyl)amino]propanoic acid	IC50	100.0 [1], 25000.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(5-methylsulfonylpyridin-3-yl)propanoic acid	IC50	32.0 [1], 39.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-sulfamoylphenyl)propanoic acid	IC50	4.0 [1], 200.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(4-chloro-3-methylsulfonylphenyl)propanoic acid	IC50	120.0 [1], 2000.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-chloro-5-methylsulfonylphenyl)propanoic acid	IC50	10.0 [1], 200.0 [2]
	2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(5-methylsulfinylpyridin-3-yl)propanoic acid	IC50	50.0 [1], 57.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-propan-2-ylsulfonylphenyl)propanoic acid	IC50	200.0 [1], 10000.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[3-(methylsulfamoyl)phenyl]propanoic acid	IC50	13.0 [1], 640.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[3-(dimethylsulfamoyl)phenyl]propanoic acid	IC50	10.0 [1], 10000.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-dimethylphosphorylphenyl)propanoic acid	IC50	58.0 [1], 490.0 [2]
	(2S)-3-(3-Acetylphenyl)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]propanoic acid	IC50	12.0 [1], 5600.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[3-[(1R)-1-hydroxyethyl]phenyl]propanoic acid	IC50	10.0 [1], 4000.0 [2]
	(2S)-2-[[2-(1-Benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-[3-[(1S)-1-hydroxyethyl]phenyl]propanoic acid	IC50	14.0 [1], 940.0 [2]
	[(1S,3R,7S,8S,8Ar)-8-[2-[(4R,6R)-3-(1,3-benzodioxol-5-ylmethyl)-4-[2-(methylamino)-2-oxoethyl]-2-oxo-1,3-oxazinan-6-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate	IC50	170.0 [1], 6420.0 [2]
	Lovastatin	IC50	3780.0 [1]
	Benzotript	IC50	169000.0 [1]
	(R)-5-(4-Bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione	IC50	26.0 [1]
	(2S)-1-[(2S)-2-[[(2S)-3-Carboxy-2-[[(2S)-4-methyl-2-[[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]amino]pentanoyl]amino]propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carboxylic acid	IC50	100000.0 [1]
	Chlorphenethazine	IC50	28000.0 [1]
	5-[[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl]methyl]thiophene-3-carboxylic acid	IC50	20.0 [1]
	2-Bromohippuric acid	IC50	313500.0 [1]
	(2S)-2-[(2-Chlorobenzoyl)amino]-3-(1H-indol-3-yl)propanoic acid	IC50	1500.0 [1]
	3-Chloro-4-(1-chloro-naphthalen-2-ylsulfanyl)-phenylamine	IC50	2300.0 [1]
	N-Benzoyl-L-Tryptophan	IC50	127000.0 [1]
	1-[(E)-3-[4-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfanyl)-3-(trifluoromethyl)phenyl]prop-2-enoyl]piperidine-4-carboxylic acid	IC50	30.0 [1]
	Ethyl (2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(thiophene-2-carbonylamino)propanoate	IC50	950.0 [1]
	(2S)-2-[[(4S)-3-Acetyl-1,3-thiazolidine-4-carbonyl]amino]-3-[4-[(2,6-dichlorophenyl)methoxy]phenyl]propanoic acid	IC50	200000.0 [1]
	(E)-1-(4-Acetylpiperazin-1-yl)-3-[3-chloro-4-(1H-indol-6-ylsulfanyl)phenyl]prop-2-en-1-one	IC50	150.0 [1]
	(E)-1-(4-Acetylpiperazin-1-yl)-3-[3-chloro-4-[(5-ethoxy-2,3-dihydro-1,4-benzodioxin-6-yl)sulfanyl]phenyl]prop-2-en-1-one	IC50	100.0 [1]
	(2S)-2-[(3S,5R)-5-Methyl-3-(2-methylpropyl)-2-oxo-4-(2-quinolin-6-ylacetyl)-1,4-diazepan-1-yl]-3-naphthalen-2-ylpropanamide	IC50	110.0 [1]
	(E)-3-[4-[2-[[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]methyl]phenyl]sulfanyl-3-chlorophenyl]-1-morpholin-4-ylprop-2-en-1-one	IC50	100.0 [1]
	3-[3-Chloro-4-[2-(3-morpholino-3-oxo-1-propenyl)phenylthio]phenyl]-1-morpholino-2-propene-1-one	IC50	180.0 [1]
	1-[6-[4-(2-Propan-2-ylphenyl)sulfanyl-3-(trifluoromethyl)phenyl]pyrimidin-4-yl]piperidine-3-carboxylic acid	IC50	120.0 [1]
	1-[4-[4-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfanyl)-3-(trifluoromethyl)phenyl]pyridin-2-yl]piperidine-3-carboxylic acid	IC50	30.0 [1]
	1-[4-[4-(2,3-Dihydro-1,4-benzodioxin-6-ylsulfanyl)-3-(trifluoromethyl)phenyl]pyridin-2-yl]piperidine-4-carboxylic acid	IC50	50.0 [1]
	(2S)-2-[(3S)-4-[(4-Hydroxy-3-methoxyphenyl)methyl]-3-(2-methylpropyl)-2,5-dioxo-1,4-diazepan-1-yl]-N-methyl-3-naphthalen-2-ylpropanamide	IC50	950.0 [1]
	[1-[6-[4-(2-Propan-2-ylphenyl)sulfanyl-3-(trifluoromethyl)phenyl]pyrimidin-4-yl]piperidin-3-yl]methanol	IC50	230.0 [1]
	(2S)-2-[(3S)-4-[[4-(Dimethylamino)phenyl]methyl]-3-(2-methylpropyl)-2,5-dioxo-1,4-diazepan-1-yl]-N-methyl-3-naphthalen-2-ylpropanamide	IC50	800.0 [1]
	3-[3-Nitro-4-(2-ethylphenylthio)phenyl]-1-(4-acetylpiperazino)-2-propene-1-one	IC50	65.0 [1]
	3-[3-Chloro-4-[2-(morpholinomethyl)phenylthio]phenyl]-1-morpholino-2-propene-1-one	IC50	150.0 [1]
	3-[3-Chloro-4-[2-(4-formylpiperazinomethyl)phenylthio]phenyl]-1-morpholino-2-propene-1-one	IC50	420.0 [1]
	Ethyl 2-[[2-[2-chloro-4-[(E)-3-morpholin-4-yl-3-oxoprop-1-enyl]phenyl]sulfanylphenyl]methyl-methylamino]acetate	IC50	260.0 [1]
	2-[1-[6-[4-(2-Propan-2-ylphenyl)sulfanyl-3-(trifluoromethyl)phenyl]pyrimidin-4-yl]piperidin-4-yl]ethanol	IC50	230.0 [1]
	4-[4-(2-Propan-2-ylphenyl)sulfanyl-3-(trifluoromethyl)phenyl]-6-[4-(2H-tetrazol-5-yl)piperidin-1-yl]pyrimidine	IC50	108.0 [1]
	(2S)-2-[(3S)-4-[(4-Bromophenyl)methyl]-3-(2-methylpropyl)-2,5-dioxo-1,4-diazepan-1-yl]-N-methyl-3-naphthalen-2-ylpropanamide	IC50	2950.0 [1]
	4-[4-(2-Propan-2-ylphenyl)sulfanyl-3-(trifluoromethyl)phenyl]-6-[3-(2H-tetrazol-5-yl)piperidin-1-yl]pyrimidine	IC50	51.0 [1]
	3-[3-Nitro-4-(2-aminophenylthio)phenyl]-1-(4-acetylpiperazino)-2-propene-1-one	IC50	620.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/intercellular-adhesion-molecule-icam-1-integrin-alpha-l-beta-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/intercellular-adhesion-molecule-icam-1-integrin-alpha-l-beta-2-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan