Name: JAK1/TYK2 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

JAK1/TYK2 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	Baricitinib	IC50	15.0 ^[1], 28.7 ^[2], 29.0 ^[3]
	N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide	IC50	189.0 ^[1], 2511.0 ^[2], 6450.0 ^[3]
	Tofacitinib	IC50	35.0 ^[1]
	Ruxolitinib	IC50	194.0 ^[1]
	Filgotinib	IC50	436.0 ^[1], 1500.0 ^[2]
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References

This online resource may be cited as follows

MLA	"Quest Database™ JAK1/TYK2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 5 Dec. 2025, https://www.aatbio.com/data-sets/jak1-tyk2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 5). Quest Database™ JAK1/TYK2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/jak1-tyk2-inhibitors-ic50-ki.
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