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L-lactate dehydrogenase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
3-[[3-(Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino]-5-(3,5-difluorophenoxy)benzoic acidIC5012600.0 [1], 14500.0 [2]
(2R)-5-(2-Chlorophenyl)sulfanyl-4-hydroxy-2-(4-morpholin-4-ylphenyl)-2-thiophen-3-yl-1,3-dihydropyridin-6-oneIC50877.0 [1], 1440.0 [2]
Ldh-IN-1IC50517.0 [1], 854.0 [2]
CID 56844254IC5057000.0 [1]
2-[5-(3,4-Difluorophenyl)-3-oxo-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC5057000.0 [1]
2-[3-Phenyl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5025200.0 [1], 33500.0 [2]
2-[3-(3-Phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC509880.0 [1]
2-[3-Phenyl-4-(4-sulfamoylanilino)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5022400.0 [1], 26800.0 [2]
2-[3-(3-Phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC504350.0 [1], 4800.0 [2]
2-[3-Phenyl-5-pyridin-4-yl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5057000.0 [1]
2-[5-[3-(2-Fluorophenyl)phenyl]-3-oxo-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC5029900.0 [1], 30000.0 [2]
2-[5-Cyclopropyl-3-(3-phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC50983.0 [1], 1340.0 [2]
2-[5-Amino-3-(3-phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC509450.0 [1], 17700.0 [2]
2-[3-(3,4-Difluorophenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5030800.0 [1], 57000.0 [2]
2-[3-Oxo-5-(3-phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC5026800.0 [1], 27700.0 [2]
2-[5-Cyclopropyl-3-phenyl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5014700.0 [1], 17500.0 [2]
2-[3-(3-Phenylphenyl)-4-(4-sulfamoylanilino)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC507240.0 [1], 19900.0 [2]
2-[5-(3-Bromophenyl)-3-oxo-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acidIC5057000.0 [1]
2-[3-Phenyl-5-pyridin-3-yl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC5016500.0 [1], 26600.0 [2]
2-[5-(Cyclopropylmethyl)-3-phenyl-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC503370.0 [1], 5120.0 [2]
2-[5-Cyclopropyl-3-(3-phenylphenyl)-4-(4-sulfamoylphenoxy)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC501920.0 [1], 1960.0 [2]
Oxamic acidIC5025000000.0 [1]
2-[5-(Cyclopropylmethyl)-3-[3-(4,4-difluorocyclohexen-1-yl)-4-fluorophenyl]-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC501000.0 [1]
2-[5-(Cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-[3-[(E)-2-(5-methylthiophen-2-yl)ethenyl]phenyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC501000.0 [1]
2-[5-(Cyclopropylmethyl)-3-[4-fluoro-3-(6-methylcyclohexen-1-yl)phenyl]-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC501000.0 [1]
2-[5-(Cyclopropylmethyl)-3-[4-fluoro-3-(3-fluoro-4-methylphenyl)phenyl]-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC501000.0 [1]
2-[3-(3-Acetyl-4-fluorophenyl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC501000.0 [1]
2-[5-(Cyclopropylmethyl)-3-[4-fluoro-3-(4-methylcyclohexen-1-yl)phenyl]-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acidIC501000.0 [1]
Items per page: 1 - 10 of 28
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References

This online tool may be cited as follows

MLA

"Quest Database™ L-lactate dehydrogenase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/l-lactate-dehydrogenase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ L-lactate dehydrogenase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/l-lactate-dehydrogenase-inhibitors-ic50-ki.
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