 | Navarixin | IC50 | 0.05 [1], 1.0 [2], 2.6 [3], 450.0 [4], 680.0 [5] |
| Navarixin | Ki | 4.0 [1], 5.0 [2] |
 | CID 46897162 | IC50 | 60.0 [1] |
 | (R)-3-(3,4-Dioxo-2-(1-phenylpropylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide | IC50 | 6.8 [1], 48.0 [2] |
| (R)-3-(3,4-Dioxo-2-(1-phenylpropylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide | Ki | 4.0 [1], 4.4 [2], 4.7 [3] |
 | 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea | IC50 | 22.0 [1], 30.0 [2], 40.0 [3] |
 | [2-[[5-[(4-Fluorophenyl)carbamoyl]pyridin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid | IC50 | 21.0 [1], 22.0 [2], 130.0 [3] |
 | Elubrixin | IC50 | 5.1 [1], 260.7 [2], 310.5 [3] |
 | (2R)-2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1-propanol | IC50 | 3.98 [1], 4.0 [2] |
 | 2-(5-(2,3-Difluorobenzylthio)-2-aminothiazolo[4,5-d]pyrimidin-7-ylamino)-2-methylpropan-1-ol | IC50 | 14.0 [1], 15.85 [2], 25.12 [3] |
 | 1-(2-Chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-propan-2-ylsulfonylphenyl)urea | IC50 | 0.4 [1], 0.5 [2], 10.0 [3] |
 | 3-[[3,4-Dioxo-2-(pentan-3-ylamino)cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | IC50 | 5.0 [1], 15.0 [2], 19.1 [3] |
 | Reparixin | IC50 | 1.0 [1], 100.0 [2] |
 | Danirixin | IC50 | 5.0 [1], 30000.0 [2] |
 | N-[6,7-Dichloro-3-(5-thiophen-2-ylthiophen-2-yl)quinoxalin-2-yl]-N',N'-diethylbutane-1,4-diamine | IC50 | 110.0 [1] |
 | 2-Methyl-5-[(phenylsulfanyl)methyl]pyrazolo[1,5-a]pyrimidin-7-ol | IC50 | 2000.0 [1], 10300.0 [2] |
 | 1-(2-Hydroxy-4-nitrophenyl)-3-phenylurea | IC50 | 320.0 [1] |
 | [5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanyl]acetic acid | IC50 | 1200.0 [1], 5000.0 [2] |
 | 3-[[2-[[(1R)-1-(3-Fluorophenyl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | IC50 | 4.9 [1] |
| 3-[[2-[[(1R)-1-(3-Fluorophenyl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | Ki | 9.0 [1] |
 | 3-[[3,4-Dioxo-2-[[(1R)-1-thiophen-2-ylpropyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | IC50 | 6.0 [1] |
| 3-[[3,4-Dioxo-2-[[(1R)-1-thiophen-2-ylpropyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | Ki | 5.0 [1] |
 | 1-(4-Cyano-2-hydroxyphenyl)-3-phenylurea | IC50 | 200.0 [1] |
 | (2R)-2-[[2-Amino-5-[(phenylmethyl)thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1-propanol | IC50 | 13.0 [1] |
 | 5-Benzylsulfanyl-7-[[(2R)-1-hydroxypropan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one | IC50 | 4.5 [1], 5.0 [2] |
 | 5-[(2,3-Difluorophenyl)methylsulfanyl]-7-[[(2R)-1-hydroxypropan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one | IC50 | 1.0 [1] |
 | 2-Hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylthiophen-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide | IC50 | 5.3 [1] |
| 2-Hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylthiophen-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide | Ki | 5.0 [1] |
 | 3-(2-Hydroxyphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione | IC50 | 235.0 [1], 476.0 [2] |
 | 2-[[2-Amino-5-[[(2-fluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-(2R)-1-propanol | IC50 | 12.59 [1], 13.0 [2] |
 | CID 24879232 | IC50 | 5.0 [1], 50.0 [2] |
 | (R)-2-(5-(2,3-Difluorobenzylthio)-2-aminothiazolo[4,5-d]pyrimidin-7-ylamino)butan-1-ol | IC50 | 9.5 [1], 25.12 [2] |
 | (2R)-2-[[2-Amino-5-[(3-chloro-2-fluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol | IC50 | 3.0 [1], 3.98 [2] |
 | (2R)-2-[[2-Amino-5-(furan-2-ylmethylsulfanyl)-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol | IC50 | 31.62 [1], 35.0 [2] |
 | 4-(3,4-Dioxo-2-(phenylamino)cyclobut-1-enylamino)-3-hydroxybenzonitrile | IC50 | 3.0 [1], 15.0 [2] |
 | 3-(2-Hydroxy-4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione | IC50 | 22.0 [1], 36.0 [2] |
 | (R)-2-(2-Amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-ylamino)butan-1-ol | IC50 | 120.0 [1] |
| (R)-2-(2-Amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-ylamino)butan-1-ol | Ki | 160.0 [1] |
 | 1-(4-Chloro-2-hydroxy-3-sulfamoyl-phenyl)-3-(2,3-dichlorophenyl)urea | IC50 | 2.0 [1], 316.23 [2] |
 | 1-(2-Bromophenyl)-3-(4-cyano-2-hydroxyphenyl)urea | IC50 | 25.0 [1] |
 | (2R)-2-[[2-Amino-5-[(2-methyl-1,3-thiazol-4-yl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]propan-1-ol | IC50 | 120.0 [1], 125.89 [2] |
 | 1-[4-Chloro-2-hydroxy-3-[(3S)-3-methyloxolan-3-yl]sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 5.2 [1], 39.81 [2] |
 | 3-(2-(Cyclopentylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide | IC50 | 8.0 [1], 144.8 [2] |
 | 3-[(2-Chlorophenyl)amino]-7-nitro-4H-1,2,4-benzothiadiazin-5-ol 1,1-dioxide | IC50 | 81.0 [1], 1100.0 [2] |
 | 7-Nitro-3-{[2-(phenyloxy)phenyl]amino}-4H-1,2,4-benzothiadiazin-5-ol 1,1-dioxide | IC50 | 54.0 [1], 490.0 [2] |
 | 7-Chloro-3-(2-chloroanilino)-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-5-ol | IC50 | 92.0 [1], 520.0 [2] |
 | 1-(4-Chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)-3-(2,3-dichlorophenyl)urea | IC50 | 0.63 [1], 10000.0 [2] |
 | 3-[(2-Bromophenyl)amino]-7-nitro-4H-1,2,4-benzothiadiazin-5-ol 1,1-dioxide | IC50 | 26.0 [1], 600.0 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(3-pyrrolidin-1-ylcyclobutyl)sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.0 [1], 100.0 [2] |
 | 1-[4-Chloro-2-hydroxy-3-[(3R)-3-methyloxolan-3-yl]sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.0 [1], 158.49 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(3-methyloxolan-3-yl)sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.26 [1], 125.89 [2] |
 | 1-[4-Chloro-3-[3-(dimethylamino)cyclobutyl]sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.0 [1], 125.89 [2] |
 | 1-[4-Chloro-3-(1,1-difluoroethylsulfonyl)-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.4 [1], 630.96 [2] |
 | 1-(3-Tert-butylsulfonyl-4-cyano-2-hydroxyphenyl)-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.2 [1], 158.49 [2] |
 | 1-[4-Chloro-2-hydroxy-3-[2-(oxan-4-yl)propan-2-ylsulfonyl]phenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.5 [1], 398.11 [2] |
 | 1-[4-Chloro-3-[4-(fluoromethyl)oxan-4-yl]sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.26 [1], 251.19 [2] |
 | 1-[4-Chloro-3-[1-(2-fluoroethyl)piperidin-4-yl]sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.63 [1], 199.53 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(4-methyloxan-4-yl)sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.5 [1], 199.53 [2] |
 | 1-[4-Chloro-3-(4-fluorooxan-4-yl)sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.2 [1], 63.1 [2] |
 | Cxcr2-IN-1 | IC50 | 0.5 [1], 25.12 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(oxolan-3-ylsulfonyl)phenyl]-3-(2,3-dichlorophenyl)urea | IC50 | 0.5 [1], 7.94 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(1-methylpiperidin-4-yl)sulfonylphenyl]-3-(2,3-dichlorophenyl)urea | IC50 | 1.58 [1], 158.49 [2] |
 | 1-[4-Chloro-3-(1-ethylpiperidin-4-yl)sulfonyl-2-hydroxyphenyl]-3-(2-chloro-3-fluorophenyl)urea | IC50 | 1.26 [1], 158.49 [2] |
 | 1-[4-Chloro-2-hydroxy-3-[(3S)-1-methylpyrrolidin-3-yl]sulfonylphenyl]-3-(2,3-dichlorophenyl)urea | IC50 | 1.26 [1], 251.19 [2] |
 | 1-[4-Chloro-3-(4-ethylpiperazin-1-yl)sulfonyl-2-hydroxyphenyl]-3-(2-chloro-3-fluorophenyl)urea | IC50 | 1.0 [1], 1995.26 [2] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-[(3S)-1-methylpyrrolidin-3-yl]sulfonylphenyl]urea | IC50 | 0.5 [1], 79.43 [2] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-[(4S)-1-methylazepan-4-yl]sulfonylphenyl]urea | IC50 | 0.5 [1], 100.0 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(4-methylpiperazin-1-yl)sulfonylphenyl]-3-(2,3-dichlorophenyl)urea | IC50 | 0.79 [1], 1000.0 [2] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]urea | IC50 | 1.58 [1], 1995.26 [2] |
 | 1-[4-Chloro-3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-2-hydroxyphenyl]-3-(2-chloro-3-fluorophenyl)urea | IC50 | 3.98 [1], 3162.28 [2] |
 | 1-[4-Chloro-3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]sulfonyl-2-hydroxyphenyl]-3-(2,3-dichlorophenyl)urea | IC50 | 10.0 [1], 15848.93 [2] |
 | 1-(4-Chloro-3-ethylsulfonyl-2-hydroxyphenyl)-3-(2,3-dichlorophenyl)urea | IC50 | 0.5 [1], 6309.57 [2] |
 | 1-(4-Chloro-2-hydroxy-3-propan-2-ylsulfonylphenyl)-3-(2,3-dichlorophenyl)urea | IC50 | 0.63 [1], 158.49 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(oxan-4-ylsulfonyl)phenyl]-3-(2,3-dichlorophenyl)urea | IC50 | 0.79 [1], 6.31 [2] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(piperidine-1-carbonyl)phenyl]urea | IC50 | 0.5 [1], 6.31 [2] |
 | 1-(3-Tert-butylsulfonyl-4-chloro-2-hydroxyphenyl)-3-(2-chloro-3-fluorophenyl)urea | IC50 | 0.5 [1], 39.81 [2] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-[(2-methyl-2-azaspiro[3.3]heptan-6-yl)sulfonyl]phenyl]urea | IC50 | 0.4 [1], 630.96 [2] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-[(7-methyl-7-azaspiro[3.5]nonan-2-yl)sulfonyl]phenyl]urea | IC50 | 2.0 [1] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-[(3-methyl-3-azaspiro[5.5]undecan-9-yl)sulfonyl]phenyl]urea | IC50 | 0.4 [1], 25.12 [2] |
 | 1-(2-Chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(pyrrolidine-1-carbonyl)phenyl]urea | IC50 | 1.0 [1], 7.94 [2] |
 | 1-[4-Chloro-3-(1-fluoro-2-methylpropan-2-yl)sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.63 [1], 100.0 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(1-methoxypropan-2-ylsulfonyl)phenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.26 [1], 398.11 [2] |
 | 1-[4-Chloro-2-hydroxy-3-[2-[(3S)-oxolan-3-yl]propan-2-ylsulfonyl]phenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.58 [1], 316.23 [2] |
 | 1-[4-Chloro-3-(1-cyclobutylpiperidin-4-yl)sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.4 [1], 501.19 [2] |
 | 1-[4-Chloro-3-[2-(dimethylamino)-1,1-difluoroethyl]sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 2.0 [1], 630.96 [2] |
 | 1-[4-Chloro-3-(4-ethyloxan-4-yl)sulfonyl-2-hydroxyphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.32 [1], 398.11 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(oxan-3-ylsulfonyl)phenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.58 [1], 251.19 [2] |
 | 1-[4-Chloro-2-hydroxy-3-(3-methyloxan-3-yl)sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 2.0 [1], 199.53 [2] |
 | 1-(3-Tert-butylsulfonyl-4-chloro-2-hydroxyphenyl)-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 1.0 [1], 316.23 [2] |
 | 3-[[4-[[(1R)-2,2-Dimethyl-1-(5-methylfuran-2-yl)propyl]amino]-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | IC50 | 21.0 [1] |
| 3-[[4-[[(1R)-2,2-Dimethyl-1-(5-methylfuran-2-yl)propyl]amino]-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | Ki | 91.0 [1] |
 | 2-[(2,6-Dichlorobenzyl)sulfanyl]-4-hydroxy-6-phenyl-5-pyrimidinecarbonitrile | IC50 | 4300.0 [1], 30000.0 [2] |
 | Nvp cxcr2 20 | IC50 | 40.0 [1], 140.0 [2] |
 | 2-Hydroxy-N,N-dimethyl-3-[[4-[[(1R)-2-methyl-1-(5-methylfuran-2-yl)propyl]amino]-1,2,5-thiadiazol-3-yl]amino]benzamide | IC50 | 36.0 [1] |
| 2-Hydroxy-N,N-dimethyl-3-[[4-[[(1R)-2-methyl-1-(5-methylfuran-2-yl)propyl]amino]-1,2,5-thiadiazol-3-yl]amino]benzamide | Ki | 2400.0 [1] |
 | 4-Tert-butyl-2-(4-chloro-2-hydroxy-3-propan-2-ylsulfonylanilino)-1H-pyrimidin-6-one | IC50 | 6.31 [1], 580.0 [2] |
 | 1-[4-Cyano-2-hydroxy-3-(4,4,4-trifluoro-2-methylbutan-2-yl)sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 0.16 [1], 1000.0 [2] |
 | 2-Hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)ethyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide | IC50 | 2.4 [1], 5.4 [2] |
 | 2-Benzyl-5-(2,3-difluorophenylsulfanylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol | IC50 | 330.0 [1], 350.0 [2] |
 | 3-[[2-[[(1R)-1-(4-Bromofuran-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide | IC50 | 2.0 [1], 3.5 [2] |
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