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Interferon-induced, double-stranded RNA-activated protein kinase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
5-(1H-Indol-3-ylmethylidene)imidazolidine-2,4-dioneIC5010500.0 [1], 11000.0 [2]
N-[2-(1H-Indol-3-yl)ethyl]-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC509000.0 [1]
N-[2-(1H-Indol-3-yl)ethyl]-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineKi3400.0 [1]
StaurosporineIC50100.0 [1]
1,9-PyrazoloanthroneIC508000.0 [1]
K252aIC50100.0 [1]
DorsomorphinIC5016000.0 [1]
6-Bromoindirubin-3'-oximeIC50600.0 [1]
Indirubin-3'-monoximeIC50100.0 [1]
7-Oxo-7h-Benzimidazo[2,1-A]benz[de]isoquinoline-3-Carboxylic AcidIC50100.0 [1]
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamideIC50250.0 [1]
N3-(4-Fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamineIC505000.0 [1]
CID 53469448IC50696.0 [1]
(3Z)-3-(1H-Imidazol-5-ylmethylene)-5-methoxy-1H-indol-2(3H)-oneIC505000.0 [1]
3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenolIC504000.0 [1]
9H-Purine-2,6-diamine, N2-(2-aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-, cis-IC503000.0 [1]
IsogranulatimideIC50100.0 [1]
CID 53469059IC50905.0 [1]
2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurineIC5016000.0 [1]
4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamideIC502000.0 [1]
Cdk4 InhibitorIC506000.0 [1]
JNK Inhibitor VIC50100.0 [1]
N-(5-Methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amineIC5015000.0 [1]
(E)-3-(2,3,4,5-Tetrabromophenyl)acrylic acidIC507000.0 [1]
Cdk1/2 Inhibitor IIIIC501600.0 [1]
Tpl2 Kinase InhibitorIC50250.0 [1]
Aurora Kinase Inhibitor IIIIC5020000.0 [1]
1H-Pyrazolo[3,4-b]quinoxalin-3-amineIC506000.0 [1]
4-[(Z)-(5-Bromoindol-3-ylidene)methyl]-5-hydroxy-1,3-dihydroimidazol-2-oneIC504000.0 [1]
JNK Inhibitor II, Negative ControlIC5012000.0 [1]
Indirubin E804IC50100.0 [1]
Ripk1-IN-7IC50210.0 [1]
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3mIC508000.0 [1]
4-[[2-[4-Chloro-3-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]anilino]-1,3-benzoxazol-5-yl]oxy]-N-methylpyridine-2-carboxamideIC5040000.0 [1]
N-[5-(6,7-Dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1-methyl-3-oxo-2,5-diphenylpyrazole-4-carboxamideIC50480000.0 [1]
(5E)-6-Hydroxy-5-[(5-hydroxy-1H-indol-3-yl)methylidene]-3-methylpyrimidine-2,4(3H,5H)-dioneIC503000.0 [1]
5-(1H-Indazol-6-ylimino)-6-methylidene-1,2,4-triazinan-3-oneIC5016000.0 [1]
5-Bromo-2-hydroxy-N'-[(3E)-5-methoxy-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazideIC509400.0 [1]
N~6~-[4-(Trifluoromethoxy)phenyl]-7H-purine-2,6-diamineIC5020000.0 [1]
N-[4-(4-Methylpiperazin-1-yl)phenyl]-6-nitroquinazolin-4-amineIC5015000.0 [1]
N-[2-(1H-Indol-3-yl)ethyl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-amineIC5019000.0 [1]
4-(Aminomethyl)-N-[(5-bromo-2-hydroxy-1H-indol-3-yl)imino]benzamideIC5012000.0 [1]
(3Z)-3-({[3-(Methylthio)phenyl]amino}methylene)-1,3-dihydro-2H-indol-2-oneIC502500.0 [1]
N-[5-(6,7-Dimethoxyquinolin-4-yl)oxypyridin-2-yl]-4-(methylamino)-2-oxo-1-phenylpyridine-3-carboxamideIC501000.0 [1]
1-[5-(4-Aminothieno[3,2-C]pyridin-3-Yl)-2,3-Dihydro-1h-Indol-1-Yl]-2-PhenylethanoneIC5010000.0 [1]
1-[5-[4-Amino-7-(1-methylpyrazol-4-yl)thieno[3,2-c]pyridin-3-yl]-2,3-dihydroindol-1-yl]-2-phenylethanoneIC50978.0 [1]
1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-[6-(trifluoromethyl)pyridin-2-yl]ethanoneIC50359.0 [1]
1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(3,5-dimethylpyrazol-1-yl)ethanoneIC5099.0 [1]
5-{1-[(3-Chlorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amineIC50291.0 [1]
3-[1-(Phenylacetyl)-2,3-dihydro-1H-indol-5-yl]-7-(3-pyridinyl)thieno[3,2-c]pyridin-4-amineIC5010000.0 [1]
N-Cyclopentyl-4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-amineIC50100000.0 [1]
4-(5-Chloro-2-methyl-1H-indol-3-yl)-N-(3-methoxypropyl)pyrimidin-2-amineIC503000.0 [1]
4-(5-Methoxy-1H-indol-3-yl)-N-(2-morpholin-4-ylethyl)pyrimidin-2-amineIC50100000.0 [1]
4-(5-Chloro-2-methyl-1H-indol-3-yl)-N-(2-morpholin-4-ylethyl)pyrimidin-2-amineIC5012000.0 [1]
4-[4-(2-Methyl-1H-indol-3-yl)pyrimidin-2-yl]morpholineIC5090000.0 [1]
Methyl 3-[2-(2-hydroxyethylamino)pyrimidin-4-yl]-1H-indole-6-carboxylateIC509000.0 [1]
Methyl 3-[2-[2-(dimethylamino)ethylsulfanyl]pyrimidin-4-yl]-1H-indole-6-carboxylateIC50100000.0 [1]
N-(4-Chlorophenyl)-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC50600.0 [1]
N-(3,4-Difluorophenyl)-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC501500.0 [1]
N-Cyclopentyl-4-(5-methoxy-2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC501500.0 [1]
5-Chloro-3-[2-[4-(4-fluorophenyl)piperazin-1-yl]pyrimidin-4-yl]-2-methyl-1H-indoleIC50100000.0 [1]
4-(2-Methyl-1H-indol-3-yl)-N-pyridin-3-ylpyrimidin-2-amineIC50100.0 [1]
4-(5-Chloro-2-methyl-1H-indol-3-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amineIC5048000.0 [1]
3-[2-[4-(4-Fluorophenyl)piperazin-1-yl]pyrimidin-4-yl]-2-methyl-1H-indoleIC50100000.0 [1]
Methyl 3-[2-(2-morpholin-4-ylethylamino)pyrimidin-4-yl]-1H-indole-6-carboxylateIC5018000.0 [1]
2-[[4-(2-Methyl-1H-indol-3-yl)pyrimidin-2-yl]amino]ethanolIC5011000.0 [1]
N-(3-Chlorophenyl)-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC50300.0 [1]
4-(5-Chloro-2-methyl-1H-indol-3-yl)-N-cyclopentylpyrimidin-2-amineIC508000.0 [1]
4-(5-Chloro-2-methyl-1H-indol-3-yl)-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidin-2-amineIC50100.0 [1]
N-(3-Methoxypropyl)-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC501500.0 [1]
3-Methyl-2-[[4-(2-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino]butan-1-olIC5050000.0 [1]
4-(5-Methoxy-2-methyl-1H-indol-3-yl)-N-(4-methoxyphenyl)pyrimidin-2-amineIC5055000.0 [1]
6-[(2-Oxo-1,3-dihydroindol-6-yl)oxy]-1,3-dihydroindol-2-oneIC5014000.0 [1]
N-(2-Morpholin-4-ylethyl)-4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-amineIC5012000.0 [1]
N-(2-Chlorophenyl)-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC5019000.0 [1]
N-[2-(1H-Indol-3-yl)ethyl]-4-(5-pyridin-4-yl-1H-pyrazol-4-yl)pyrimidin-2-amineIC5051000.0 [1]
2-Methyl-3-[2-(4-pyridin-2-ylpiperazin-1-yl)pyrimidin-4-yl]-1H-indoleIC50100000.0 [1]
4-(2-Methyl-1H-indol-3-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amineIC5045000.0 [1]
3-(9-Nitro-6-oxo-7,7a,12,12a-tetrahydro-5H-indolo[3,2-d][1]benzazepin-2-yl)propanenitrileIC503500.0 [1]
4-(5-Chloro-2-methyl-1H-indol-3-yl)-N-(3-chlorophenyl)pyrimidin-2-amineIC502500.0 [1]
N-(4-Fluorophenyl)-4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-amineIC507000.0 [1]
4-(2-Phenyl-1H-indol-3-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amineIC50100000.0 [1]
28-Oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaen-3-oneIC50750.0 [1]
2-[[4-(1H-Indol-3-yl)pyrimidin-2-yl]amino]ethanolIC5011000.0 [1]
5-Chloro-2-methyl-3-(2-pyrrolidin-1-ylpyrimidin-4-yl)-1H-indoleIC50100000.0 [1]
N-(4-Fluorophenyl)-4-(2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC50150.0 [1]
N-(4-Chlorophenyl)-4-(5-methoxy-2-methyl-1H-indol-3-yl)pyrimidin-2-amineIC5050000.0 [1]
3-[2-[4-(4-Fluorophenyl)piperazin-1-yl]pyrimidin-4-yl]-1H-indoleIC50100000.0 [1]
2-Methyl-3-(2-pyrrolidin-1-ylpyrimidin-4-yl)-1H-indoleIC50100000.0 [1]
4-[(2Z)-2-(3-Methylidene-5-oxopyrazolidin-4-ylidene)hydrazinyl]benzenesulfonamideIC5011000.0 [1]
N-[2-(1H-Indol-3-yl)ethyl]-1-methyl-4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amineIC5011000.0 [1]
2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)phenyl]-4-Methyl-3-[2-(Methylamino)quinazolin-6-Yl]benzamideIC5010000.0 [1]
5-(1H-Indazol-6-ylamino)-2H-1,2,4-triazin-3-oneIC5013000.0 [1]
4-(7-Methoxy-5H-pyrimido[5,4-b]indol-4-yl)piperazine-1-carboxamideIC5013000.0 [1]
Items per page: 1 - 10 of 94
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References

This online tool may be cited as follows

MLA

"Quest Database™ Interferon-induced, double-stranded RNA-activated protein kinase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/interferon-induced-double-stranded-rna-activated-protein-kinase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Interferon-induced, double-stranded RNA-activated protein kinase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/interferon-induced-double-stranded-rna-activated-protein-kinase-inhibitors-ic50-ki.
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