Janus Kinase (JAK) Inhibitors (IC50, Ki)

Name: Janus Kinase (JAK) Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Ruxolitinib	IC50	100.0 ^[1]
	CID 53344620	IC50	27.0 ^[1]
	[2-[6-(2-Ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]-(5-piperidin-1-ylpyrazin-2-yl)methanone	IC50	70.3 ^[1]
	4-[3-(1h-Benzimidazol-2-Yl)-1h-Indazol-6-Yl]-3-Ethylphenol	IC50	10.5 ^[1]
	6-(2-Ethyl-4-Hydroxyphenyl)-1h-Indazole-3-Carboxamide	IC50	19.1 ^[1]
	6-(2-Ethyl-4-Hydroxyphenyl)-N-(6-Methylpyridin-3-Yl)-1h-Indazole-3-Carboxamide	IC50	277.8 ^[1]
	6-(2-Methoxy-4-hydroxyphenyl)-3-1H-benzoimidazol-2-yl-1H-indazole	IC50	57.8 ^[1]
	3-1H-Benzoimidazol-2-yl-6-(3-hydroxyphenyl)-1H-indazole	IC50	572.7 ^[1]
	[2-[6-(2-Ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]-(4-fluorophenyl)methanone	IC50	35.0 ^[1]
	4-[3-(5-Benzyl-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl]-5-ethyl-2-fluorophenol	IC50	30.4 ^[1]
	3-Ethyl-4-[3-(5-methyl-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl]phenol	IC50	18.6 ^[1]
	3-Ethyl-4-[3-(5-methylsulfonyl-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl]phenol	IC50	39.1 ^[1]
	[(3R)-3-(3-Hydroxyphenyl)sulfonylpyrrolidin-1-yl]-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methanone	IC50	343.0 ^[1]
	4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-3-propan-2-ylphenol	IC50	250.3 ^[1]
	4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-3-ethyl-2-fluorophenol	IC50	204.8 ^[1]
	3-Ethyl-4-[3-(1H-imidazol-2-yl)-1H-indazol-6-yl]phenol	IC50	10.4 ^[1]
	6-(2-Ethyl-4-hydroxyphenyl)-N,N-dimethyl-1H-indazole-3-carboxamide	IC50	10000.0 ^[1]
	6-(2-Ethyl-4-hydroxyphenyl)-N-methyl-1H-indazole-3-carboxamide	IC50	9.1 ^[1]
	1-[2-[6-(2-Ethyl-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]ethanone	IC50	4.5 ^[1]
	4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-3-propylphenol	IC50	75.4 ^[1]
	4-[3-(1H-Benzimidazol-2-yl)-1H-indazol-6-yl]-5-ethyl-2-fluorophenol	IC50	47.9 ^[1]
	(E)-2-[(3S)-3-[4-Amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile	IC50	5.0 ^[1]

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MLA	"Quest Database™ Janus Kinase (JAK) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 7 May. 2024, https://www.aatbio.com/data-sets/janus-kinase-jak-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 7). Quest Database™ Janus Kinase (JAK) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/janus-kinase-jak-inhibitors-ic50-ki.
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Janus Kinase (JAK) Inhibitors (IC50, Ki)

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